Compound

(5Z)-dodecenoyl-CoA

An acyl-CoA(4-) species arising from deprotonation of the phosphate and diphosphate OH groups of cis-dodec-5-enoyl-CoA; major species at pH 7.3.

Definition from ChEBI (CHEBI:230464), read 2026-09-23. CC BY 4.0.

CHEBI:230464ChEBI

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Structure

2D depiction

No three-dimensional record for this entry.

Class: Organic compound, anion
Formula: C33H52N7O17P3S
Mass: 943.8 g/mol
Charge: -4
InChIKey: RCVJZGBRLGUTKT-CGGPSVLLSA-J
SMILES: CCCCCC/C=CCCCC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)([O-])OP(=O)([O-])OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)([O-])[O-]
Look it up: ChEBI By InChIKey

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

8 entities

8 entities reached.

0 reported hops8 assembled from the scaffold

What the reference databases state

Statements

17 statements

17 statements · 2 reference databases · Subject: (5Z)-dodecenoyl-CoA · Sources: Human-GEM, Rhea

Order

(2E)-dodecenoyl-CoA is converted to (5Z)-dodecenoyl-CoACompoundHuman-GEM MAR03375Inferred only
(5Z)-dodecenoyl-CoA is converted to (2E)-dodecenoyl-CoACompoundHuman-GEM MAR03272Inferred only
(5Z)-dodecenoyl-CoA is converted to (2E)-dodecenoyl-CoACompoundHuman-GEM MAR03375Inferred only
(2E)-dodecenoyl-CoA is converted to (5Z)-dodecenoyl-CoACompoundHuman-GEM MAR03272Inferred only
CHEBI:1146900 is converted to (5Z)-dodecenoyl-CoACompoundHuman-GEM MAR03373Inferred only
CHEBI:1146900 is converted to (5Z)-dodecenoyl-CoACompoundHuman-GEM MAR03264Inferred only
(5Z)-dodecenoyl-CoA is a substrate of ACADLProteinHuman-GEM MAR03291Inferred only
(5Z)-dodecenoyl-CoA is a substrate of ACOX1ProteinHuman-GEM MAR03295Inferred only
(5Z)-dodecenoyl-CoA is a substrate of ACOX3ProteinHuman-GEM MAR03295Inferred only
(5Z)-dodecenoyl-CoA is a substrate of ECH1ProteinHuman-GEM MAR03272Inferred only
(5Z)-dodecenoyl-CoA is a substrate of ECI1ProteinHuman-GEM MAR03375Inferred only
(5Z)-dodecenoyl-CoA is a substrate of ECI1ProteinHuman-GEM MAR03272Inferred only

Show the remaining 5

(5Z)-dodecenoyl-CoA is a substrate of ECI2ProteinHuman-GEM MAR03272Inferred only
(5Z)-dodecenoyl-CoA is a substrate of ECI2ProteinHuman-GEM MAR03375Inferred only
(5Z)-dodecenoyl-CoA is a substrate of EHHADHProteinHuman-GEM MAR03375Inferred only
(5Z)-dodecenoyl-CoA is a substrate of HADHAProteinHuman-GEM MAR03375Inferred only
(5Z)-dodecenoyl-CoA is a substrate of HADHBProteinRhea RHEA:82943Inferred only

Reactions

8 reactions

MAM00886m+CHEBI:1146900(5Z)-dodecenoyl-CoA+CHEBI:15351
Catalysed by HADHA & ACAA2 & HADHB
Reaction pageLeft to rightBalancedEC 2.3.1.16, 1.1.1.211GO:0005759
Human-GEM MAR03264CC BY 4.0Reference data
(2E)-dodecenoyl-CoA(5Z)-dodecenoyl-CoA
Catalysed by ECH1 or ECI1 or ECI2
Reaction pageReversibleBalancedEC 5.3.3.8, 5.3.3.-GO:0005759
Human-GEM MAR03272CC BY 4.0Reference data
FADH2+MAM03333m(5Z)-dodecenoyl-CoA+FAD
Catalysed by ACADL
Reaction pageReversibleBalancedEC 1.3.8.7, 1.3.8.8, 1.3.8.9GO:0005759
Human-GEM MAR03291CC BY 4.0Reference data
FADH2+MAM03333x(5Z)-dodecenoyl-CoA+FAD
Catalysed by ACOX3 or ACOX1
Reaction pageReversibleBalancedEC 1.3.8.7, 1.3.8.8, 1.3.8.9GO:0005777
Human-GEM MAR03295CC BY 4.0Reference data
MAM00886x+CHEBI:1146900(5Z)-dodecenoyl-CoA+CHEBI:15351
Catalysed by ACAA1 & MYO5B
Reaction pageLeft to rightBalancedEC 2.3.1.16GO:0005777
Human-GEM MAR03373CC BY 4.0Reference data
(2E)-dodecenoyl-CoA(5Z)-dodecenoyl-CoA
Catalysed by ECI2 & HADHA & ECI1 & EHHADH
Reaction pageReversibleBalancedEC 5.3.3.8GO:0005777
Human-GEM MAR03375CC BY 4.0Reference data
3-oxo-(7Z)-tetradecenoyl-CoA+coenzyme A(4-)(5Z)-dodecenoyl-CoA+acetyl-CoA
Catalysed by HADHB
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:82943CC BY 4.0Reference data
(5Z)-dodecenoyl-CoA+oxidized [electron-transfer flavoprotein]+hydronCHEBI:232684+reduced [electron-transfer flavoprotein]
Catalysed by ACADL or ACADVL or ACAD9
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:82951CC BY 4.0Reference data

Other names

1 name

Resolves to: (5Z)-dodecenoyl-CoA

Also called: CE0695