phosphoenolpyruvic acid

1. GTP:pyruvate 2-O-phosphotransferase
2. (R)-Lactate:NAD+ oxidoreductase

Catalysed by PKM, PKLR, LDHDcytosol

1. GTP:pyruvate 2-O-phosphotransferase
2. (S)-Lactate:NAD+ oxidoreductase

Catalysed by PKM, PKLR, LDHB, LDHAL6Bcytosol, mitochondrial matrixOne of 5 routes

1. GTP:pyruvate 2-O-phosphotransferase
2. 2-iminopropanoate + H2O = pyruvate + NH4(+)

Catalysed by PKM, PKLR, RIDAcytosol

1. GTP:pyruvate 2-O-phosphotransferase
2. N-Acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)

Catalysed by PKM, PKLR, NPLcytosolOne of 2 routes

1. GTP:pyruvate 2-O-phosphotransferase
2. a 3-acylpyruvate + H2O = a carboxylate + pyruvate + H(+)

Catalysed by PKM, PKLR, FAHD1cytosol

1. dGTP:pyruvate 2-O-phosphotransferase
2. 2-Deoxyguanosine 5-Triphosphate Pyrophosphohydrolase

Catalysed by PKM, PKLR, ITPAcytosol, extracellular space

1. GTP:pyruvate 2-O-phosphotransferase
2. 2-oxo-3-sulfanylpropanoate + [thioredoxin]-dithiol = [thioredoxin]-disulfide + hydrogen sulfide + pyruvate + H(+)

Catalysed by PKM, PKLR, MPSTcytosol

1. GTP:pyruvate 2-O-phosphotransferase
2. (R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine

Catalysed by PKM, PKLR, AGXT2cytosol

1. GTP:pyruvate 2-O-phosphotransferase
2. N(1)-methylguanosine(37) in tRNA(Phe) + pyruvate + S-adenosyl-L-methionine = 4-demethylwyosine(37) in tRNA(Phe) + 5'-deoxyadenosine + L-methionine + CO2 + H2O

Catalysed by PKM, PKLR, TYW1B, TYW1cytosol

1. GTP:pyruvate 2-O-phosphotransferase
2. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase

Catalysed by PKM, PKLR, AGXT2cytosol, mitochondrial matrixOne of 18 routes

1. 2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming)
2. D-phosphoglycerate 2,3-phosphomutase

Catalysed by ENO1, ENO2, ENO3, BPGM and 3 morecytosolOne of 2 routes

1. dATP:pyruvate 2-O-phosphotransferase
2. cytidine/uridine monophosphate kinase (dADP)

Catalysed by PKM, PKLR, CMPK1cytosolOne of 4 routes

1. GTP:pyruvate 2-O-phosphotransferase
2. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA

Catalysed by PKM, PKLR, CLYBLcytosol

1. 2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming)
2. (2R)-2-phosphoglycerate = phosphoenolpyruvate + H2O

Catalysed by ENO1, ENO2, ENO3, ENO4cytosolOne of 3 routes

1. GTP:pyruvate 2-O-phosphotransferase
2. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine

Catalysed by PKM, PKLR, AGXT2cytosol

1. GTP:pyruvate 2-O-phosphotransferase
2. (4R)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate

Catalysed by PKM, PKLR, HOGA1cytosol

1. pyruvate kinase (dTDP)
2. dTTP + H2O = dTMP + diphosphate + H(+)

Catalysed by PKM, PKLR, ASMTLcytosol

1. GTP:pyruvate 2-O-phosphotransferase
2. (4S)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate

Catalysed by PKM, PKLR, HOGA1cytosol

1. transport of citrate and PEP (cytosol to mitochondria)
2. citrate + L-glutamate + ATP = beta-citrylglutamate + ADP + phosphate + H(+)

Catalysed by SLC25A1, RIMKLBmitochondrial matrix, cytosol

1. dATP:pyruvate 2-O-phosphotransferase
2. Antiport of thiamine-diphosphate and dATP

Catalysed by PKM, PKLR, SLC25A19cytosol, mitochondrial matrixOne of 2 routes

1. GTP:pyruvate 2-O-phosphotransferase
2. pyruvate:thiamin diphosphate acetaldehydetransferase (decarboxylating)

Catalysed by PKM, PKLR, PDHA1, PDHB and 1 morecytosol, mitochondrial matrix

1. GTP:pyruvate 2-O-phosphotransferase
2. transport of acetoacetate and pyruvate (cytosol to mitochondria)
3. (S)-3-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + acetoacetate

Catalysed by PKM, PKLR, ADHFE1cytosol, mitochondrial matrix

1. GTP:pyruvate 2-O-phosphotransferase
2. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
3. amino-acid N-acetyltransferase (N-acetyl-L-alanine)

Catalysed by