phosphoenolpyruvate

1. pyruvate + ATP = phosphoenolpyruvate + ADP + H(+)

Catalysed by PKM, PKLR

1. oxaloacetate + GTP = phosphoenolpyruvate + GDP + CO2

Catalysed by PCK1, PCK2

1. aldehydo-N-acetyl-D-mannosamine 6-phosphate + phosphoenolpyruvate + H2O = N-acetylneuraminate 9-phosphate + phosphate

Catalysed by NANS

1. phosphoenolpyruvate(in) + citrate(out) = phosphoenolpyruvate(out) + citrate(in)

Catalysed by SLC25A1inner side of the membrane, outer side of the membraneOne of 2 routes

1. (2R)-2-phosphoglycerate = phosphoenolpyruvate + H2O

Catalysed by ENO4, ENO1, ENO2, ENO3

1. aldehydo-D-mannose 6-phosphate + phosphoenolpyruvate + H2O = 3-deoxy-D-glycero-beta-D-galacto-non-2-ulopyranosonate 9-phosphate + phosphate

Catalysed by NANS

1. oxaloacetate + GTP = phosphoenolpyruvate + GDP + CO2
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)

Catalysed by PCK1, PCK2, CSmitochondrial matrixOne of 2 routes

1. pyruvate + ATP = phosphoenolpyruvate + ADP + H(+)
2. transport of 2-hydroxybutyrate and pyruvate (cytosol to extracellular)

Catalysed by PKM, PKLR, SLC16A4, SLC16A5 and 4 moreextracellular space, cytosol