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Proteins/UNIPROT:Q86V21
Converts acetoacetate to acetoacetyl-CoA in the cytosol (By similarity). Ketone body-utilizing enzyme, responsible for the synthesis of cholesterol and fatty acids (By similarity)..
Function from UniProtKB (Q86V21), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
33 statements
33 statements · 6 reference databases · Subject: AACS · Sources: Bgee, gene ontology, Hetionet, Human-GEM, Reactome, Rhea
3 reactions
acetoacetate+ATP+CHEBI:1146900CHEBI:15345+AMP+diphosphate(3-)
Catalysed by AACS
Reaction pageLeft to rightBalancedEC 6.2.1.16cytosol
Human-GEM MAR01436CC BY 4.0Reference data
4 names
Resolves to: AACS
Catalysed by AACS
Reaction pageLeft to rightBalancedEC 6.2.1.16mitochondrial matrix
Human-GEM MAR01576CC BY 4.0Reference data
acetoacetate+ATP(4-)+coenzyme A(4-)acetoacetyl-CoA+AMP+diphosphate(3-)
Catalysed by AACS
Reaction pageLeft to rightBalanced
Rhea RHEA:16117CC BY 4.0Reference data