Compound
phosphoenolpyruvate
A monocarboxylic acid anion derived from selective deprotonation of the carboxy group of phosphoenolpyruvic acid. It is a metabolic intermediate in glycolysis; gluconeogenesis; and other pathways.
Structure
Loading the model…
- Class
- Organic compound, anion
- Formula
- C3H2O6P
- Mass
- 165.017 g/mol
- Charge
- -3
- InChIKey
- DTBNBXWJWCWCIK-UHFFFAOYSA-K
- SMILES
- C=C(OP(=O)([O-])[O-])C(=O)[O-]
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
10 entities
10 entities reached.
0 reported hops10 assembled from the scaffold
- ENO1ProteinUNIPROT:P06733substrate ofInferred only75 paths75 endpoints
- PKMProteinUNIPROT:P14618substrate ofInferred only66 paths65 endpoints
- PCK1ProteinUNIPROT:P35558substrate ofInferred only42 paths42 endpoints
- ENO2ProteinUNIPROT:P09104substrate ofInferred only35 paths35 endpoints
- SLC25A1ProteinUNIPROT:P53007transported byInferred only28 paths28 endpoints
- ENO3ProteinUNIPROT:P13929substrate ofInferred only17 paths17 endpoints
- PCK2ProteinUNIPROT:Q16822substrate ofInferred only13 paths13 endpoints
- NANSProteinUNIPROT:Q9NR45substrate ofInferred only12 paths6 endpoints
- PKLRProteinUNIPROT:P30613substrate ofInferred only11 paths11 endpoints
- ENO4ProteinUNIPROT:A6NNW6substrate ofInferred only5 paths5 endpoints
What the reference databases state
Statements
34 statements
34 statements · 1 reference database · Subject: phosphoenolpyruvate · Sources: Rhea
- phosphoenolpyruvate is converted to (2R)-2-phosphoglycerateCompoundRhea RHEA:10164Inferred only
- (2R)-2-phosphoglycerate is converted to phosphoenolpyruvateCompoundRhea RHEA:10164Inferred only
- phosphoenolpyruvate is converted to oxaloacetateCompoundRhea RHEA:22356Inferred only
- phosphoenolpyruvate is converted to oxaloacetateCompoundRhea RHEA:28370Inferred only
- oxaloacetate is converted to phosphoenolpyruvateCompoundRhea RHEA:18617Inferred only
- oxaloacetate is converted to phosphoenolpyruvateCompoundRhea RHEA:10388Inferred only
- oxaloacetate is converted to phosphoenolpyruvateCompoundRhea RHEA:28370Inferred only
- phosphoenolpyruvate is converted to oxaloacetateCompoundRhea RHEA:10388Inferred only
- oxaloacetate is converted to phosphoenolpyruvateCompoundRhea RHEA:22356Inferred only
- phosphoenolpyruvate is converted to oxaloacetateCompoundRhea RHEA:18617Inferred only
- pyruvate is converted to phosphoenolpyruvateCompoundRhea RHEA:56952Inferred only
- phosphoenolpyruvate is converted to pyruvateCompoundRhea RHEA:10756Inferred only
Show the remaining 22
- phosphoenolpyruvate is converted to pyruvateCompoundRhea RHEA:11364Inferred only
- phosphoenolpyruvate is converted to pyruvateCompoundRhea RHEA:18157Inferred only
- phosphoenolpyruvate is converted to pyruvateCompoundRhea RHEA:19997Inferred only
- phosphoenolpyruvate is converted to pyruvateCompoundRhea RHEA:30295Inferred only
- phosphoenolpyruvate is converted to pyruvateCompoundRhea RHEA:56948Inferred only
- phosphoenolpyruvate is converted to pyruvateCompoundRhea RHEA:56952Inferred only
- pyruvate is converted to phosphoenolpyruvateCompoundRhea RHEA:10756Inferred only
- pyruvate is converted to phosphoenolpyruvateCompoundRhea RHEA:11364Inferred only
- pyruvate is converted to phosphoenolpyruvateCompoundRhea RHEA:19997Inferred only
