Compound

a carboxylate

The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated.

Definition from ChEBI (CHEBI:29067), read 2026-09-23. CC BY 4.0.

CHEBI:29067ChEBI

Open in the graph

Structure

2D depiction

Class: Inorganic compound, anion
Formula: CO2R
Mass: 44.01 g/mol
Charge: -1
SMILES: [1*]C(=O)[O-]
Look it up: ChEBI

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

11 entities

11 entities reached.

0 reported hops11 assembled from the scaffold

What the reference databases state

Statements

27 statements

27 statements · 1 reference database · Subject: a carboxylate · Sources: Rhea

Order

an acyl phosphate is converted to a carboxylateCompoundRhea RHEA:14965Inferred only
a carboxylate is converted to an acyl-CoACompoundRhea RHEA:10968Inferred only
a carboxylate is converted to an acyl-CoACompoundRhea RHEA:24336Inferred only
a carboxylate is converted to an acyl-CoACompoundRhea RHEA:70423Inferred only
an acyl-CoA is converted to a carboxylateCompoundRhea RHEA:10968Inferred only
an acyl-CoA is converted to a carboxylateCompoundRhea RHEA:24336Inferred only
an acyl-CoA is converted to a carboxylateCompoundRhea RHEA:70423Inferred only
a carboxylate is converted to an aldehydeCompoundRhea RHEA:16829Inferred only
an aldehyde is converted to a carboxylateCompoundRhea RHEA:16185Inferred only
an aldehyde is converted to a carboxylateCompoundRhea RHEA:16829Inferred only
a carboxylate is converted to an aldehydeCompoundRhea RHEA:50916Inferred only
an aldehyde is converted to a carboxylateCompoundRhea RHEA:50916Inferred only

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an aldehyde is converted to a carboxylateCompoundRhea RHEA:11888Inferred only
a carboxylate is metabolised by AOX1ProteinRhea RHEA:16829Inferred only
a carboxylate is metabolised by CES1ProteinRhea RHEA:21164Inferred only
a carboxylate is metabolised by CES2ProteinRhea RHEA:21164Inferred only
a carboxylate is metabolised by CES3ProteinRhea RHEA:21164Inferred only
a carboxylate is metabolised by CES5AProteinRhea RHEA:21164Inferred only
a carboxylate is a substrate of ACY1ProteinRhea RHEA:15565Inferred only
a carboxylate is a substrate of ACY3ProteinRhea RHEA:54184Inferred only
a carboxylate is a substrate of BCHEProteinRhea RHEA:21964Inferred only
a carboxylate is a substrate of FAHD1ProteinRhea RHEA:19009Inferred only
a carboxylate is a substrate of OVCA2ProteinRhea RHEA:21164Inferred only
a carboxylate is a substrate of PM20D1ProteinRhea RHEA:54184Inferred only
a carboxylate is a substrate of PM20D1ProteinRhea RHEA:15565Inferred only
a carboxylate is a substrate of PNKDProteinRhea RHEA:82919Inferred only
a carboxylate is transported by SLC22A13ProteinRhea RHEA:73487Inferred only

Reactions

52 reactions

an N-acyl-L-aspartate+watera carboxylate+L-aspartate
Catalysed by ASPA
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:10872CC BY 4.0Reference data
a carboxylate+GTP+coenzyme A(4-)an acyl-CoA+GDP+hydrogenphosphate
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:10968CC BY 4.0Reference data
an aldehyde+NADP(3-)+watera carboxylate+NADPH(4-)+2hydron
Catalysed by ALDH3B1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:11888CC BY 4.0Reference data
CHEBI:17503+waterCHEBI:29986+a carboxylate
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:12833CC BY 4.0Reference data
CHEBI:4194+an acyl phosphateCHEBI:140159+a carboxylate+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:13077CC BY 4.0Reference data
an acyl-CoA+acetatea carboxylate+acetyl-CoA
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:13381CC BY 4.0Reference data
an aldehyde+a quinone+watera quinol+a carboxylate+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:13881CC BY 4.0Reference data
an acyl phosphate+watera carboxylate+hydrogenphosphate+hydron
Catalysed by ACYP1 or ACYP2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:14965CC BY 4.0Reference data
an N-acyl-L-amino acid+wateran L-alpha-amino acid+a carboxylate
Catalysed by ACY1 or PM20D1
Reaction pageReversibleBalance undeterminable
Rhea RHEA:15565CC BY 4.0Reference data
an aldehyde+NAD(1-)+watera carboxylate+NADH(2-)+2hydron
Catalysed by ALDH1A1 or ALDH2 or ALDH1B1 or ALDH3A1 or ALDH3B1 or ALDH3B2 or ALDH9A1 or ALDH7A1 or ALDH3A2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:16185CC BY 4.0Reference data
an aldehyde+2oxidized [2Fe-2S]-[ferredoxin]+watera carboxylate+2reduced [2Fe-2S]-[ferredoxin]+3hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:16421CC BY 4.0Reference data
an aldehyde+dioxygen+watera carboxylate+hydrogen peroxide+hydron
Catalysed by AOX1
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:16829CC BY 4.0Reference data

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Other names

2 names

Resolves to: a carboxylate

Also called: carboxylic acid anionscarboxylic anions