Compound
dGMP
A 2'-deoxyribonucleoside 5'-monophosphate(2−) obtained by deprotonation of the phosphate OH groups of 2'-deoxyguanosine 5'-monophosphate (dGMP).
Definition from ChEBI (CHEBI:57673), read 2026-09-23. CC BY 4.0.
Structure
No depiction stored
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- Class
- Organic compound, anion
- Formula
- C10H12N5O7P
- Mass
- 345.208 g/mol
- Charge
- -2
- InChIKey
- LTFMZDNNPPEQNG-KVQBGUIXSA-L
- SMILES
- Nc1nc(=O)c2ncn([C@H]3C[C@H](O)[C@@H](COP(=O)([O-])[O-])O3)c2n1
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
14 entities
14 entities reached.
0 reported hops14 assembled from the scaffold
- SLC25A36ProteinUNIPROT:Q96CQ1transported byInferred only78 paths39 endpoints
- NT5C2ProteinUNIPROT:P49902substrate ofInferred only36 paths12 endpoints
- NT5EProteinUNIPROT:P21589substrate ofInferred only21 paths21 endpoints
- NT5CProteinUNIPROT:Q8TCD5substrate ofInferred only16 paths8 endpoints
- DCKProteinUNIPROT:P27707substrate ofInferred only11 paths11 endpoints
- GUK1ProteinUNIPROT:Q16774substrate ofInferred only8 paths8 endpoints
- DGUOKProteinUNIPROT:Q16854substrate ofInferred only7 paths7 endpoints
- NT5C1AProteinUNIPROT:Q9BXI3substrate ofInferred only5 paths5 endpoints
- ACP3ProteinUNIPROT:P15309substrate ofInferred only5 paths5 endpoints
- NT5C1BProteinUNIPROT:Q96P26substrate ofInferred only4 paths4 endpoints
- NT5C3AProteinUNIPROT:Q9H0P0substrate ofInferred only4 paths4 endpoints
- NT5MProteinUNIPROT:Q9NPB1substrate ofInferred only4 paths4 endpoints
What the reference databases state
Statements
37 statements
37 statements · 2 reference databases · Subject: dGMP · Sources: Human-GEM, Rhea
- dGMP is converted to 2'-deoxyguanosineCompoundRhea RHEA:19201Inferred only
- dGMP is converted to 2'-deoxyguanosineCompoundHuman-GEM MAR04602Inferred only
- dGMP is converted to 2'-deoxyguanosineCompoundHuman-GEM MAR08495Inferred only
- dGMP is converted to 2'-deoxyguanosineCompoundRhea RHEA:29379Inferred only
- 2'-deoxyguanosine is converted to dGMPCompoundHuman-GEM MAR04600Inferred only
- 2'-deoxyguanosine is converted to dGMPCompoundHuman-GEM MAR04601Inferred only
- 2'-deoxyguanosine is converted to dGMPCompoundRhea RHEA:19201Inferred only
- CHEBI:16497 is converted to dGMPCompoundHuman-GEM MAR02120Inferred only
- CHEBI:28862 is converted to dGMPCompoundHuman-GEM MAR05353Inferred only
- dGMP is converted to CHEBI:28862CompoundHuman-GEM MAR05353Inferred only
- dGDP is converted to dGMPCompoundRhea RHEA:64940Inferred only
- dGMP is converted to dGDPCompoundRhea RHEA:12697Inferred only
Show the remaining 25
- dGDP is converted to dGMPCompoundRhea RHEA:62136Inferred only
- dGDP is converted to dGMPCompoundRhea RHEA:12697Inferred only
- dGMP is converted to dGDPCompoundRhea RHEA:62136Inferred only
- dGTP is converted to dGMPCompoundRhea RHEA:64932Inferred only
- dGMP is converted to dGTPCompoundRhea RHEA:64932Inferred only
- dGTP is converted to dGMPCompoundRhea RHEA:28362Inferred only
- dGMP is a substrate of ACP2ProteinHuman-GEM MAR08495Inferred only
- dGMP is a substrate of ACP3ProteinHuman-GEM MAR04602Inferred only
- dGMP is a substrate of DCKProteinRhea RHEA:19201Inferred only
