Compound

(4R)-4-hydroxy-2-oxoglutarate

A 4-hydroxy-2-oxoglutarate(2−) having D-configuration.

Definition from ChEBI (CHEBI:62213), read 2026-09-23. CC BY 4.0.

CHEBI:62213ChEBI

Open in the graph

Structure

2D depiction · 3D model shown

Loading the model…

A generated conformer of (4R)-4-hydroxy-2-oxoglutarate — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, anion
Formula: C5H4O6
Mass: 160.081 g/mol
Charge: -2
InChIKey: WXSKVKPSMAHCSG-UWTATZPHSA-L
SMILES: O=C([O-])C(=O)C[C@@H](O)C(=O)[O-]
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

1 entity

1 entities reached.

0 reported hops1 assembled from the scaffold

HOGA1ProteinUNIPROT:Q86XE5substrate ofInferred only4 paths4 endpoints

What the reference databases state

Statements

1 statement

1 statement · 1 reference database · Subject: (4R)-4-hydroxy-2-oxoglutarate · Sources: Rhea

Order

(4R)-4-hydroxy-2-oxoglutarate is a substrate of HOGA1ProteinRhea RHEA:30687Inferred only

Reactions

2 reactions

(4R)-4-hydroxy-2-oxoglutarateglyoxylate+pyruvate
Catalysed by HOGA1
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:30687CC BY 4.0Reference data
CHEBI:6331+2-oxoglutarate(2-)(4R)-4-hydroxy-2-oxoglutarate+L-glutamate(1-)
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:31235CC BY 4.0Reference data

Other names

4 names

Resolves to: (4R)-4-hydroxy-2-oxoglutarate

Also called: (R)-2-hydroxy-4-oxopentanedioateD-4-hydroxy-2-ketoglutarateD-4-hydroxy-2-oxoglutarate dianion
Systematic name: (2R)-2-hydroxy-4-oxopentanedioate