glutaryl-CoA

1. Production of Glutaryl Carnitine

Catalysed by CPT1A, CPT1C, CPT1Bcytosol

1. glutaryl-CoA + H2O = glutarate + CoA + H(+)

Catalysed by ACOT8, ACOT4One of 5 routes

1. 3-hydroxy-3-methylglutarate + glutaryl-CoA = (3S)-3-hydroxy-3-methylglutaryl-CoA + glutarate

Catalysed by SUGCT

1. glutarate + succinyl-CoA = glutaryl-CoA + succinate

Catalysed by SUGCT

1. glutaryl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase (decarboxylating)

Catalysed by GCDHmitochondrial matrixOne of 2 routes

1. glutaryl-CoA + O2 = (2E)-glutaconyl-CoA + H2O2

Catalysed by ACOX1

1. itaconate + glutaryl-CoA = itaconyl-CoA + glutarate

Catalysed by SUGCT

1. hexanedioate + glutaryl-CoA = hexanedioyl-CoA + glutarate

Catalysed by SUGCT

1. Production of Glutaryl Carnitine
2. Carnitine O-Palmitoyltransferase

Catalysed by CPT1A, CPT1C, CPT1BcytosolOne of 244 routes

1. 3-hydroxy-3-methylglutarate + glutaryl-CoA = (3S)-3-hydroxy-3-methylglutaryl-CoA + glutarate
2. (3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA

Catalysed by SUGCT, HMGCL, HMGCLL1