Compound

2-methylcrotonoyl-CoA

CHEBI:15478ChEBI

Open in the graph

What it touches on the way

Mechanistic reach

8 entities

8 entities reached.

0 reported hops8 assembled from the scaffold

What the reference databases state

Statements

12 statements

12 statements · 1 reference database · Subject: 2-methylcrotonoyl-CoA · Sources: Human-GEM

Order

CHEBI:15477 is converted to 2-methylcrotonoyl-CoACompoundHuman-GEM MAR03784Inferred only
2-methylcrotonoyl-CoA is converted to CHEBI:15477CompoundHuman-GEM MAR03784Inferred only
2-methylcrotonoyl-CoA is a substrate of ACAD8ProteinHuman-GEM MAR03784Inferred only
2-methylcrotonoyl-CoA is a substrate of ACADSProteinHuman-GEM MAR03784Inferred only
2-methylcrotonoyl-CoA is a substrate of ACADSBProteinHuman-GEM MAR03784Inferred only
2-methylcrotonoyl-CoA is a substrate of CPT1AProteinHuman-GEM MAR04711Inferred only
2-methylcrotonoyl-CoA is a substrate of CPT1BProteinHuman-GEM MAR04711Inferred only
2-methylcrotonoyl-CoA is a substrate of ECHS1ProteinHuman-GEM MAR03785Inferred only
2-methylcrotonoyl-CoA is a substrate of GLYATProteinHuman-GEM MAR11509Inferred only
2-methylcrotonoyl-CoA is a substrate of MCCC1ProteinHuman-GEM MAR06926Inferred only
2-methylcrotonoyl-CoA is a substrate of MCCC2ProteinHuman-GEM MAR06926Inferred only
2-methylcrotonoyl-CoA is transported by DBIProteinHuman-GEM MAR04438Inferred only

Reactions

10 reactions

CHEBI:15477+FADFADH2+2-methylcrotonoyl-CoA
Catalysed by ACAD8 or ACADS or ACADSB
Reaction pageReversibleBalancedEC 1.3.8.5, 1.3.8.1GO:0005759
Human-GEM MAR03784CC BY 4.0Reference data
water+2-methylcrotonoyl-CoAMAM00171m
Catalysed by ECHS1
Reaction pageLeft to rightBalancedEC 4.2.1.17GO:0005759
Human-GEM MAR03785CC BY 4.0Reference data
2-methylcrotonoyl-CoA2-methylcrotonoyl-CoA
Transported by DBI
Reaction pageReversibleBalancedGO:0005759, GO:0005829
Human-GEM MAR04438CC BY 4.0Reference data
(S)-carnitine+2-methylcrotonoyl-CoACHEBI:1146900+MAM03496c
Catalysed by CPT1A or CPT1B
Reaction pageReversibleBalancedEC 2.3.1.21GO:0005829
Human-GEM MAR04711CC BY 4.0Reference data
MAM00667m+ADP+proton+phosphate(3-)ATP+hydrogencarbonate+2-methylcrotonoyl-CoA
Catalysed by MCCC1 & MCCC2
Reaction pageReversibleBalancedEC 6.4.1.4GO:0005759
Human-GEM MAR06926CC BY 4.0Reference data
glycine+2-methylcrotonoyl-CoACHEBI:1146900+proton+MAM03997m
Catalysed by GLYAT
Reaction pageReversibleBalancedEC 2.3.1.13GO:0005759
Human-GEM MAR11509CC BY 4.0Reference data
CHEBI:58446+2-methylcrotonoyl-CoACHEBI:58460+coenzyme A(4-)
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:12360CC BY 4.0Reference data
CHEBI:573122-methylcrotonoyl-CoA+water
Catalysed by EHHADH
Reaction pageRight to leftBalance undeterminable
Rhea RHEA:31119CC BY 4.0Reference data
2-methylbutanoyl-CoA+oxidized [electron-transfer flavoprotein]+hydron2-methylcrotonoyl-CoA+reduced [electron-transfer flavoprotein]
Catalysed by ACADSB
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:43780CC BY 4.0Reference data
CHEBI:88166+oxidized [electron-transfer flavoprotein]+hydron2-methylcrotonoyl-CoA+reduced [electron-transfer flavoprotein]
Catalysed by ACADSB or ACAD8
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:48256CC BY 4.0Reference data

Other names

8 names

Resolves to: 2-methylcrotonoyl-CoA

Also called: (E)-2-Methylcrotonoyl-CoA2-Methylcrotanoyl-CoAMethylcrotonoyl-CoAMethylcrotonyl-CoATigloyl-CoATiglyl-CoAtrans-2-Methylbut-2-enoyl-CoA
Systematic name: 3'-phosphoadenosine 5'-{3-[(3R)-3-hydroxy-2,2-dimethyl-4-({3-[(2-{[(2E)-2-methylbut-2-enoyl]sulfanyl}ethyl)amino]-3-oxopropyl}amino)-4-oxobutyl] dihydrogen diphosphate}