(3S)-citramalyl-CoA

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA

Catalysed by CLYBL

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. transport of 2-hydroxybutyrate and pyruvate (cytosol to extracellular)

Catalysed by CLYBL, SLC16A4, SLC16A5, SLC16A3 and 3 moreextracellular space, cytosolOne of 2 routes

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. transport of acetoacetate and pyruvate (cytosol to mitochondria)

Catalysed by CLYBLmitochondrial matrix, cytosolOne of 4 routes

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. acetylpyruvate + H2O = acetate + pyruvate + H(+)

Catalysed by CLYBL, FAHD1

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. transport of pyruvate and retinoate (cytosol to extracellular)

Catalysed by CLYBL, SLC16A4, SLC16A5, SLC16A3 and 3 moreextracellular space, cytosolOne of 2 routes

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. (S)-malate + NAD(+) = pyruvate + CO2 + NADH

Catalysed by CLYBL, ME2One of 2 routes

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase

Catalysed by CLYBL, AGXT2mitochondrial matrix

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. Pyruvate:carbon-dioxide ligase (ADP-forming)

Catalysed by CLYBL, PCmitochondrial matrixOne of 3 routes

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. (S)-lactate + NAD(+) = pyruvate + NADH + H(+)

Catalysed by CLYBL, LDHA, LDHB, LDHC and 2 more

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. 2-oxobutanoate + L-alanine = (2S)-2-aminobutanoate + pyruvate

Catalysed by CLYBL, AGXT2

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. L-Glutamine:pyruvate aminotransferase

Catalysed by CLYBL, KYAT1cytosolOne of 2 routes

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. 3-fumarylpyruvate + H2O = fumarate + pyruvate + H(+)

Catalysed by CLYBL, FAHD1

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. transport of (R)-3-hydroxybutanoate and pyruvate (cytosol to extracellular)

Catalysed by CLYBL, SLC16A4, SLC16A5, SLC16A3 and 3 moreextracellular space, cytosolOne of 2 routes

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. L-serine + pyruvate = 3-hydroxypyruvate + L-alanine

Catalysed by CLYBL, AGXT

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. aceneuramate = aldehydo-N-acetyl-D-mannosamine + pyruvate

Catalysed by CLYBL, NPL

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. N(1)-methylguanosine(37) in tRNA(Phe) + pyruvate + S-adenosyl-L-methionine = 4-demethylwyosine(37) in tRNA(Phe) + 5'-deoxyadenosine + L-methionine + CO2 + H2O

Catalysed by CLYBL, TYW1B, TYW1

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. pyruvate kinase (dTDP)

Catalysed by CLYBL, PKM, PKLRcytosol

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. N(omega),N(omega)-dimethyl-L-arginine + pyruvate = 5-(3,3-dimethylguanidino)-2-oxopentanoate + L-alanine

Catalysed by CLYBL, AGXT2

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. N(omega),N('omega)-dimethyl-L-arginine + pyruvate = 5-(3,3'-dimethylguanidino)-2-oxopentanoate + L-alanine

Catalysed by CLYBL, AGXT2

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. N(omega)-methyl-L-arginine + pyruvate = 5-(3-methylguanidino)-2-oxopentanoate + L-alanine

Catalysed by CLYBL, AGXT2

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. transport of acetate and pyruvate (cytosol to extracellular)

Catalysed by CLYBL, SLC16A4, SLC16A5, SLC16A3 and 2 moreextracellular space, cytosolOne of 2 routes

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. transport of formate and pyruvate (cytosol to extracellular)

Catalysed by CLYBL, SLC16A4, SLC16A5, SLC16A7 and 2 moreextracellular space, cytosolOne of 2 routes

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. transport of propanoate and pyruvate (cytosol to extracellular)

Catalysed by CLYBL, SLC16A4, SLC16A5, SLC16A3 and 3 moreextracellular space, cytosolOne of 2 routes

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. transport of butyrate and pyruvate (cytosol to extracellular)

Catalysed by CLYBL, SLC16A4, SLC16A5, SLC16A3 and 3 moreextracellular space, cytosolOne of 2 routes

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. L-Serine:pyruvate aminotransferase

Catalysed by CLYBL, AGXTcytosolOne of 2 routes

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. 3-oxopropanoate + L-alanine = beta-alanine + pyruvate

Catalysed by CLYBL, AGXT2

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. D-serine = pyruvate + NH4(+)

Catalysed by CLYBL, SRR

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. (R)-Lactate:NAD+ oxidoreductase

Catalysed by CLYBL, LDHDcytosol

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. (S)-Lactate:NAD+ oxidoreductase

Catalysed by CLYBL, LDHB, LDHAL6Bmitochondrial matrixOne of 5 routes

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. 2-iminopropanoate + H2O = pyruvate + NH4(+)

Catalysed by CLYBL, RIDA

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. pyruvate kinase (dTDP)

Catalysed by CLYBL, PKM, PKLRcytosol

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. N-Acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)

Catalysed by CLYBL, NPLcytosol

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. a 3-acylpyruvate + H2O = a carboxylate + pyruvate + H(+)

Catalysed by CLYBL, FAHD1

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. 2-oxo-3-sulfanylpropanoate + [thioredoxin]-dithiol = [thioredoxin]-disulfide + hydrogen sulfide + pyruvate + H(+)

Catalysed by CLYBL, MPST

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. (R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine

Catalysed by CLYBL, AGXT2

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. N(1)-methylguanosine(37) in tRNA(Phe) + pyruvate + S-adenosyl-L-methionine = 4-demethylwyosine(37) in tRNA(Phe) + 5'-deoxyadenosine + L-methionine + CO2 + H2O

Catalysed by CLYBL, TYW1B, TYW1

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase

Catalysed by CLYBL, AGXT2mitochondrial matrixOne of 18 routes

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine

Catalysed by CLYBL, AGXT2

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. (4R)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate

Catalysed by CLYBL, HOGA1

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. (4S)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate

Catalysed by CLYBL, HOGA1

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. pyruvate:thiamin diphosphate acetaldehydetransferase (decarboxylating)

Catalysed by CLYBL, PDHA1, PDHB, PDHA2mitochondrial matrix

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. transport of acetoacetate and pyruvate (cytosol to mitochondria)
3. (S)-3-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + acetoacetate

Catalysed by CLYBL, ADHFE1mitochondrial matrix, cytosol

1. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
2. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
3. amino-acid N-acetyltransferase (N-acetyl-L-alanine)

Catalysed by CLYBL,