cis-aconitate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

53 compounds within 3 steps: 2 in 1, 13 in 2, 38 in 3

One step

itaconateReach from here →
1. cis-aconitate + H(+) = itaconate + CO2
Catalysed by ACOD1
citric acidReach from here →
1. cis-aconitate(in) + citrate(out) = cis-aconitate(out) + citrate(in)
Catalysed by SLC25A1inner side of the membrane, outer side of the membraneOne of 2 routes

Two steps

D-threo-isocitrateReach from here →
1. cis-aconitate(in) + citrate(out) = cis-aconitate(out) + citrate(in)
2. citrate = D-threo-isocitrate
Catalysed by SLC25A1, ACO1, ACO2inner side of the membrane, outer side of the membraneOne of 3 routes
(S)-malateReach from here →
1. cis-aconitate(in) + citrate(out) = cis-aconitate(out) + citrate(in)
2. Citrate Transport, Mitochondrial
Catalysed by SLC25A1inner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosolOne of 5 routes
trans-aconitate

Three steps

CHEBI:1146900Reach from here →
Catalysed by ACOD1, SUCLG1, SUCLG2, SUCLA2mitochondrial matrixOne of 4 routes
pyruvateReach from here →
Catalysed by

Reach from here →

Catalysed by SLC25A1inner side of the membrane, outer side of the membraneOne of 2 routes

oxaloacetateReach from here →

Catalysed by SLC25A1, ACLYinner side of the membrane, outer side of the membrane, cytosolOne of 3 routes

oxalic acidReach from here →

Catalysed by SLC25A1inner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosolOne of 3 routes

maleateReach from here →

Catalysed by SLC25A1inner side of the membrane, outer side of the membraneOne of 2 routes

isocitric acidReach from here →

Catalysed by SLC25A1, ACO1inner side of the membrane, outer side of the membrane, cytosolOne of 3 routes

glutarateReach from here →

Catalysed by ACOD1, SUGCT

cis-aconitic acidReach from here →

Catalysed by SLC25A1, ACO2inner side of the membrane, outer side of the membrane, mitochondrial matrixOne of 3 routes

phosphoenolpyruvic acidReach from here →

Catalysed by SLC25A1inner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosolOne of 2 routes

itaconyl-CoAReach from here →

Catalysed by ACOD1, SUCLG1, SUCLG2, SUCLA2mitochondrial matrixOne of 4 routes

phosphoenolpyruvateReach from here →

Catalysed by SLC25A1inner side of the membrane, outer side of the membraneOne of 2 routes

beta-citrylglutamateReach from here →

Catalysed by SLC25A1, RIMKLBinner side of the membrane, outer side of the membrane

SLC25A1

, ME2

, ME3

inner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosol

One of 17 routes

malonateReach from here →

Catalysed by SLC25A1, SLC25A10inner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosolOne of 2 routes

sulfateReach from here →

Catalysed by SLC25A1, SLC25A10inner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosolOne of 7 routes

CHEBI:16284Reach from here →

Catalysed by SLC25A1, PKM, PKLRinner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosol

(R)-carnitineReach from here →

Catalysed by ACOD1, SUGCT, SLC22A8inner side of the membrane, outer side of the membraneOne of 2 routes

CHEBI:16497Reach from here →

Catalysed by SLC25A1, PKM, PKLRinner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosol

3-hydroxy-3-methylglutarateReach from here →

Catalysed by ACOD1, SUGCT

sulfiteReach from here →

Catalysed by SLC25A1, SLC25A10inner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosolOne of 2 routes

enol-oxaloacetateReach from here →

Catalysed by SLC25A1, SDHB, SDHAinner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosol

urateReach from here →

Catalysed by ACOD1, SUGCT, SLC22A8inner side of the membrane, outer side of the membraneOne of 2 routes

fumaric acidReach from here →

Catalysed by SLC25A1, FHinner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosolOne of 5 routes

dTTPReach from here →

Catalysed by SLC25A1, PKM, PKLRinner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosol

5alpha-androstane-3alpha,17beta-diol 3-O-(beta-D-glucuronate)Reach from here →

Catalysed by ACOD1, SUGCT, SLC22A24inner side of the membrane, outer side of the membraneOne of 2 routes

5-(3,3-dimethylguanidino)-2-oxopentanoateReach from here →

Catalysed by SLC25A1, ACLY, AGXT2inner side of the membrane, outer side of the membrane, cytosol

N-acetylneuraminate 9-phosphateReach from here →

Catalysed by SLC25A1, NANSinner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosolOne of 2 routes

a quinolReach from here →

Catalysed by SLC25A1, SDHB, SDHAinner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosol

chlorine(.)Reach from here →

Catalysed by SLC25A1, SLC26A6inner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosol, extracellular space

glycocholateReach from here →

Catalysed by ACOD1, SUGCT, SLC22A24inner side of the membrane, outer side of the membraneOne of 2 routes

L-aspartateReach from here →

Catalysed by SLC25A1, ACLY, GOT2inner side of the membrane, outer side of the membrane, cytosol, mitochondrial matrixOne of 5 routes

adipic acidReach from here →

Catalysed by ACOD1, SUGCT

4-hydroxy-2-oxoglutaric acidReach from here →

Catalysed by SLC25A1, ACLY, GOT2inner side of the membrane, outer side of the membrane, cytosol, mitochondrial matrix

thiosulfateReach from here →

Catalysed by SLC25A1, SLC25A10inner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosolOne of 2 routes

taurocholateReach from here →

Catalysed by ACOD1, SUGCT, SLC22A24, SLC22A8inner side of the membrane, outer side of the membraneOne of 2 routes

glyoxylateReach from here →

Catalysed by SLC25A1, CLYBLinner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosol

CHEBI:36882Reach from here →

Catalysed by ACOD1, SUCLG1, SUCLG2, SUCLA2 and 1 moremitochondrial matrix

succinyl-CoAReach from here →

Catalysed by ACOD1, SUCLG1, SUCLG2, SUCLA2 and 1 moremitochondrial matrix

(S)-malyl-CoAReach from here →

Catalysed by SLC25A1, SUCLG1, SUCLA2inner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosol

glutaryl-CoAReach from here →

Catalysed by ACOD1, SUCLG1, SUCLG2, SUCLA2 and 1 moremitochondrial matrixOne of 5 routes

prostaglandin F2alphaReach from here →

Catalysed by ACOD1, SUGCT, SLC22A8inner side of the membrane, outer side of the membraneOne of 2 routes

dehydroepiandrosterone 3-sulfateReach from here →

Catalysed by ACOD1, SUGCT, SLC22A24, SLC22A8inner side of the membrane, outer side of the membraneOne of 2 routes

(2R)-2-phosphoglycerateReach from here →

Catalysed by SLC25A1, ENO1, ENO2, ENO3inner side of the membrane, outer side of the membrane, mitochondrial matrix, cytosolOne of 2 routes

kynurenateReach from here →

Catalysed by ACOD1, SUGCT, SLC22A6inner side of the membrane, outer side of the membraneOne of 2 routes

(3S)-citramalyl-CoAReach from here →

Catalysed by ACOD1, SUCLG1, SUCLG2, SUCLA2 and 1 moremitochondrial matrix

estrone 3-sulfateReach from here →

Catalysed by ACOD1, SUGCT, SLC22A24, SLC22A8 and 1 moreinner side of the membrane, outer side of the membraneOne of 2 routes