docosanoyl-CoA

1. Docosanoyl-CoA hydrolase

Catalysed by BAAT, ACOT6cytosolOne of 10 routes

1. Docosanoyl-CoA hydrolase

Catalysed by BAAT, ACOT6cytosolOne of 4 routes

1. docosanoyl-CoA + 2 NADPH + 2 H(+) = docosan-1-ol + 2 NADP(+) + CoA

Catalysed by FAR2

1. Fatty Acid Beta Oxidation (C22->C20), Peroxisomal

Catalysed by ACAA1, HSD17B4, EHHADH, ACOX1peroxisome

1. acyl-CoA pool formation and breakdown

No catalyst recordedcytosol

1. docosanoyl-CoA + sphinganine = N-docosanoylsphinganine + CoA + H(+)

Catalysed by CERS3, CERS2, CERS4

1. very-long-chain 3-oxoacyl-CoA synthase (docosanoyl-CoA)

Catalysed by ELOVL7, ELOVL1, ELOVL4, ELOVL6 and 3 morecytosolOne of 3 routes

1. acyl-CoA oxidase (docosanoyl-CoA)

Catalysed by ACOX3, ACOX1peroxisomeOne of 4 routes

1. docosanoyl-CoA + glycine = N-docosanoylglycine + CoA + H(+)

Catalysed by BAAT

1. Docosanoyl-CoA hydrolase
2. Carnitine O-Palmitoyltransferase

Catalysed by BAAT, ACOT6, CPT1A, CPT1C and 1 morecytosolOne of 244 routes

1. acyl-CoA pool formation and breakdown
2. an acyl-CoA + H2O = an acyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)

Catalysed by NUDT19, FITM2, NUDT8cytosol