itaconyl-CoA

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

601 compounds within 3 steps: 6 in 1, 116 in 2, 479 in 3

One step

CHEBI:1146900Reach from here →
1. Itaconate:CoA ligase (GDP-forming)
Catalysed by SUCLG1, SUCLG2, SUCLA2mitochondrial matrixOne of 2 routes
itaconateReach from here →
1. Itaconate:CoA ligase (GDP-forming)
Catalysed by SUCLG1, SUCLG2, SUCLA2mitochondrial matrixOne of 4 routes
CHEBI:36882Reach from here →
1. (3S)-citramalyl-CoA hydro-lyase (itaconyl-CoA-forming)
Catalysed by AUHmitochondrial matrix
succinyl-CoAReach from here →
1. itaconate + succinyl-CoA = itaconyl-CoA + succinate
Catalysed by SUGCT
glutaryl-CoAReach from here →
1. itaconate + glutaryl-CoA = itaconyl-CoA + glutarate
Catalysed by SUGCT
(3S)-citramalyl-CoAReach from here →
1. (3S)-citramalyl-CoA = itaconyl-CoA + H2O
Catalysed by AUH

Two steps

(S)-carnitineReach from here →
1. Itaconate:CoA ligase (GDP-forming)
2. Carnitine O-Palmitoyltransferase
Catalysed by SUCLG1, SUCLG2, SUCLA2, CPT1A and 2 moremitochondrial matrix, cytosolOne of 244 routes
(7Z)-octadecenoyl-CoAReach from here →
1. Itaconate:CoA ligase (GDP-forming)
2. carnitine O-palmitoyltransferase ((7Z)-octadecenoyl-CoA)
Catalysed by SUCLG1, SUCLG2, SUCLA2, CPT1A and 2 more

mitochondrial matrix, cytosol

One of 3 routes

CHEBI:15345Reach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, AACSmitochondrial matrix, cytosolOne of 2 routes

cholineReach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, CHATmitochondrial matrix, nucleus

pyruvateReach from here →

Catalysed by AUH, CLYBLmitochondrial matrixOne of 2 routes

CHEBI:15380Reach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, ALAS1 and 1 moremitochondrial matrixOne of 8 routes

CHEBI:15477Reach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, GLYAT and 2 moremitochondrial matrixOne of 2 routes

2-methylcrotonoyl-CoAReach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, CPT1A and 1 moremitochondrial matrix, cytosolOne of 2 routes

isobutyryl-CoAReach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, HADHA and 2 moremitochondrial matrixOne of 3 routes

3-methylbut-2-enoyl-CoAReach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, GLYATmitochondrial matrix

isovaleryl-CoAReach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, GLYAT and 2 moremitochondrial matrixOne of 3 routes

arachidonoyl-CoAReach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, SLC27A2 and 7 moremitochondrial matrix, cytosolOne of 11 routes

CHEBI:15519Reach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, ACAA1 and 2 moremitochondrial matrix, peroxisomeOne of 2 routes

palmitoyl-CoAReach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, SLC27A2 and 7 moremitochondrial matrix, cytosolOne of 11 routes

oleoyl-CoAReach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, CPT1A and 2 moremitochondrial matrix, cytosolOne of 11 routes

phenylacetyl-CoAReach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2mitochondrial matrix, cytosolOne of 3 routes

propionyl-CoAReach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, ACSS3 and 2 moremitochondrial matrix, cytosolOne of 43 routes

CHEBI:15650Reach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, ZDHHC11B and 31 moremitochondrial matrix, cytosolOne of 2 routes

CHEBI:15727Reach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, NAA10mitochondrial matrix, cytosol

CHEBI:15746Reach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, SAT1 and 1 moremitochondrial matrix, cytosolOne of 2 routes

11-cis-retinolReach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, DGAT1 and 4 moremitochondrial matrix, cytosol

oxaloacetateReach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, ACLYmitochondrial matrix, cytosol

succinyl-4'-phosphopantetheineReach from here →

Catalysed by SUGCT, NUDT19, NUDT7, NUDT8

anilineReach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, NAT2 and 1 moremitochondrial matrix, cytosol

CHEBI:17312Reach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2mitochondrial matrix, cytosolOne of 2 routes

L-cysteineReach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, NAGSmitochondrial matrix

(7Z,10Z,13Z)-hexadecatrienoyl-CoAReach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, HADHA and 2 moremitochondrial matrix

CHEBI:17927Reach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2mitochondrial matrix, cytosol

(5Z)-dodecenoyl-CoAReach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, HADHA and 2 moremitochondrial matrixOne of 2 routes

(11Z)-docosenoyl-CoA(4-)Reach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, SLC27A2 and 7 moremitochondrial matrix, cytosolOne of 5 routes

(7Z)-tetradecenoyl-CoAReach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, SLC27A2 and 7 moremitochondrial matrix, cytosolOne of 8 routes

(4Z,7Z,10Z,13Z)-hexadecatetraenoyl-CoAReach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, HADHA and 2 moremitochondrial matrixOne of 3 routes

(7Z,10Z)-hexadecadienoyl-CoAReach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, HADHA and 2 moremitochondrial matrix

(4Z,7Z)-decadienoyl-CoAReach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, ECHS1 and 2 moremitochondrial matrixOne of 2 routes

(5Z)-octenoyl-CoAReach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, ECHS1 and 2 moremitochondrial matrixOne of 2 routes

CHEBI:27540Reach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, ACSM4 and 5 moremitochondrial matrix, cytosolOne of 6 routes

elaidic acidReach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, SLC27A2 and 7 moremitochondrial matrix, cytosolOne of 5 routes

CHEBI:28701Reach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, ACAA1 and 2 moremitochondrial matrix, peroxisomeOne of 7 routes

glutarateReach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, SUGCTmitochondrial matrixOne of 6 routes

5-aminolevulinateReach from here →

Catalysed by SUGCT, ALAS1, ALAS2

(3S)-3-hydroxy-3-methylglutaryl-CoAReach from here →

Catalysed by SUGCTOne of 2 routes

taurineReach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, BAATmitochondrial matrix, cytosolOne of 2 routes

acetoacetyl-CoAReach from here →

Catalysed by SUGCT, OXCT1

glycineReach from here →

Catalysed by SUCLG1, SUCLG2, SUCLA2, GLYAT and 2 moremitochondrial matrixOne of 10 routes