Compound

phosphocholine

Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.

Definition from MeSH (D010767), National Library of Medicine, read 2026-09-23. NLM revises MeSH; this copy may not reflect its current record.

CHEBI:295975ChEBI

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Structure

2D depiction · 3D model shown

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A generated conformer of phosphocholine — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, anion
Formula: C5H13NO4P
Mass: 182.136 g/mol
Charge: -1
InChIKey: YHHSONZFOIEMCP-UHFFFAOYSA-M
SMILES: C[N+](C)(C)CCOP(=O)([O-])[O-]
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

5 entities

5 entities reached.

0 reported hops5 assembled from the scaffold

PCYT1AProteinUNIPROT:P49585substrate ofInferred only13 paths13 endpoints
cholineCompoundCHEBI:15354converted toInferred only9 paths6 endpoints
PCYT1BProteinUNIPROT:Q9Y5K3substrate ofInferred only9 paths9 endpoints
PHOSPHO1ProteinUNIPROT:Q8TCT1substrate ofInferred only6 paths6 endpoints
ADPRMProteinUNIPROT:Q3LIE5substrate ofInferred only5 paths5 endpoints

What the reference databases state

Statements

12 statements

12 statements · 1 reference database · Subject: phosphocholine · Sources: Rhea

Order

phosphocholine is converted to CDP-cholineCompoundRhea RHEA:18997Inferred only
phosphocholine is converted to CDP-cholineCompoundRhea RHEA:32487Inferred only
CDP-choline is converted to phosphocholineCompoundRhea RHEA:32487Inferred only
choline is converted to phosphocholineCompoundRhea RHEA:10492Inferred only
choline is converted to phosphocholineCompoundRhea RHEA:12837Inferred only
phosphocholine is converted to cholineCompoundRhea RHEA:10492Inferred only
phosphoethanolamine is converted to phosphocholineCompoundRhea RHEA:32291Inferred only
phosphocholine is converted to phosphoethanolamineCompoundRhea RHEA:32291Inferred only
phosphocholine is a substrate of ADPRMProteinRhea RHEA:32487Inferred only
phosphocholine is a substrate of PCYT1AProteinRhea RHEA:18997Inferred only
phosphocholine is a substrate of PCYT1BProteinRhea RHEA:18997Inferred only
phosphocholine is a substrate of PHOSPHO1ProteinRhea RHEA:10492Inferred only

Reactions

35 reactions

phosphocholine+watercholine+hydrogenphosphate
Catalysed by PHOSPHO1
Reaction pageDirection not assertedBalanced
Rhea RHEA:10492CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phosphocholine+waterphosphocholine+a 1,2-diacyl-sn-glycerol+hydron
Catalysed by SMPD1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:10604CC BY 4.0Reference data
choline+ATP(4-)phosphocholine+ADP(3-)+hydron
Catalysed by CHKA or CHKB
Reaction pageLeft to rightBalanced
Rhea RHEA:12837CC BY 4.0Reference data
phosphocholine+CTP+hydronCDP-choline+diphosphate(3-)
Catalysed by PCYT1A or PCYT1B
Reaction pageLeft to rightBalanced
Rhea RHEA:18997CC BY 4.0Reference data
a sphingomyelin+waterphosphocholine+an N-acylsphing-4-enine+hydron
Catalysed by SMPD2 or SMPD1 or ENPP7 or SMPD4 or SMPD3
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:19253CC BY 4.0Reference data
sn-glycerol 3-phosphocholine+waterphosphocholine+glycerol+hydron
Catalysed by ENPP6
Reaction pageLeft to rightBalanced
Rhea RHEA:19545CC BY 4.0Reference data
CHEBI:58641+S-adenosyl-L-methioninephosphocholine+S-adenosyl-L-homocysteine+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:25325CC BY 4.0Reference data
phosphoethanolamine+3S-adenosyl-L-methioninephosphocholine+3S-adenosyl-L-homocysteine+3hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:32291CC BY 4.0Reference data
CDP-choline+waterphosphocholine+CMP+2hydron
Catalysed by ADPRM
Reaction pageDirection not assertedBalanced
Rhea RHEA:32487CC BY 4.0Reference data
CHEBI:70775+waterCHEBI:70846+phosphocholine+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:34739CC BY 4.0Reference data
a 1-O-alkyl-sn-glycero-3-phosphocholine+watera 1-O-alkyl-sn-glycerol+phosphocholine+hydron
Catalysed by ENPP6
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:36083CC BY 4.0Reference data
1-O-hexadecyl-sn-glycero-3-phosphocholine+water1-O-hexadecyl-sn-glycerol+phosphocholine+hydron
Catalysed by SMPD2
Reaction pageLeft to rightBalanced
Rhea RHEA:36087CC BY 4.0Reference data

Show the remaining 23

Other names

3 names

Resolves to: phosphocholine

Also called: 2-(trimethylammonio)ethyl phosphatecholine phosphate
Systematic name: 2-(trimethylazaniumyl)ethyl phosphate