Compound

(2R)-2-phosphoglycerate

An organophosphate oxoanion arising from deprotonation of the phosphate OH and carboxy groups of 2-phospho-D-glyceric acid; major species at pH 7.3.

Definition from ChEBI (CHEBI:58289), read 2026-09-23. CC BY 4.0.

CHEBI:58289ChEBI

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Structure

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A generated conformer of (2R)-2-phosphoglycerate — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, anion
Formula: C3H4O7P
Mass: 183.032 g/mol
Charge: -3
InChIKey: GXIURPTVHJPJLF-UWTATZPHSA-K
SMILES: O=C([O-])[C@@H](CO)OP(=O)([O-])[O-]
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

7 entities

7 entities reached.

0 reported hops7 assembled from the scaffold

What the reference databases state

Statements

28 statements

28 statements · 2 reference databases · Subject: (2R)-2-phosphoglycerate · Sources: Human-GEM, Rhea

Order

(2R)-2-phosphoglycerate is converted to (2R)-3-phosphoglycerateCompoundHuman-GEM MAR04365Inferred only
(2R)-3-phosphoglycerate is converted to (2R)-2-phosphoglycerateCompoundRhea RHEA:15901Inferred only
(2R)-3-phosphoglycerate is converted to (2R)-2-phosphoglycerateCompoundHuman-GEM MAR04365Inferred only
(2R)-2-phosphoglycerate is converted to (2R)-3-phosphoglycerateCompoundRhea RHEA:15901Inferred only
(R)-glycerate is converted to (2R)-2-phosphoglycerateCompoundRhea RHEA:27377Inferred only
(2R)-2-phosphoglycerate is converted to (R)-glycerateCompoundRhea RHEA:21156Inferred only
(2R)-2-phosphoglycerate is converted to (R)-glycerateCompoundRhea RHEA:27377Inferred only
(R)-glycerate is converted to (2R)-2-phosphoglycerateCompoundHuman-GEM MAR08781Inferred only
(R)-glycerate is converted to (2R)-2-phosphoglycerateCompoundRhea RHEA:21156Inferred only
phosphoenolpyruvate is converted to (2R)-2-phosphoglycerateCompoundRhea RHEA:10164Inferred only
(2R)-2-phosphoglycerate is converted to phosphoenolpyruvateCompoundRhea RHEA:10164Inferred only
(2R)-2-phosphoglycerate is converted to phosphoenolpyruvic acidCompoundHuman-GEM MAR04363Inferred only

Show the remaining 16

phosphoenolpyruvic acid is converted to (2R)-2-phosphoglycerateCompoundHuman-GEM MAR04363Inferred only
(2R)-2-phosphoglycerate is a substrate of BPGMProteinHuman-GEM MAR04365Inferred only
(2R)-2-phosphoglycerate is a substrate of BPGMProteinRhea RHEA:15901Inferred only
(2R)-2-phosphoglycerate is a substrate of ENO1ProteinHuman-GEM MAR04363Inferred only
(2R)-2-phosphoglycerate is a substrate of ENO1ProteinRhea RHEA:10164Inferred only
(2R)-2-phosphoglycerate is a substrate of ENO2ProteinHuman-GEM MAR04363Inferred only
(2R)-2-phosphoglycerate is a substrate of ENO2ProteinRhea RHEA:10164Inferred only
(2R)-2-phosphoglycerate is a substrate of ENO3ProteinRhea RHEA:10164Inferred only
(2R)-2-phosphoglycerate is a substrate of ENO3ProteinHuman-GEM MAR04363Inferred only
(2R)-2-phosphoglycerate is a substrate of ENO4ProteinRhea RHEA:10164Inferred only
(2R)-2-phosphoglycerate is a substrate of PGAM1ProteinRhea RHEA:15901Inferred only
(2R)-2-phosphoglycerate is a substrate of PGAM1ProteinHuman-GEM MAR04365Inferred only
(2R)-2-phosphoglycerate is a substrate of PGAM2ProteinHuman-GEM MAR04365Inferred only
(2R)-2-phosphoglycerate is a substrate of PGAM2ProteinRhea RHEA:15901Inferred only
(2R)-2-phosphoglycerate is a substrate of PGAM4ProteinHuman-GEM MAR04365Inferred only
(2R)-2-phosphoglycerate is a substrate of PGAM4ProteinRhea RHEA:15901Inferred only

Reactions

11 reactions

(2R)-2-phosphoglyceratewater+phosphoenolpyruvic acid
Catalysed by ENO1 or ENO3 or ENO2
Reaction pageReversibleBalancedEC 4.2.1.11cytosol
Human-GEM MAR04363CC BY 4.0Reference data
(2R)-2-phosphoglycerate(2R)-3-phosphoglycerate
Catalysed by PGAM2 or PGAM1 or BPGM or PGAM4
Reaction pageReversibleBalancedEC 5.4.2.11cytosol
Human-GEM MAR04365CC BY 4.0Reference data
ATP+(R)-glycerate(2R)-2-phosphoglycerate+ADP+proton
Reaction pageLeft to rightBalancedcytosol
Human-GEM MAR08781CC BY 4.0Reference data
(2R)-2-phosphoglycerate(2R)-2-phosphoglycerate
Reaction pageReversibleBalancedextracellular space, cytosol
Human-GEM MAR09820CC BY 4.0Reference data
(2R)-2-phosphoglycerate
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR09842CC BY 4.0Reference data
(2R)-2-phosphoglyceratephosphoenolpyruvate+water
Catalysed by ENO4 or ENO1 or ENO2 or ENO3
Reaction pageReversibleBalanced
Rhea RHEA:10164CC BY 4.0Reference data
(2R)-2-phosphoglycerate(2R)-3-phosphoglycerate
Catalysed by BPGM or PGAM2 or PGAM1 or PGAM4
Reaction pageReversibleBalanced
Rhea RHEA:15901CC BY 4.0Reference data
(2R)-2-phosphoglycerate+water(R)-glycerate+hydrogenphosphate
Reaction pageDirection not assertedBalanced
Rhea RHEA:21156CC BY 4.0Reference data
(R)-glycerate+ATP(4-)(2R)-2-phosphoglycerate+ADP(3-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:27377CC BY 4.0Reference data
CHEBI:58248+water(2R)-2-phosphoglycerate+hydrogenphosphate
Catalysed by MINPP1
Reaction pageLeft to rightBalanced
Rhea RHEA:27381CC BY 4.0Reference data
(2R)-2-phosphoglycerate+ATP(4-)CHEBI:58248+ADP(3-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:42408CC BY 4.0Reference data

Other names

4 names

Resolves to: (2R)-2-phosphoglycerate

Also called: 2-phospho-D-glycerate2-phosphonato-D-glycerate2-phosphonato-D-glycerate trianion
Systematic name: (2R)-3-hydroxy-2-(phosphonatooxy)propanoate