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Proteins/UNIPROT:P30085
Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity..
Function from UniProtKB (P30085), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
270 statements
270 statements · 7 reference databases · Subject: CMPK1 · Sources: Bgee, Hetionet, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
45 reactions
CHEBI:17239+GDPcytidine 5'-monophosphate+GTP
Catalysed by CMPK1
Reaction pageReversibleBalancedEC 2.7.4.14cytosol
Human-GEM MAR03967CC BY 4.0Reference data
Catalysed by CMPK1
Reaction pageReversibleBalancedEC 2.7.4.14, 2.7.4.4cytosol
12 names
Resolves to: CMPK1
ADP+CHEBI:17239ATP+cytidine 5'-monophosphate
Catalysed by CMPK1
Reaction pageReversibleBalancedEC 2.7.4.14, 2.7.4.25cytosol
Human-GEM MAR04024CC BY 4.0Reference data
Catalysed by CMPK1
Reaction pageReversibleBalancedEC 2.7.4.14cytosol
Human-GEM MAR04512CC BY 4.0Reference data
CHEBI:17239+UDPCHEBI:17677+UMP
Catalysed by CMPK1
Reaction pageReversibleBalancedEC 2.7.4.14cytosol
Human-GEM MAR07863CC BY 4.0Reference data
CHEBI:17239+UDPCHEBI:17677+UMP
Catalysed by CMPK1
Reaction pageReversibleBalancedEC 2.7.4.14nucleus
Human-GEM MAR07864CC BY 4.0Reference data
Catalysed by CMPK1
Reaction pageReversibleBalancedEC 2.7.4.14cytosol
Human-GEM MAR07865CC BY 4.0Reference data
Catalysed by CMPK1
Reaction pageReversibleBalancedEC 2.7.4.14nucleus
Human-GEM MAR07866CC BY 4.0Reference data
Catalysed by CMPK1
Reaction pageReversibleBalancedEC 2.7.4.14cytosol
Human-GEM MAR07867CC BY 4.0Reference data
Catalysed by CMPK1
Reaction pageReversibleBalancedEC 2.7.4.14nucleus
Human-GEM MAR07868CC BY 4.0Reference data
CHEBI:16174+UDPCHEBI:16284+UMP
Catalysed by CMPK1
Reaction pageReversibleBalancedEC 2.7.4.14cytosol
Human-GEM MAR07869CC BY 4.0Reference data
CHEBI:16174+UDPCHEBI:16284+UMP
Catalysed by CMPK1
Reaction pageReversibleBalancedEC 2.7.4.14nucleus
Human-GEM MAR07870CC BY 4.0Reference data