Compound
(indol-3-yl)acetate
An indol-3-yl carboxylic acid anion that is the conjugate base of indole-3-acetic acid.
Definition from ChEBI (CHEBI:30854), read 2026-09-23. CC BY 4.0.
Structure
No depiction stored
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- Class
- Organic compound, anion
- Formula
- C10H8NO2
- Mass
- 174.179 g/mol
- Charge
- -1
- InChIKey
- SEOVTRFCIGRIMH-UHFFFAOYSA-M
- SMILES
- O=C([O-])Cc1cnc2ccccc12
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
3 entities
3 entities reached.
What the reference databases state
Statements
18 statements
18 statements · 2 reference databases · Subject: (indol-3-yl)acetate · Sources: Human-GEM, Rhea
- (indol-3-yl)acetate is converted to indole-3-acetaldehydeCompoundRhea RHEA:30867Inferred only
- (indol-3-yl)acetate is converted to indole-3-acetaldehydeCompoundRhea RHEA:16277Inferred only
- indole-3-acetaldehyde is converted to (indol-3-yl)acetateCompoundHuman-GEM MAR06714Inferred only
- indole-3-acetaldehyde is converted to (indol-3-yl)acetateCompoundHuman-GEM MAR08563Inferred only
- indole-3-acetaldehyde is converted to (indol-3-yl)acetateCompoundRhea RHEA:16277Inferred only
- indole-3-acetaldehyde is converted to (indol-3-yl)acetateCompoundRhea RHEA:30867Inferred only
- indole-3-acetamide is converted to (indol-3-yl)acetateCompoundHuman-GEM MAR09534Inferred only
- (indol-3-yl)acetate is converted to indole-3-acetamideCompoundRhea RHEA:34371Inferred only
- indole-3-acetamide is converted to (indol-3-yl)acetateCompoundRhea RHEA:34371Inferred only
- (indol-3-yl)acetate is converted to indole-3-pyruvateCompoundRhea RHEA:34331Inferred only
- indole-3-pyruvate is converted to (indol-3-yl)acetateCompoundRhea RHEA:34331Inferred only
- (indol-3-yl)acetate is converted to methyl (indol-3-yl)acetateCompoundHuman-GEM MAR06715Inferred only
Show the remaining 6
- (indol-3-yl)acetate is converted to methyl (indol-3-yl)acetateCompoundRhea RHEA:36131Inferred only
- methyl (indol-3-yl)acetate is converted to (indol-3-yl)acetateCompoundRhea RHEA:36131Inferred only
- (indol-3-yl)acetate is metabolised by COMTProteinHuman-GEM MAR06715Inferred only
- (indol-3-yl)acetate is a substrate of LRTOMTProteinHuman-GEM MAR06715Inferred only
- (indol-3-yl)acetate is transported by SLC22A6ProteinRhea RHEA:75983Inferred only
- (indol-3-yl)acetate is transported by SLC22A8ProteinRhea RHEA:75983Inferred only
Reactions
25 reactions
water+indole-3-acetaldehyde+NAD(+)2proton+(indol-3-yl)acetate+NADH(2-)
Catalysed by ALDH3A2 or ALDH2 or ALDH1B1 or ALDH9A1 or ALDH7A1
Reaction pageLeft to rightBalancedEC 1.2.1.3cytosol
Human-GEM MAR06714CC BY 4.0Reference data
(indol-3-yl)acetate+S-adenosyl-L-methioninemethyl (indol-3-yl)acetate+CHEBI:16680
Reaction pageLeft to rightBalancedEC 2.1.1.6cytosol
Human-GEM MAR06715CC BY 4.0Reference data
water+indole-3-acetaldehyde+NAD(+)2proton+(indol-3-yl)acetate+NADH(2-)
Catalysed by ALDH2 or ALDH1B1 or ALDH7A1
Reaction pageLeft to rightBalancedEC 1.2.1.4, 1.2.1.5mitochondrial matrix
Human-GEM MAR08563CC BY 4.0Reference data
indole-3-acetamide+waterproton+(indol-3-yl)acetate+ammonium
Catalysed by FAAH2
Reaction pageLeft to rightBalancedEC 3.5.1.4cytosol
Human-GEM MAR09534CC BY 4.0Reference data
(indol-3-yl)acetate(indol-3-yl)acetate
Reaction pageReversibleBalancedmitochondrial matrix, cytosol
Human-GEM MAR09676CC BY 4.0Reference data
(indol-3-yl)acetate(indol-3-yl)acetate
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR10378CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR11419CC BY 4.0Reference data
(indol-3-yl)acetate+L-lysine+ATP(4-)CHEBI:58105+ADP(3-)+hydrogenphosphate+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:14857CC BY 4.0Reference data
(indol-3-yl)acetate+UDP-alpha-D-glucoseCHEBI:17990+UDP
Reaction pageDirection not assertedBalanced
Rhea RHEA:14921CC BY 4.0Reference data
indole-3-acetaldehyde+dioxygen+water(indol-3-yl)acetate+hydrogen peroxide+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:16277CC BY 4.0Reference data
indole-3-acetaldehyde+NAD(1-)+water(indol-3-yl)acetate+NADH(2-)+2hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:30867CC BY 4.0Reference data
methyl (indol-3-yl)acetate+water(indol-3-yl)acetate+methanol+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:32919CC BY 4.0Reference data
Where it reaches
1 system, 1 region, 1 tissue, 1 transporter route — routes, not measurements: transporters known to carry (indol-3-yl)acetate are expressed there, and no source reports it arriving.
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Other names
2 names
Resolves to: (indol-3-yl)acetate
- Also called
- 2-(indol-3-yl)ethanoate
- Systematic name
- 1H-indol-3-ylacetate