- pyruvate is converted to phosphoenolpyruvateCompoundRhea RHEA:30295Inferred only
- pyruvate is converted to phosphoenolpyruvateCompoundRhea RHEA:56948Inferred only
- phosphoenolpyruvate is a substrate of ENO1ProteinRhea RHEA:10164Inferred only
- phosphoenolpyruvate is a substrate of ENO2ProteinRhea RHEA:10164Inferred only
- phosphoenolpyruvate is a substrate of ENO3ProteinRhea RHEA:10164Inferred only
- phosphoenolpyruvate is a substrate of ENO4ProteinRhea RHEA:10164Inferred only
- phosphoenolpyruvate is a substrate of NANSProteinRhea RHEA:49200Inferred only
- phosphoenolpyruvate is a substrate of NANSProteinRhea RHEA:80835Inferred only
- phosphoenolpyruvate is a substrate of PCK1ProteinRhea RHEA:10388Inferred only
- phosphoenolpyruvate is a substrate of PCK2ProteinRhea RHEA:10388Inferred only
- phosphoenolpyruvate is a substrate of PKLRProteinRhea RHEA:18157Inferred only
- phosphoenolpyruvate is a substrate of PKMProteinRhea RHEA:18157Inferred only
- phosphoenolpyruvate is transported by SLC25A1ProteinRhea RHEA:72487Inferred only
Reactions
40 reactions
(2R)-2-phosphoglyceratephosphoenolpyruvate+water
Catalysed by ENO4 or ENO1 or ENO2 or ENO3
Reaction pageReversibleBalanced
Rhea RHEA:10164CC BY 4.0Reference data
oxaloacetate+GTPphosphoenolpyruvate+GDP+carbon dioxide
Reaction pageReversibleBalanced
Rhea RHEA:10388CC BY 4.0Reference data
pyruvate+hydrogenphosphate+ATP(4-)phosphoenolpyruvate+AMP+diphosphate(3-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:10756CC BY 4.0Reference data
pyruvate+ATP(4-)+waterphosphoenolpyruvate+AMP+hydrogenphosphate+2hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:11364CC BY 4.0Reference data
CHEBI:57666+phosphoenolpyruvate+waterCHEBI:57537+hydrogenphosphate
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:13421CC BY 4.0Reference data
CHEBI:57693+phosphoenolpyruvate+waterCHEBI:85985+hydrogenphosphate
Reaction pageDirection not assertedBalanced
Rhea RHEA:14053CC BY 4.0Reference data
D-erythrose 4-phosphate+phosphoenolpyruvate+waterCHEBI:58394+hydrogenphosphate
Reaction pageDirection not assertedBalanced
Rhea RHEA:14717CC BY 4.0Reference data
phosphoenolpyruvate+hydronCHEBI:71402
Reaction pageDirection not assertedBalanced
Rhea RHEA:17013CC BY 4.0Reference data
pyruvate+ATP(4-)phosphoenolpyruvate+ADP(3-)+hydron
Reaction pageRight to leftBalanced
Rhea RHEA:18157CC BY 4.0Reference data
dihydroxyacetone+phosphoenolpyruvatedihydroxyacetone phosphate+pyruvate
Reaction pageDirection not assertedBalanced
Rhea RHEA:18381CC BY 4.0Reference data
oxaloacetate+ATP(4-)phosphoenolpyruvate+ADP(3-)+carbon dioxide
Reaction pageDirection not assertedBalanced
Rhea RHEA:18617CC BY 4.0Reference data
phosphoenolpyruvate+UDP-N-acetyl-alpha-D-glucosamineCHEBI:68483+hydrogenphosphate
Reaction pageDirection not assertedBalanced
Rhea RHEA:18681CC BY 4.0Reference data
Where it reaches
7 systems, 11 regions, 24 tissues, 24 transporter routes — routes, not measurements: transporters known to carry phosphoenolpyruvate are expressed there, and no source reports it arriving.
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Other names
3 names
Resolves to: phosphoenolpyruvate
- Also called
- phosphonatoenolpyruvate(3-)phosphonatoenolpyruvate(3−)
- Systematic name
- 2-(phosphonoatooxy)prop-2-enoate