Compound
3-oxotetracosanoyl-CoA
A 3-oxo-fatty acyl-CoA(4−) arising from deprotonation of the phosphate and diphosphate functions of 3-oxotetracosanoyl-CoA.
Definition from ChEBI (CHEBI:73977), read 2026-09-23. CC BY 4.0.
Structure
No three-dimensional record for this entry.
- Class
- Organic compound, anion
- Formula
- C45H76N7O18P3S
- Mass
- 1128.123 g/mol
- Charge
- -4
- InChIKey
- JJSJTIWFKNSCHC-JBKAVQFISA-J
- SMILES
- CCCCCCCCCCCCCCCCCCCCCC(=O)CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)([O-])OP(=O)([O-])OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)([O-])[O-]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
3 entities
3 entities reached.
What the reference databases state
Statements
6 statements
6 statements · 2 reference databases · Subject: 3-oxotetracosanoyl-CoA · Sources: Human-GEM, Rhea
- 3-oxotetracosanoyl-CoA is converted to docosanoyl-CoACompoundRhea RHEA:78567Inferred only
- docosanoyl-CoA is converted to 3-oxotetracosanoyl-CoACompoundRhea RHEA:36507Inferred only
- docosanoyl-CoA is converted to 3-oxotetracosanoyl-CoACompoundRhea RHEA:78567Inferred only
- 3-oxotetracosanoyl-CoA is a substrate of ACAA1ProteinHuman-GEM MAR03065Inferred only
- 3-oxotetracosanoyl-CoA is a substrate of HSD17B12ProteinHuman-GEM MAR02212Inferred only
- 3-oxotetracosanoyl-CoA is a substrate of MYO5BProteinHuman-GEM MAR03065Inferred only
Reactions
10 reactions
docosanoyl-CoA+proton+malonyl-CoA3-oxotetracosanoyl-CoA+carbon dioxide+CHEBI:1146900
Catalysed by ELOVL5 or ELOVL1 or ELOVL4 or ELOVL3 or ELOVL7 or ELOVL6 or ELOVL2
Reaction pageLeft to rightBalancedEC 2.3.1.199cytosol
Human-GEM MAR02211CC BY 4.0Reference data
3-oxotetracosanoyl-CoA+proton+NADPH(4-)MAM00800c+NADP(3-)
Catalysed by HSD17B12
Reaction pageLeft to rightBalancedEC 1.1.1.330cytosol
Human-GEM MAR02212CC BY 4.0Reference data
docosanoyl-CoA+proton+malonyl-CoA3-oxotetracosanoyl-CoA+carbon dioxide+CHEBI:1146900
Catalysed by HIRIP3
Reaction pageLeft to rightBalancednucleus
Human-GEM MAR02498CC BY 4.0Reference data
MAM00800x+NAD(+)3-oxotetracosanoyl-CoA+proton+NADH(2-)
Catalysed by ACAA1 & HSD17B4 & EHHADH
Reaction pageLeft to rightBalancedEC 1.1.1.35, 1.1.1.211peroxisome
Human-GEM MAR03064CC BY 4.0Reference data
3-oxotetracosanoyl-CoA+CHEBI:1146900CHEBI:15351+docosanoyl-CoA
Reaction pageLeft to rightBalancedEC 2.3.1.16peroxisome
Human-GEM MAR03065CC BY 4.0Reference data
docosanoyl-CoA+malonyl-CoA+hydron3-oxotetracosanoyl-CoA+carbon dioxide+coenzyme A(4-)
Reaction pageLeft to rightBalanced
Rhea RHEA:36507CC BY 4.0Reference data
3-oxotetracosanoyl-CoA+NADPH(4-)+hydronCHEBI:76377+NADP(3-)
Reaction pageDirection not assertedBalanced
Rhea RHEA:39195CC BY 4.0Reference data
CHEBI:76377+NAD(1-)3-oxotetracosanoyl-CoA+NADH(2-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:78563CC BY 4.0Reference data
docosanoyl-CoA+acetyl-CoA3-oxotetracosanoyl-CoA+coenzyme A(4-)
Reaction pageDirection not assertedBalanced
Rhea RHEA:78567CC BY 4.0Reference data
CHEBI:87563+NAD(1-)3-oxotetracosanoyl-CoA+NADH(2-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:78735CC BY 4.0Reference data
Other names
19 names
Resolves to: 3-oxotetracosanoyl-CoA
- Also called
- 3-keto-C24-CoA(4-)3-keto-C24-CoA(4−)3-ketolignoceroyl-CoA(4-)3-ketolignoceroyl-CoA(4−)3-ketolignoceroyl-coenzyme A(4-)3-ketolignoceroyl-coenzyme A(4−)3-ketotetracosanoyl-CoA(4-)3-ketotetracosanoyl-CoA(4−)3-ketotetracosanoyl-coenzyme A(4-)3-ketotetracosanoyl-coenzyme A(4−)3-oxo-C24-CoA(4-)3-oxo-C24-CoA(4−)3-oxolignoceroyl-CoA(4-)3-oxolignoceroyl-CoA(4−)3-oxolignoceroyl-coenzyme A(4-)3-oxolignoceroyl-coenzyme A(4−)3-oxotetracosanoyl-coenzyme A(4-)3-oxotetracosanoyl-coenzyme A(4−)
- Systematic name
- 3'-phosphonatoadenosine 5'-{3-[(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-{[3-({2-[(3-oxotetracosanoyl)sulfanyl]ethyl}amino)-3-oxopropyl]amino}butyl] diphosphate}