Compound
adipic acid
An α,ω-dicarboxylic acid that is the 1,4-dicarboxy derivative of butane.
Definition from ChEBI (CHEBI:30832), read 2026-09-23. CC BY 4.0.
Structure
Loading the model…
- Class
- Organic compound
- Formula
- C6H10O4
- Mass
- 146.142 g/mol
- Charge
- 0
- InChIKey
- WNLRTRBMVRJNCN-UHFFFAOYSA-N
- SMILES
- O=C(O)CCCCC(=O)O
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What the reference databases state
Statements
3 statements
3 statements · 1 reference database · Subject: adipic acid · Sources: Rhea
- hexanedioyl-CoA is converted to adipic acidCompoundRhea RHEA:40583Inferred only
- adipic acid is a substrate of SUGCTProteinRhea RHEA:81711Inferred only
- adipic acid is transported by SLC25A21ProteinRhea RHEA:71743Inferred only
Reactions
9 reactions
ATP+CHEBI:1146900+adipic acidAMP+diphosphate(3-)+hexanedioyl-CoA
Reaction pageLeft to rightBalancedcytosol
Human-GEM MAR04441CC BY 4.0Reference data
Reaction pageReversibleBalancedperoxisome, cytosol
Human-GEM MAR04443CC BY 4.0Reference data
water+hexanedioyl-CoACHEBI:1146900+proton+adipic acid
Catalysed by ACOT8
Reaction pageLeft to rightBalancedEC 3.1.2.-peroxisome
Human-GEM MAR04447CC BY 4.0Reference data
Reaction pageReversibleBalancedEC 3.1.1.4cytosol, extracellular space
Human-GEM MAR10001CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR10200CC BY 4.0Reference data
CHEBI:18322+NADP(3-)+wateradipic acid+NADPH(4-)+2hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:13397CC BY 4.0Reference data
hexanedioyl-CoA+wateradipic acid+coenzyme A(4-)+hydron
Catalysed by ACOT8
Reaction pageLeft to rightBalanced
Rhea RHEA:40583CC BY 4.0Reference data
adipic acid+2-oxoglutarate(2-)adipic acid+2-oxoglutarate(2-)
Transported by SLC25A21
Reaction pageDirection not assertedBalanced
Rhea RHEA:71743CC BY 4.0Reference data
adipic acid+glutaryl-CoAhexanedioyl-CoA+glutarate
Catalysed by SUGCT
Reaction pageReversibleBalanced
Rhea RHEA:81711CC BY 4.0Reference data
Papers screened
5 papers
- Compound
- adipic acid
- Screened
- 5
- Admitted
- 0
- Discarded
- 3
- Not read
- 2
Discarded: another reason, stated per paper2 papers
- NCT04200365design×1 — allocation NA -- not randomised2026-09-29
- NCT04339101design×1 — allocation NA -- not randomised2026-09-29
Discarded: the wrong intervention1 paper
- NCT02151643intervention×1 — no declared intervention names adipic acid2026-09-29
Not read yet2 papers
- PMID:161179792026-09-29
- PMID:250346182026-09-29
Other names
9 names
Resolves to: adipic acid
- Also called
- 1,4-butanedicarboxylic acid1,6-hexanedioic acidadipinic acidE 355E-355E355FA 6:1;O2INS No. 355
- Systematic name
- hexanedioic acid