5-hydroxytryptophan

1. 5-Hydroxy-L-tryptophan decarboxy-lyase

Catalysed by DDCcytosol

1. 5-Hydroxy-L-tryptophan decarboxy-lyase
2. acetyl-CoA:aralkylamine N-acetyltransferase

Catalysed by DDC, AANATcytosol

1. 5-Hydroxy-L-tryptophan decarboxy-lyase
2. transport of serotonin (cytosol to extracellular)

Catalysed by DDC, SLCO1A2, SLCO1B3cytosol, extracellular spaceOne of 2 routes

1. 5-Hydroxy-L-tryptophan decarboxy-lyase
2. transport of GSH and serotonin (cytosol to extracellular)

Catalysed by DDC, SLCO1A2, SLCO1B3cytosol, extracellular spaceOne of 2 routes

1. 5-Hydroxy-L-tryptophan decarboxy-lyase
2. acetyl-CoA:aralkylamine N-acetyltransferase

Catalysed by DDC, AANATcytosol

1. 5-Hydroxy-L-tryptophan decarboxy-lyase
2. 5-hydroxy-L-tryptophan + H(+) = serotonin + CO2

Catalysed by DDCcytosol

1. 5-Hydroxy-L-tryptophan decarboxy-lyase
2. serotonin + 3'-phosphoadenylyl sulfate = serotonin O-sulfate + adenosine 3',5'-bisphosphate + H(+)

Catalysed by DDC, SULT1A3, SULT1A4cytosol

1. 5-Hydroxy-L-tryptophan decarboxy-lyase
2. transport of serotonin (cytosol to extracellular)

Catalysed by DDC, SLC6A4cytosol, extracellular space

1. 5-Hydroxy-L-tryptophan decarboxy-lyase
2. serotonin(out) + K(+)(in) + Na(+)(out) + H(+)(in) = serotonin(in) + K(+)(out) + Na(+)(in) + H(+)(out)

Catalysed by DDC, SLC6A4cytosol, inner side of the membrane, outer side of the membrane

1. 5-Hydroxy-L-tryptophan decarboxy-lyase
2. S-Adenosyl-L-methionine:amine N-methyltransferase

Catalysed by DDC, INMTcytosol

1. 5-Hydroxy-L-tryptophan decarboxy-lyase
2. 5-Hydroxytryptamine:oxygen oxidoreductase(deaminating)(flavin-containing)

Catalysed by DDC, MAOA, MAOBcytosolOne of 2 routes

1. 5-Hydroxy-L-tryptophan decarboxy-lyase
2. acetyl-CoA:aralkylamine N-acetyltransferase
3. Carnitine O-Palmitoyltransferase

Catalysed by DDC, AANAT, CPT1A, CPT1C and 1 morecytosolOne of 244 routes

1. 5-Hydroxy-L-tryptophan decarboxy-lyase
2. transport of serotonin (cytosol to extracellular)
3. transport of S-glutathionyl-2-4-dinitrobenzene (cytosol to extracellular)