(2R)-2-phosphoglycerate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

81 compounds within 3 steps: 3 in 1, 12 in 2, 66 in 3

One step

phosphoenolpyruvic acidReach from here →
1. 2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming)
Catalysed by ENO1, ENO2, ENO3cytosol
(2R)-3-phosphoglycerateReach from here →
1. D-phosphoglycerate 2,3-phosphomutase
Catalysed by BPGM, PGAM2, PGAM1, PGAM4cytosolOne of 2 routes
phosphoenolpyruvateReach from here →
1. (2R)-2-phosphoglycerate = phosphoenolpyruvate + H2O
Catalysed by ENO4, ENO1, ENO2, ENO3

Two steps

pyruvateReach from here →
1. 2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming)
2. GTP:pyruvate 2-O-phosphotransferase
Catalysed by ENO1, ENO2, ENO3, PKM and 1 morecytosolOne of 8 routes
CHEBI:16284Reach from here →
1. 2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming)
2. dATP:pyruvate 2-O-phosphotransferase
Catalysed by ENO1, ENO2, ENO3, PKM and 1 morecytosol

Three steps

oxaloacetateReach from here →

Catalysed by ENO4, ENO1, ENO2, ENO3 and 2 more

CHEBI:16497Reach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 1 morecytosol

(R)-glycerateReach from here →

Catalysed by BPGM, PGAM2, PGAM1, PGAM4 and 1 morecytosol

dTTPReach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 1 morecytosol

N-acetylneuraminate 9-phosphateReach from here →

Catalysed by ENO1, ENO2, ENO3, NANScytosolOne of 2 routes

citric acidReach from here →

Catalysed by ENO1, ENO2, ENO3, SLC25A1cytosol, mitochondrial matrixOne of 4 routes

isocitric acidReach from here →

Catalysed by ENO1, ENO2, ENO3, SLC25A1cytosol, mitochondrial matrixOne of 2 routes

cis-aconitic acidReach from here →

Catalysed by ENO1, ENO2, ENO3, SLC25A1cytosol, mitochondrial matrixOne of 2 routes

(2R)-3-phospho-glyceroyl phosphateReach from here →

Catalysed by BPGM, PGAM2, PGAM1, PGAM4 and 3 morecytosolOne of 2 routes

3-deoxy-D-glycero-beta-D-galacto-non-2-ulopyranosonate 9-phosphateReach from here →

Catalysed by ENO4, ENO1, ENO2, ENO3 and 1 more

Catalysed by ENO1, ENO2, ENO3, PKM and 7 more

cytosol, extracellular space

One of 2 routes

acetoacetateReach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 1 morecytosol, mitochondrial matrixOne of 4 routes

acetylpyruvateReach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 2 morecytosol

all-trans-retinoic acidReach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 7 morecytosol, extracellular spaceOne of 2 routes

D-threo-isocitrateReach from here →

Catalysed by ENO1, ENO2, ENO3, SLC25A1 and 2 morecytosol, mitochondrial matrixOne of 3 routes

(S)-malateReach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 2 morecytosolOne of 18 routes

trans-aconitateReach from here →

Catalysed by ENO1, ENO2, ENO3, SLC25A1cytosol, mitochondrial matrix, inner side of the membrane, outer side of the membraneOne of 2 routes

alpha-D-glucosamine 6-phosphateReach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 4 morecytosol

keto-D-fructose 6-phosphateReach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 5 morecytosol

CHEBI:16174Reach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 6 morecytosolOne of 20 routes

2-methyl-3-oxopropanoic acidReach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 2 morecytosol, mitochondrial matrix

cis-aconitateReach from here →

Catalysed by ENO1, ENO2, ENO3, SLC25A1cytosol, mitochondrial matrix, inner side of the membrane, outer side of the membraneOne of 2 routes

(S)-lactateReach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 6 morecytosol

2-oxobutanoateReach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 2 morecytosol

2-oxoglutaramateReach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 2 morecytosolOne of 2 routes

3-fumarylpyruvateReach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 2 morecytosol

oxalic acidReach from here →

Catalysed by ENO1, ENO2, ENO3, SLC25A1cytosol, mitochondrial matrixOne of 9 routes

(R)-3-hydroxybutyric acidReach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 7 morecytosol, extracellular spaceOne of 2 routes

3-hydroxypyruvateReach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 2 morecytosolOne of 3 routes

itaconateReach from here →

Catalysed by ENO1, ENO2, ENO3, SLC25A1 and 1 morecytosol, mitochondrial matrix

aceneuramateReach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 2 morecytosol

5'-deoxyadenosineReach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 3 morecytosol

thymidineReach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 2 morecytosol

triphosphateReach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 2 morecytosol

dTDPReach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 1 morecytosolOne of 12 routes

5-(3,3-dimethylguanidino)-2-oxopentanoateReach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 2 morecytosolOne of 2 routes

5-(3,3'-dimethylguanidino)-2-oxopentanoateReach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 2 morecytosol

5-(3-methylguanidino)-2-oxopentanoateReach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 2 morecytosol

dUMPReach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 1 morecytosolOne of 2 routes

CHEBI:28862Reach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 1 morecytosol, mitochondrial matrixOne of 13 routes

CHEBI:29052Reach from here →

Catalysed by BPGM, PGAM2, PGAM1, PGAM4 and 5 morecytosol

L-aspartateReach from here →

Catalysed by ENO4, ENO1, ENO2, ENO3 and 3 moremitochondrial matrixOne of 5 routes

acetateReach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 6 morecytosol, extracellular spaceOne of 2 routes

formic acidReach from here →

Catalysed by ENO1, ENO2, ENO3, PKM and 6 morecytosol, extracellular spaceOne of 2 routes