Compound
4-methylthio-2-oxobutanoic acid
A 2-oxo monocarboxylic acid derived from L-methionine via the action of methionine transaminase.
Definition from ChEBI (CHEBI:33574), read 2026-09-23. CC BY 4.0.
What it touches on the way
Mechanistic reach
1 entity
1 entities reached.
0 reported hops1 assembled from the scaffold
What the reference databases state
Chemical structure
- 4-methylthio-2-oxobutanoic acid has the functional parent butyric acidCompoundChEBI CHEBI:33574Inferred only
Statements
3 statements
3 statements · 1 reference database · Subject: 4-methylthio-2-oxobutanoic acid · Sources: Human-GEM
- 4-methylthio-2-oxobutanoic acid is converted to L-methionineCompoundHuman-GEM MAR05391Inferred only
- L-methionine is converted to 4-methylthio-2-oxobutanoic acidCompoundHuman-GEM MAR05390Inferred only
- 4-methylthio-2-oxobutanoic acid is a substrate of TATProteinHuman-GEM MAR05391Inferred only
Reactions
5 reactions
5-methylsulfanyl-2,3-dioxopentyl phosphate+water+dioxygen4-methylthio-2-oxobutanoic acid+formic acid+2proton+phosphate(3-)
Reaction pageLeft to rightBalancedGO:0005829
Human-GEM MAR00251CC BY 4.0Reference data
1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one+dioxygen4-methylthio-2-oxobutanoic acid+formic acid+2proton
Catalysed by ADI1
Reaction pageLeft to rightBalancedEC 1.13.11.54GO:0005829
Human-GEM MAR05389CC BY 4.0Reference data
water+L-methionine+dioxygen4-methylthio-2-oxobutanoic acid+proton+hydrogen peroxide+ammonium
Catalysed by IL4I1
Reaction pageLeft to rightBalancedEC 1.4.3.2GO:0005829
Human-GEM MAR05390CC BY 4.0Reference data
4-methylthio-2-oxobutanoic acid+L-glutamate(1-)2-oxoglutarate(2-)+L-methionine
Catalysed by TAT
Reaction pageLeft to rightBalancedEC 2.6.1.5GO:0005829
Human-GEM MAR05391CC BY 4.0Reference data
4-methylthio-2-oxobutanoic acid+L-glutamine+2protonL-glutamate(1-)+L-methionine
Reaction pageLeft to rightUnbalancedGO:0005829
Human-GEM MAR08607CC BY 4.0Reference data
Other names
7 names
Resolves to: 4-methylthio-2-oxobutanoic acid
- Also called
- 2-keto-4-methylthiobutyric acid2-Oxo-4-methylthiobutanoate2-oxomethionine4-(METHYLSULFANYL)-2-OXOBUTANOIC ACID4-Methylthio-2-oxobutanoatealpha-oxo-gamma-methylthiobutyric acidα-oxo-γ-methylthiobutyric acid