Loading the page.
Proteins/UNIPROT:Q8N4F4
Renal transmembrane organic anion/dicarboxylate exchanger that participates in the reabsorption of conjugated steroids including estradiol-17beta-D-glucuronide (or 17beta-estradiol 17-O-(beta-D-glucuronate)), androstanediol glucuronide (or 5alpha-androstane-3alpha,17beta-diol 3-O-(beta-D-glucuronate)), and estrone 3-sulfate, as well as bile acids taurocholate and glycocholate, driven by an outward gradient of dicarboxylates such as glutarate or succinate..
[Isoform 2]: Similar uptake function as Isoform 1..
[Isoform 3]: Lack of transporter activity..
Function from UniProtKB (Q8N4F4), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
15 statements
15 statements · 2 reference databases · Subject: SLC22A24 · Sources: Hetionet, Rhea
7 reactions
estrone 3-sulfate+glutarateestrone 3-sulfate+glutarate
Transported by SLC22A24 or SLC22A8 or SLC22A11
Reaction pageDirection not assertedBalanced
Rhea RHEA:72151CC BY 4.0Reference data
17beta-estradiol 17-O-(beta-D-glucuronate)+glutarate17beta-estradiol 17-O-(beta-D-glucuronate)+glutarate
Transported by SLC22A24
2 names
Resolves to: SLC22A24
Rhea RHEA:72155CC BY 4.0Reference data
taurocholate+glutaratetaurocholate+glutarate
Transported by SLC22A24 or SLC22A8
Reaction pageDirection not assertedBalanced
Rhea RHEA:72159CC BY 4.0Reference data
5alpha-androstane-3alpha,17beta-diol 3-O-(beta-D-glucuronate)+glutarate5alpha-androstane-3alpha,17beta-diol 3-O-(beta-D-glucuronate)+glutarate
Transported by SLC22A24
Reaction pageDirection not assertedBalanced
Rhea RHEA:72175CC BY 4.0Reference data
glycocholate+glutarateglycocholate+glutarate
Transported by SLC22A24
Reaction pageDirection not assertedBalanced
Rhea RHEA:72351CC BY 4.0Reference data
dehydroepiandrosterone 3-sulfate+glutaratedehydroepiandrosterone 3-sulfate+glutarate
Transported by SLC22A24 or SLC22A8
Reaction pageDirection not assertedBalanced
Rhea RHEA:72355CC BY 4.0Reference data
glutarate+succinate(2-)glutarate+succinate(2-)
Transported by SLC22A24
Reaction pageDirection not assertedBalanced
Rhea RHEA:72359CC BY 4.0Reference data