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Proteins/UNIPROT:Q03154
Aminoacylase involved in the hydrolysis of N-acetylated and N-formylated amino acids. May act sequentially with APEH in the degradation of N-acylated peptides: APEH first cleaves N-acylaminoacids from N-acylated peptides, then ACY1 further hydrolyzes the N-acylaminoacid into free aminoacid and a carboxylate..
Function from UniProtKB (Q03154), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
108 statements
108 statements · 8 reference databases · Subject: ACY1 · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
7 reactions
water+MAM02540cacetate+L-methionine
Catalysed by ACY1
Reaction pageReversibleBalancedEC 3.5.1.14cytosol
Human-GEM MAR03919CC BY 4.0Reference data
water+MAM02530cacetate+L-alanine
Catalysed by ACY1
Reaction pageReversibleBalancedEC 3.5.1.14cytosol
Human-GEM MAR04199CC BY 4.0Reference data
2 names
Resolves to: ACY1
water+N(2)-acetyl-L-ornithineacetate+L-ornithine
Catalysed by ACY1
Reaction pageReversibleBalancedEC 3.5.1.14cytosol
Human-GEM MAR08425CC BY 4.0Reference data
an N-acyl-L-amino acid+wateran L-alpha-amino acid+a carboxylate
Reaction pageReversibleBalance undeterminable
Rhea RHEA:15565CC BY 4.0Reference data
N(alpha)-formyl-L-methionine+waterformate+L-methionine
Catalysed by ACY1
Reaction pageLeft to rightBalanced
Rhea RHEA:17781CC BY 4.0Reference data
N-acetyl-L-glutamine+waterL-glutamine+acetate
Catalysed by ACY1
Reaction pageLeft to rightBalanced
Rhea RHEA:67368CC BY 4.0Reference data
N-acetyl-L-methionine+waterL-methionine+acetate
Reaction pageLeft to rightBalanced
Rhea RHEA:67440CC BY 4.0Reference data