fumaric acid

1. a quinone + succinate = fumarate + a quinol

Catalysed by SDHB

1. (S)-malate hydro-lyase (fumarate-forming)

Catalysed by FHcytosolOne of 5 routes

1. transport of fumarate and sulfate (cytosol to mitochondria)

Catalysed by SLC25A10mitochondrial matrix, cytosolOne of 2 routes

1. succinate:quinone oxidoreductase

Catalysed by SDHD, SDHB, SDHA, SDHCmitochondrial matrix

1. 3-fumarylpyruvate + H2O = fumarate + pyruvate + H(+)

Catalysed by FAHD1

1. transport of fumarate and sulfite (cytosol to mitochondria)

Catalysed by SLC25A10mitochondrial matrix, cytosolOne of 2 routes

1. 4-fumarylacetoacetate + H2O = acetoacetate + fumarate + H(+)

Catalysed by FAH

1. transport of fumarate and thiosulfate (cytosol to mitochondria)

Catalysed by SLC25A10mitochondrial matrix, cytosolOne of 2 routes

1. 2-(Nomega-L-arginino)succinate arginine-lyase (fumarate-forming)

Catalysed by ASLcytosolOne of 2 routes

1. N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming)

Catalysed by ADSL, TNRC6BcytosolOne of 2 routes

1. 1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole AMP-lyase

Catalysed by ADSLcytosolOne of 2 routes

1. transport of fumarate and sulfate (cytosol to mitochondria)
2. Steryl-Sulfatase

Catalysed by SLC25A10, STSmitochondrial matrix, cytosol, Golgi apparatusOne of 2 routes

1. transport of fumarate and sulfate (cytosol to mitochondria)
2. steroid sulfatase (androsterone sulfate)

Catalysed by SLC25A10, STSmitochondrial matrix, cytosolOne of 3 routes