- dGMP is a substrate of DGUOKProteinRhea RHEA:19201Inferred only
- dGMP is a substrate of GUK1ProteinHuman-GEM MAR05353Inferred only
- dGMP is a substrate of NT5CProteinHuman-GEM MAR04602Inferred only
- dGMP is a substrate of NT5CProteinRhea RHEA:29379Inferred only
- dGMP is a substrate of NT5C1AProteinHuman-GEM MAR04602Inferred only
- dGMP is a substrate of NT5C1BProteinHuman-GEM MAR04602Inferred only
- dGMP is a substrate of NT5C2ProteinHuman-GEM MAR04602Inferred only
- dGMP is a substrate of NT5C2ProteinRhea RHEA:29379Inferred only
- dGMP is a substrate of NT5C2ProteinRhea RHEA:69580Inferred only
- dGMP is a substrate of NT5C3AProteinHuman-GEM MAR04602Inferred only
- dGMP is a substrate of NT5C3BProteinHuman-GEM MAR04602Inferred only
- dGMP is a substrate of NT5EProteinHuman-GEM MAR04602Inferred only
- dGMP is a substrate of NT5MProteinRhea RHEA:29379Inferred only
- dGMP is a substrate of RBAKProteinHuman-GEM MAR04602Inferred only
- dGMP is transported by SLC25A36ProteinRhea RHEA:73635Inferred only
- dGMP is transported by SLC25A36ProteinHuman-GEM MAR20142Inferred only
Reactions
29 reactions
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR01912CC BY 4.0Reference data
CHEBI:16497+waterdGMP+proton+diphosphate(3-)
Catalysed by ITPA
Reaction pageLeft to rightBalancedEC 3.6.1.9extracellular space
Human-GEM MAR02120CC BY 4.0Reference data
ATP+2'-deoxyguanosineADP+dGMP+proton
Catalysed by DGUOK
Reaction pageLeft to rightBalancedEC 2.7.1.113cytosol
Human-GEM MAR04600CC BY 4.0Reference data
ATP+2'-deoxyguanosineADP+dGMP+proton
Catalysed by DGUOK
Reaction pageLeft to rightBalancedEC 2.7.1.113mitochondrial matrix
Human-GEM MAR04601CC BY 4.0Reference data
dGMP+water2'-deoxyguanosine+phosphate(3-)
Catalysed by ACP3 or NT5C2 or NT5C1A or NT5C3A or NT5C or NT5E or NT5C3B or RBAK or NT5C1B
Reaction pageLeft to rightBalancedEC 3.1.3.5cytosol
Human-GEM MAR04602CC BY 4.0Reference data
Reaction pageLeft to rightBalancedmitochondrial matrix, cytosol
Human-GEM MAR04998CC BY 4.0Reference data
Catalysed by GUK1
Reaction pageReversibleBalancedEC 2.7.4.8cytosol
Human-GEM MAR05353CC BY 4.0Reference data
MAM01721n+water0.3MAM01639n+0.2dCMP+0.2dGMP+0.3dTMP+proton
Catalysed by RAD1 & RAD9A or TREX2 or TREX1
Reaction pageLeft to rightBalance undeterminableEC 3.1.11.2nucleus
Human-GEM MAR07163CC BY 4.0Reference data
CHEBI:16174+CHEBI:28862CHEBI:16284+dGMP
Reaction pageReversibleBalancedmitochondrial matrix
Human-GEM MAR08481CC BY 4.0Reference data
Reaction pageReversibleBalancedcytosol, lysosome
Human-GEM MAR08492CC BY 4.0Reference data
dGMP+water2'-deoxyguanosine+phosphate(3-)
Catalysed by ACP2
Reaction pageLeft to rightBalancedEC 3.1.3.2lysosome
Human-GEM MAR08495CC BY 4.0Reference data
Reaction pageReversibleBalancedcytosol, nucleus
Human-GEM MAR13085CC BY 4.0Reference data
Where it reaches
7 systems, 13 regions, 39 tissues, 39 transporter routes — routes, not measurements: transporters known to carry dGMP are expressed there, and no source reports it arriving.
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Other names
4 names
Resolves to: dGMP
- Also called
- dGMP dianiondGMP(2-)dGMP(2−)
- Systematic name
- 2'-deoxy-5'-O-phosphonatoguanosine