Compound
dTMP
5-Thymidylic acid. A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety.
Structure
No depiction stored
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- Class
- Organic compound, anion
- Formula
- C10H13N2O8P
- Mass
- 320.194 g/mol
- Charge
- -2
- InChIKey
- GYOZYWVXFNDGLU-XLPZGREQSA-L
- SMILES
- Cc1cn([C@H]2C[C@H](O)[C@@H](COP(=O)([O-])[O-])O2)c(=O)nc1=O
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
11 entities
11 entities reached.
0 reported hops11 assembled from the scaffold
- NT5EProteinUNIPROT:P21589substrate ofInferred only63 paths21 endpoints
- TYMSProteinUNIPROT:P04818substrate ofInferred only24 paths24 endpoints
- NT5CProteinUNIPROT:Q8TCD5substrate ofInferred only24 paths8 endpoints
- DTYMKProteinUNIPROT:P23919substrate ofInferred only16 paths4 endpoints
- ENTPD1ProteinUNIPROT:P49961substrate ofInferred only13 paths13 endpoints
- NT5C2ProteinUNIPROT:P49902substrate ofInferred only12 paths12 endpoints
- ACP3ProteinUNIPROT:P15309substrate ofInferred only10 paths5 endpoints
- NT5C1AProteinUNIPROT:Q9BXI3substrate ofInferred only10 paths5 endpoints
- NT5C3AProteinUNIPROT:Q9H0P0substrate ofInferred only8 paths4 endpoints
- ENTPD3ProteinUNIPROT:O75355substrate ofInferred only5 paths5 endpoints
- NT5C3BProteinUNIPROT:Q969T7substrate ofInferred only3 paths3 endpoints
What the reference databases state
Statements
39 statements
39 statements · 2 reference databases · Subject: dTMP · Sources: Human-GEM, Rhea
- dTDP is converted to dTMPCompoundHuman-GEM MAR04637Inferred only
- dTMP is converted to dTDPCompoundHuman-GEM MAR04637Inferred only
- dTMP is converted to dTDPCompoundHuman-GEM MAR08274Inferred only
- dTMP is converted to dTDPCompoundHuman-GEM MAR02124Inferred only
- dTDP is converted to dTMPCompoundHuman-GEM MAR02124Inferred only
- thymidine is converted to dTMPCompoundHuman-GEM MAR04483Inferred only
- dTMP is converted to thymidineCompoundHuman-GEM MAR07725Inferred only
- dTMP is converted to thymidineCompoundHuman-GEM MAR04484Inferred only
- dTMP is converted to thymidineCompoundHuman-GEM MAR04056Inferred only
- thymidine is converted to dTMPCompoundHuman-GEM MAR04054Inferred only
- dTMP is a substrate of ACP3ProteinHuman-GEM MAR04056Inferred only
- dTMP is a substrate of ACP3ProteinHuman-GEM MAR04484Inferred only
Show the remaining 27
- dTMP is a substrate of DTYMKProteinHuman-GEM MAR04637Inferred only
- dTMP is a substrate of DTYMKProteinHuman-GEM MAR06613Inferred only
- dTMP is a substrate of DTYMKProteinHuman-GEM MAR08274Inferred only
- dTMP is a substrate of DTYMKProteinHuman-GEM MAR06612Inferred only
- dTMP is a substrate of ENTPD1ProteinHuman-GEM MAR02124Inferred only
- dTMP is a substrate of ENTPD3ProteinHuman-GEM MAR02124Inferred only
- dTMP is a substrate of ENTPD8ProteinHuman-GEM MAR02124Inferred only
- dTMP is a substrate of NT5CProteinHuman-GEM MAR04484Inferred only
- dTMP is a substrate of NT5CProteinHuman-GEM MAR04056Inferred only
- dTMP is a substrate of NT5CProteinHuman-GEM MAR07725Inferred only
- dTMP is a substrate of NT5C1AProteinHuman-GEM MAR07725Inferred only
- dTMP is a substrate of NT5C1AProteinHuman-GEM MAR04056Inferred only
