Compound
(4S)-4-hydroxy-2-oxoglutarate
An optically active form of 4-hydroxy-2-oxoglutarate(2−) having L-configuration.
Definition from ChEBI (CHEBI:71685), read 2026-09-23. CC BY 4.0.
Structure
Loading the model…
- Class
- Organic compound, anion
- Formula
- C5H4O6
- Mass
- 160.081 g/mol
- Charge
- -2
- InChIKey
- WXSKVKPSMAHCSG-REOHCLBHSA-L
- SMILES
- O=C([O-])C(=O)C[C@H](O)C(=O)[O-]
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
1 entity
1 entities reached.
0 reported hops1 assembled from the scaffold
What the reference databases state
Statements
1 statement
1 statement · 1 reference database · Subject: (4S)-4-hydroxy-2-oxoglutarate · Sources: Rhea
- (4S)-4-hydroxy-2-oxoglutarate is a substrate of HOGA1ProteinRhea RHEA:35639Inferred only
Reactions
3 reactions
(4S)-4-hydroxy-2-oxoglutarateglyoxylate+pyruvate
Catalysed by HOGA1
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:35639CC BY 4.0Reference data
(4S)-4-hydroxy-2-oxoglutarate+NAD(1-)+coenzyme A(4-)(S)-malyl-CoA+carbon dioxide+NADH(2-)
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:86299CC BY 4.0Reference data
(4S)-4-hydroxy-2-oxoglutarate+N(6)-[(R)-lipoyl]-L-lysyl-[protein]+hydronN(6)-[(R)-S(8)-((S)-malyl)dihydrolipoyl]-L-lysyl-[protein]+carbon dioxide
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:86323CC BY 4.0Reference data
Other names
2 names
Resolves to: (4S)-4-hydroxy-2-oxoglutarate
- Also called
- (S)-2-hydroxy-4-oxopentanedioate
- Systematic name
- (2S)-2-hydroxy-4-oxopentanedioate