a quinol

1. a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out)

Catalysed by CYC1, UQCRFS1outer side of the membraneOne of 6 routes

1. (S)-dihydroorotate + a quinone = orotate + a quinol

Catalysed by DHODH

1. 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone + H(+) = beta-nicotinamide D-riboside + a quinol

Catalysed by NQO2

1. trans-4-hydroxy-L-proline + a quinone = (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + a quinol + H(+)

Catalysed by PRODH2

1. L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+)

Catalysed by PRODH, PRODH2

1. a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out)
2. 2 a quinone + NADPH + H(+) = 2 a 1,4-benzosemiquinone + NADP(+)

Catalysed by CYC1, UQCRFS1, CRYZ, TP53I3 and 2 moreouter side of the membrane

1. (S)-dihydroorotate + a quinone = orotate + a quinol
2. (S)-dihydroorotate amidohydrolase

Catalysed by DHODH, CADcytosol

1. L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+)
2. L-proline(out) + L-alanine(in) + Na(+)(out) = L-proline(in) + L-alanine(out) + Na(+)(in)
3. amino-acid N-acetyltransferase (N-acetyl-L-alanine)

Catalysed by PRODH, PRODH2, SLC1A4inner side of the membrane, outer side of the membrane, mitochondrial matrix

1. L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+)
2. L-proline(out) + L-alanine(in) + Na(+)(out) = L-proline(in) + L-alanine(out) + Na(+)(in)
3. N(omega)-methyl-L-arginine + pyruvate = 5-(3-methylguanidino)-2-oxopentanoate + L-alanine