L-cysteine

1. N-acetylglutamate synthase (N-acetyl-L-cysteine)

Catalysed by NAGSmitochondrial matrix

1. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O

Catalysed by MOCOS

1. L-cysteine hydrogen-sulfide-lyase (deaminating

Catalysed by CTHcytosolOne of 2 routes

1. transport of cysteine and leucine (cytosol to extracellular)

Catalysed by SLC7A9, SLC3A1extracellular space, cytosolOne of 3 routes

1. transport of cysteine and homoserine (cytosol to extracellular)

Catalysed by SLC7A5extracellular space, cytosolOne of 3 routes

1. transport of cysteine and histidine (cytosol to extracellular)

Catalysed by SLC7A6extracellular space, cytosolOne of 2 routes

1. thioredoxin-disulfide reductase (NADPH) (cystine)

Catalysed by TXNRD1, TXNRD3, TXNRD2cytosolOne of 4 routes

1. transport of citrulline and cysteine (cytosol to extracellular)

Catalysed by SLC7A6extracellular space, cytosolOne of 2 routes

1. transport of cysteine and valine (cytosol to extracellular)

Catalysed by SLC7A5extracellular space, cytosolOne of 3 routes

1. transport of arginine and cysteine (cytosol to extracellular)

Catalysed by SLC7A6extracellular space, cytosolOne of 5 routes

1. PROTEIN_BS

No catalyst recordedcytosol

1. cystine to cysteine conversion

No catalyst recordedcytosol

1. transport of cysteine and threonine (cytosol to extracellular)

Catalysed by SLC7A5extracellular space, cytosolOne of 4 routes

1. transport of cysteine and isoleucine (cytosol to extracellular)

Catalysed by SLC7A5extracellular space, cytosolOne of 4 routes

1. transport of cysteine and proline (cytosol to extracellular)

Catalysed by SLC7A5extracellular space, cytosolOne of 3 routes

1. transport of cysteine and tyrosine (cytosol to extracellular)

Catalysed by SLC7A5extracellular space, cytosolOne of 4 routes

1. transport of cysteine and lysine (cytosol to extracellular)

Catalysed by SLC7A6extracellular space, cytosolOne of 2 routes

1. transport of cysteine and glutamine (cytosol to extracellular)

Catalysed by SLC3A2, SLC7A5, SLC7A10extracellular space, cytosolOne of 4 routes

1. S-sulfanyl-L-cysteine + L-cysteine = S-disulfanyl-L-cysteine + L-alanine

Catalysed by CARS2

1. N-acetylglutamate synthase (N-acetyl-L-cysteine)

Catalysed by NAGSmitochondrial matrix

1. K(+)(in) + L-cysteine(out) + 3 Na(+)(out) + H(+)(out) = K(+)(out) + L-cysteine(in) + 3 Na(+)(in) + H(+)(in)

Catalysed by SLC1A1inner side of the membrane, outer side of the membraneOne of 2 routes

1. L-Cysteine:tRNA(Cys) ligase (AMP-forming)

Catalysed by CARS1cytosol

1. transport of chloride and cysteine (cytosol to extracellular)

Catalysed by SLC6A14extracellular space, cytosolOne of 2 routes

1. L-cysteine hydrogen-sulfide-lyase (deaminating

Catalysed by CTHcytosolOne of 2 routes

1. De novo synthesis of 2Fe2S

Catalysed by NDUFAB1, FDXR, FXN, FDX2 and 3 moremitochondrial matrix

1. transport of cysteine and ornithine (cytosol to extracellular)

Catalysed by SLC7A6extracellular space, cytosolOne of 2 routes

1. transport of cysteine and glycine (cytosol to extracellular)

Catalysed by SLC3A2, SLC7A5, SLC7A8extracellular space, cytosolOne of 4 routes

1. L-Cysteine:2-oxoglutarate aminotransferase

Catalysed by GOT2, GOT1cytosolOne of 3 routes

1. transport of cysteine and methionine (cytosol to extracellular)

Catalysed by SLC7A5extracellular space, cytosolOne of 6 routes

1. transport of cysteine and tryptophan (cytosol to extracellular)

Catalysed by SLC7A5extracellular space, cytosolOne of 4 routes

1. transport of alanine and cysteine (cytosol to extracellular)

Catalysed by SLC7A5extracellular space, cytosolOne of 14 routes

1. transport of asparagine and cysteine (cytosol to extracellular)

Catalysed by SLC7A5extracellular space, cytosolOne of 4 routes

1. transport of cysteine and phenylalanine (cytosol to extracellular)

Catalysed by SLC7A5extracellular space, cytosolOne of 6 routes

1. L-glutamate:L-cysteine gamma-ligase (ADP-forming)

Catalysed by GCLC, GCLMcytosolOne of 2 routes

1. 2 L-cysteine = S-sulfanyl-L-cysteine + L-alanine

Catalysed by CARS2

1. (R)-4'-phosphopantothenate:L-cysteine ligase

Catalysed by PPCScytosolOne of 4 routes

1. L-Cysteine:oxygen oxidoreductase

Catalysed by CDO1cytosolOne of 2 routes

1. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O

Catalysed by MOCOS

1. transport of cysteine and tryptophan (cytosol to extracellular)
2. beta-carboline hydrolysis

Catalysed by SLC7A5extracellular space, cytosol

1. N-acetylglutamate synthase (N-acetyl-L-cysteine)
2. Carnitine O-Palmitoyltransferase

Catalysed by NAGS, CPT1A, CPT1C, CPT1Bmitochondrial matrix, cytosolOne of 245 routes