Structure
No depiction stored
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- Class
- Organic compound, anion
- Formula
- C5H3N2O4
- Mass
- 155.089 g/mol
- Charge
- -1
- InChIKey
- PXQPEWDEAKTCGB-UHFFFAOYSA-M
- SMILES
- O=C([O-])c1cc(=O)nc(=O)n1
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
3 entities
3 entities reached.
What the reference databases state
Chemical structure
- orotate has the functional parent uracilCompoundChEBI CHEBI:30839Inferred only
Statements
9 statements
9 statements · 1 reference database · Subject: orotate · Sources: Rhea
- (S)-dihydroorotate is converted to orotateCompoundRhea RHEA:14861Inferred only
- orotate is converted to (S)-dihydroorotateCompoundRhea RHEA:13513Inferred only
- orotate is converted to (S)-dihydroorotateCompoundRhea RHEA:14861Inferred only
- (S)-dihydroorotate is converted to orotateCompoundRhea RHEA:13513Inferred only
- orotate is a substrate of DHODHProteinRhea RHEA:30187Inferred only
- orotate is a substrate of UMPSProteinRhea RHEA:10380Inferred only
- orotate is transported by SLC22A12ProteinRhea RHEA:72039Inferred only
- orotate is transported by SLC22A13ProteinRhea RHEA:73487Inferred only
- orotate is transported by SLC22A7ProteinRhea RHEA:72043Inferred only
Reactions
14 reactions
orotidine 5'-phosphate+diphosphate(3-)orotate+5-phospho-alpha-D-ribose 1-diphosphate
Catalysed by UMPS
Reaction pageRight to leftBalanced
Rhea RHEA:10380CC BY 4.0Reference data
(S)-dihydroorotate+NAD(1-)orotate+NADH(2-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:13513CC BY 4.0Reference data
(S)-dihydroorotate+NADP(3-)orotate+NADPH(4-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:14861CC BY 4.0Reference data
(S)-dihydroorotate+Aorotate+AH2
Reaction pageDirection not assertedBalanced
Rhea RHEA:18073CC BY 4.0Reference data
(S)-dihydroorotate+CHEBI:61683CHEBI:61682+orotate
Reaction pageDirection not assertedBalanced
Rhea RHEA:28687CC BY 4.0Reference data
(S)-dihydroorotate+a ubiquinoneorotate+a ubiquinol
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:28691CC BY 4.0Reference data
(S)-dihydroorotate+a menaquinoneorotate+a menaquinol
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:29195CC BY 4.0Reference data
(S)-dihydroorotate+CHEBI:44027orotate+CHEBI:61684
Reaction pageDirection not assertedBalanced
Rhea RHEA:29199CC BY 4.0Reference data
orotate+2hydronorotate+2hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:29347CC BY 4.0Reference data
(S)-dihydroorotate+fumaric acidorotate+succinate(2-)
Reaction pageDirection not assertedBalanced
Rhea RHEA:30059CC BY 4.0Reference data
(S)-dihydroorotate+a quinoneorotate+a quinol
Catalysed by DHODH
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:30187CC BY 4.0Reference data
orotate+nicotinateorotate+nicotinate
Transported by SLC22A12
Reaction pageDirection not assertedBalanced
Rhea RHEA:72039CC BY 4.0Reference data
Where it reaches
1 system, 1 region, 2 tissues, 2 transporter routes — routes, not measurements: transporters known to carry orotate are expressed there, and no source reports it arriving.
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Other names
1 name
Resolves to: orotate
- Systematic name
- 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate