orotate

1. (S)-dihydroorotate + a quinone = orotate + a quinol

Catalysed by DHODH

1. orotate(out) + a carboxylate(in) = orotate(in) + a carboxylate(out)

Catalysed by SLC22A13inner side of the membrane, outer side of the membraneOne of 2 routes

1. (S)-dihydroorotate + a quinone = orotate + a quinol

Catalysed by DHODH

1. orotate(out) + nicotinate(in) = orotate(in) + nicotinate(out)

Catalysed by SLC22A12inner side of the membrane, outer side of the membraneOne of 2 routes

1. orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate

Catalysed by UMPS

1. (S)-dihydroorotate + a quinone = orotate + a quinol
2. 2 a quinone + NADPH + H(+) = 2 a 1,4-benzosemiquinone + NADP(+)

Catalysed by DHODH, CRYZ, TP53I3, VAT1 and 1 more

1. orotate(out) + a carboxylate(in) = orotate(in) + a carboxylate(out)
2. an N-acyl-aromatic L-alpha-amino acid + H2O = an aromatic L-alpha-amino acid + a carboxylate

Catalysed by SLC22A13, PM20D1, ACY3inner side of the membrane, outer side of the membrane

1. (S)-dihydroorotate + a quinone = orotate + a quinol
2. a quinone + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + a quinol
3. beta-D-fructose 1-phosphate = D-glyceraldehyde + dihydroxyacetone phosphate

Catalysed by DHODH, GPD2, ALDOB

1. orotate(out) + a carboxylate(in) = orotate(in) + a carboxylate(out)
2. an acylcholine + H2O = a carboxylate + choline + H(+)
3. an acylcholine + H2O = a carboxylate + choline + H(+)

Catalysed by SLC22A13,