itaconate

1. itaconate + glutaryl-CoA = itaconyl-CoA + glutarate

Catalysed by SUGCT

1. Itaconate:CoA ligase (GDP-forming)

Catalysed by SUCLG1, SUCLG2, SUCLA2mitochondrial matrixOne of 4 routes

1. Itaconate:CoA ligase (GDP-forming)
2. Itaconate:CoA ligase (GDP-forming)

Catalysed by SUCLG1, SUCLG2, SUCLA2mitochondrial matrixOne of 2 routes

1. itaconate + glutaryl-CoA = itaconyl-CoA + glutarate
2. glutarate(in) + (R)-carnitine(out) = glutarate(out) + (R)-carnitine(in)

Catalysed by SUGCT, SLC22A8inner side of the membrane, outer side of the membraneOne of 2 routes

1. Itaconate:CoA ligase (GDP-forming)
2. Itaconate:CoA ligase (GDP-forming)
3. Carnitine O-Palmitoyltransferase

Catalysed by SUCLG1, SUCLG2, SUCLA2, CPT1A and 2 moremitochondrial matrix, cytosolOne of 244 routes

1. itaconate + glutaryl-CoA = itaconyl-CoA + glutarate
2. prostaglandin E2(out) + glutarate(in) = prostaglandin E2(in) + glutarate(out)
3. scavenger receptor class F (prostaglandin A2)