Structure
Loading the model…
- Class
- Inorganic compound, anion
- Formula
- HS
- Mass
- 33.075 g/mol
- Charge
- -1
- InChIKey
- RWSOTUBLDIXVET-UHFFFAOYSA-M
- SMILES
- [H][S-]
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
9 entities
9 entities reached.
0 reported hops9 assembled from the scaffold
- SOD1ProteinUNIPROT:P00441substrate ofInferred only40 paths40 endpoints
- CBSProteinUNIPROT:P35520substrate ofInferred only32 paths32 endpoints
- SQORProteinUNIPROT:Q9Y6N5substrate ofInferred only28 paths7 endpoints
- SELENBP1ProteinUNIPROT:Q13228substrate ofInferred only10 paths10 endpoints
- SUMF1ProteinUNIPROT:Q8NBK3substrate ofInferred only9 paths9 endpoints
- MPSTProteinUNIPROT:P25325substrate ofInferred only8 paths8 endpoints
- L-cysteineCompoundCHEBI:17561converted toInferred only6 paths6 endpoints
- TSTD1ProteinUNIPROT:Q8NFU3substrate ofInferred only5 paths5 endpoints
- LIASProteinUNIPROT:O43766substrate ofInferred only4 paths4 endpoints
What the reference databases state
Statements
17 statements
17 statements · 2 reference databases · Subject: hydrogen sulfide · Sources: Human-GEM, Rhea
- hydrogen sulfide is converted to L-cysteineCompoundHuman-GEM MAR04323Inferred only
- hydrogen sulfide is converted to sulfateCompoundRhea RHEA:85007Inferred only
- sulfite is converted to hydrogen sulfideCompoundRhea RHEA:55316Inferred only
- hydrogen sulfide is converted to sulfiteCompoundRhea RHEA:55316Inferred only
- sulfite is converted to hydrogen sulfideCompoundRhea RHEA:13801Inferred only
- hydrogen sulfide is converted to sulfiteCompoundRhea RHEA:13801Inferred only
- hydrogen sulfide is a substrate of CBSProteinHuman-GEM MAR04323Inferred only
- hydrogen sulfide is a substrate of LIASProteinRhea RHEA:16585Inferred only
- hydrogen sulfide is a substrate of MPSTProteinRhea RHEA:21740Inferred only
- hydrogen sulfide is a substrate of SELENBP1ProteinRhea RHEA:11812Inferred only
- hydrogen sulfide is a substrate of SOD1ProteinRhea RHEA:85007Inferred only
- hydrogen sulfide is a substrate of SQORProteinRhea RHEA:38359Inferred only
Show the remaining 5
- hydrogen sulfide is a substrate of SQORProteinHuman-GEM MAR20186Inferred only
- hydrogen sulfide is a substrate of SQORProteinRhea RHEA:55156Inferred only
- hydrogen sulfide is a substrate of SQORProteinRhea RHEA:62608Inferred only
- hydrogen sulfide is a substrate of SUMF1ProteinRhea RHEA:51152Inferred only
- hydrogen sulfide is a substrate of TSTD1ProteinRhea RHEA:14505Inferred only
Reactions
67 reactions
L-cysteine+water2proton+hydrogen sulfide+ammonium+pyruvate
Catalysed by CTH
Reaction pageLeft to rightBalancedEC 4.4.1.1, 4.4.1.13cytosol
Human-GEM MAR04302CC BY 4.0Reference data
proton+hydrogen sulfide+L-seryl residueL-cysteine+water
Catalysed by CBS
Reaction pageLeft to rightBalancedEC 4.2.1.22cytosol
Human-GEM MAR04323CC BY 4.0Reference data
water+thiosulfate2proton+hydrogen sulfide+sulfate
Reaction pageLeft to rightBalancedEC 1.1.1.50cytosol
Human-GEM MAR04840CC BY 4.0Reference data
hydrogen sulfidehydrogen sulfide
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR04990CC BY 4.0Reference data
MAM00210m+3proton+NADPH(4-)+2S-adenosyl-L-methionine+tetra-mu3-sulfido-tetrairon(2+)MAM00208m+2MAM01098m+4iron(2+)+2hydrogen sulfide+2L-methionine+NADP(3-)
Catalysed by LIAS & FDX1 & FDXR & GCSH & ISCA1 or LIAS & FDX1 & FDXR & GCSH & ISCA2 or LIAS & FDX1 & FDXR & GCSH & NFU1
Reaction pageLeft to rightBalancedEC 2.8.1.8mitochondrial matrix
Human-GEM MAR06403CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR09103CC BY 4.0Reference data
FAD+CHEBI:16856+proton+hydrogen sulfideFADH2+S-sulfanylglutathione
Catalysed by SQOR
Reaction pageLeft to rightBalancedEC 1.8.5.8mitochondrial matrix
Human-GEM MAR20186CC BY 4.0Reference data
CHEBI:57524+hydrogen sulfide+hydronL-cysteine+hydrogenphosphate
Reaction pageDirection not assertedBalanced
Rhea RHEA:10252CC BY 4.0Reference data
[cypemycin](1-18)-L-Cys-L-Leu-L-Val-L-Cys+AC(3,19),S(21)-[cypemycin](1-18)-L-Ala-L-Leu-N-thioethenyl-L-valinamide+hydrogen sulfide+AH2+carbon dioxide
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:10904CC BY 4.0Reference data
D-cysteine+waterhydrogen sulfide+pyruvate+ammonium+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:11268CC BY 4.0Reference data
methanethiol+dioxygen+waterhydrogen sulfide+formaldehyde+hydrogen peroxide+hydron
Catalysed by SELENBP1
Reaction pageDirection not assertedBalanced
Rhea RHEA:11812CC BY 4.0Reference data
hydrogen sulfide+3NADP(3-)+3watersulfite+3NADPH(4-)+4hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:13801CC BY 4.0Reference data
Other names
7 names
Resolves to: hydrogen sulfide
- Also called
- HS anionHS(-)HS−hydrosulfide
- Systematic name
- hydrogen(sulfide)(1-)hydrogen(sulfide)(1−)sulfanide