L-leucine

1. Acetylation of Leucine

No catalyst recordedmitochondrial matrix

1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate

Catalysed by PM20D1

1. Chymase

Catalysed by CMA1extracellular spaceOne of 2 routes

1. transport of homoserine and leucine (cytosol to extracellular)

Catalysed by SLC7A5extracellular space, cytosolOne of 3 routes

1. solute carrier (L-dopa)

Catalysed by SLC3A2, SLC7A5extracellular space, cytosol

1. transport of histidine and leucine (cytosol to extracellular)

Catalysed by SLC7A6extracellular space, cytosolOne of 2 routes

1. Transport of L-Cystine (L-Leucine antiport) by B0, +At Transporter

Catalysed by SLC7A9, SLC3A1extracellular space, cytosol

1. transport of citrulline and leucine (cytosol to extracellular)

No catalyst recordedextracellular space, cytosolOne of 2 routes

1. transport of leucine and valine (cytosol to extracellular)

Catalysed by SLC7A5extracellular space, cytosolOne of 4 routes

1. transport of arginine and leucine (cytosol to extracellular)

Catalysed by SLC3A2, SLC7A6, SLC7A7extracellular space, cytosolOne of 6 routes

1. PROTEIN_BS

No catalyst recordedcytosol

1. transport of leucine and threonine (cytosol to extracellular)

Catalysed by SLC7A5extracellular space, cytosolOne of 4 routes

1. transport of isoleucine and leucine (cytosol to extracellular)

Catalysed by SLC7A5extracellular space, cytosolOne of 3 routes

1. transport of leucine and proline (cytosol to extracellular)

Catalysed by SLC7A5extracellular space, cytosolOne of 3 routes

1. transport of cysteine and leucine (cytosol to extracellular)

Catalysed by SLC7A9, SLC3A1extracellular space, cytosolOne of 3 routes

1. L-Leucine:2-oxoglutarate aminotransferase

Catalysed by BCAT2mitochondrial matrixOne of 4 routes

1. transport of leucine and tyrosine (cytosol to extracellular)

Catalysed by SLC7A5extracellular space, cytosolOne of 4 routes

1. transport of leucine and lysine (cytosol to extracellular)

Catalysed by SLC7A6extracellular space, cytosolOne of 2 routes

1. transport of glutamine and leucine (cytosol to extracellular)

Catalysed by SLC7A5extracellular space, cytosolOne of 4 routes

1. S-methylmercury-L-cysteine(in) + L-leucine(out) = S-methylmercury-L-cysteine(out) + L-leucine(in)

Catalysed by SLC7A8inner side of the membrane, outer side of the membraneOne of 2 routes

1. transport of chloride and leucine (cytosol to extracellular)

Catalysed by SLC6A14extracellular space, cytosolOne of 2 routes

1. L-leucine(out) + L-aspartate(in) = L-leucine(in) + L-aspartate(out)

Catalysed by SLC7A13inner side of the membrane, outer side of the membraneOne of 2 routes

1. L-lysine(in) + L-leucine(out) + Na(+)(out) = L-lysine(out) + L-leucine(in) + Na(+)(in)

Catalysed by SLC7A7inner side of the membrane, outer side of the membraneOne of 2 routes

1. transport of leucine and ornithine (cytosol to extracellular)

Catalysed by SLC7A6extracellular space, cytosolOne of 4 routes

1. transport of glycine and leucine (cytosol to extracellular)

Catalysed by SLC7A5extracellular space, cytosolOne of 5 routes

1. transport of leucine and methionine (cytosol to extracellular)

Catalysed by SLC3A2, SLC7A5extracellular space, cytosolOne of 6 routes

1. transport of leucine and tryptophan (cytosol to extracellular)

Catalysed by SLC7A5extracellular space, cytosolOne of 4 routes

1. Transport of L-Kynurenine

Catalysed by SLC43A1extracellular space, cytosolOne of 2 routes

1. transport of alanine and leucine (cytosol to extracellular)

Catalysed by SLC7A5extracellular space, cytosolOne of 4 routes

1. transport of asparagine and leucine (cytosol to extracellular)

Catalysed by SLC7A5extracellular space, cytosolOne of 3 routes

1. transport of leucine and phenylalanine (cytosol to extracellular)

Catalysed by SLC7A5extracellular space, cytosolOne of 6 routes

1. transport of leucine and tryptophan (cytosol to extracellular)
2. beta-carboline hydrolysis

Catalysed by SLC7A5extracellular space, cytosol

1. transport of chloride and leucine (cytosol to extracellular)
2. Carnitine Transport by Atb0

Catalysed by SLC6A14extracellular space, cytosolOne of 245 routes