What it touches on the way
Mechanistic reach
2 entities
2 entities reached.
0 reported hops2 assembled from the scaffold
What the reference databases state
Statements
3 statements
3 statements · 1 reference database · Subject: CHEBI:30249 · Sources: Human-GEM
- L-tryptophan is converted to CHEBI:30249CompoundHuman-GEM MAR04214Inferred only
- CHEBI:30249 is a substrate of AFMIDProteinHuman-GEM MAR04216Inferred only
- CHEBI:30249 is a substrate of KYNUProteinHuman-GEM MAR04218Inferred only
Reactions
3 reactions
dioxygen+L-tryptophanCHEBI:30249
Catalysed by IDO1 or TDO2 or IDO2
Reaction pageLeft to rightBalancedEC 1.13.11.11, 1.13.11.52cytosol
Human-GEM MAR04214CC BY 4.0Reference data
water+CHEBI:30249formic acid+proton+L-kynurenine
Catalysed by AFMID
Reaction pageLeft to rightBalancedEC 3.5.1.49, 3.5.1.9cytosol
Human-GEM MAR04216CC BY 4.0Reference data
water+CHEBI:30249L-alanine+N-formylanthranilic acid+proton
Catalysed by KYNU
Reaction pageLeft to rightBalancedEC 3.7.1.3cytosol
Human-GEM MAR04218CC BY 4.0Reference data
Other names
6 names
Resolves to: CHEBI:30249
- Also called
- 3-(2-formamidobenzoyl)-L-alanineL-FormylkynurenineN-Formyl-L-kynurenineN-FormylkynurenineN'-formylkynurenine
- Systematic name
- (2S)-2-amino-4-(2-formamidophenyl)-4-oxobutanoic acid