- dTMP is a substrate of NT5C1BProteinHuman-GEM MAR04056Inferred only
- dTMP is a substrate of NT5C1BProteinHuman-GEM MAR07725Inferred only
- dTMP is a substrate of NT5C1BProteinHuman-GEM MAR04484Inferred only
- dTMP is a substrate of NT5C2ProteinHuman-GEM MAR04056Inferred only
- dTMP is a substrate of NT5C3AProteinHuman-GEM MAR04484Inferred only
- dTMP is a substrate of NT5C3AProteinHuman-GEM MAR04056Inferred only
- dTMP is a substrate of NT5C3BProteinHuman-GEM MAR04056Inferred only
- dTMP is a substrate of NT5EProteinHuman-GEM MAR04484Inferred only
- dTMP is a substrate of NT5EProteinHuman-GEM MAR04056Inferred only
- dTMP is a substrate of NT5EProteinHuman-GEM MAR07725Inferred only
- dTMP is a substrate of NT5MProteinHuman-GEM MAR04484Inferred only
- dTMP is a substrate of NT5MProteinHuman-GEM MAR07725Inferred only
- dTMP is a substrate of NT5MProteinHuman-GEM MAR04056Inferred only
- dTMP is a substrate of RBAKProteinHuman-GEM MAR04056Inferred only
- dTMP is a substrate of TYMSProteinRhea RHEA:12104Inferred only
Reactions
33 reactions
Reaction pageReversibleBalance undeterminableGO:0005615
Human-GEM MAR01923CC BY 4.0Reference data
dTDP+waterdTMP+proton+phosphate(3-)
Catalysed by ENTPD1 or ENTPD3 or ENTPD8
Reaction pageReversibleBalancedEC 3.6.1.5GO:0005615
Human-GEM MAR02124CC BY 4.0Reference data
Catalysed by TK1
Reaction pageLeft to rightBalancedEC 2.7.1.21GO:0005829
Human-GEM MAR04054CC BY 4.0Reference data
dTMP+waterphosphate(3-)+thymidine
Catalysed by ACP3 or NT5C2 or NT5C1A or NT5C3A or NT5C or NT5E or NT5C3B or RBAK or NT5C1B or NT5M
Reaction pageLeft to rightBalancedEC 3.1.3.5, 3.1.3.35GO:0005829
Human-GEM MAR04056CC BY 4.0Reference data
Catalysed by TK2
Reaction pageLeft to rightBalancedEC 2.7.1.21GO:0005759
Human-GEM MAR04483CC BY 4.0Reference data
dTMP+waterphosphate(3-)+thymidine
Catalysed by ACP3 or NT5C3A or NT5C or NT5E or NT5C1B or NT5M
Reaction pageLeft to rightBalancedEC 3.1.3.5, 3.1.3.35GO:0005759
Human-GEM MAR04484CC BY 4.0Reference data
Catalysed by DTYMK
Reaction pageReversibleBalancedEC 2.7.4.12, 2.7.4.9GO:0005829
Human-GEM MAR04637CC BY 4.0Reference data
(6R)-5,10-methylenetetrahydrofolic acid+dUMP7,8-dihydrofolate+dTMP
Catalysed by TYMS
Reaction pageLeft to rightBalancedEC 2.1.1.45GO:0005829
Human-GEM MAR04644CC BY 4.0Reference data
Reaction pageReversibleBalancedGO:0005829, GO:0005759
Human-GEM MAR05304CC BY 4.0Reference data
CHEBI:16174+dTDPCHEBI:16284+dTMP
Catalysed by DTYMK
Reaction pageReversibleBalancedEC 2.7.4.9GO:0005759
Human-GEM MAR06612CC BY 4.0Reference data
CHEBI:16174+dTDPCHEBI:16284+dTMP
Catalysed by DTYMK
Reaction pageReversibleBalancedEC 2.7.4.9GO:0005634
Human-GEM MAR06613CC BY 4.0Reference data
MAM01721n+water0.3MAM01639n+0.2dCMP+0.2dGMP+0.3dTMP+proton
Catalysed by RAD1 & RAD9A or TREX2 or TREX1
Reaction pageLeft to rightBalance undeterminableEC 3.1.11.2GO:0005634
Human-GEM MAR07163CC BY 4.0Reference data
Other names
8 names
Resolves to: dTMP
- Also called
- ribothymidine 5'-monophosphate anionthymidine 5'-monophosphatethymidine 5'-phosphatethymidine 5'-phosphate(2-)thymidine 5'-phosphate(2−)TMP dianion
- Systematic name
- 5-methyluridine 5'-phosphate5'-O-phosphonatothymidine