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Proteins/UNIPROT:P11245
Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates. Participates in the detoxification of a plethora of hydrazine and arylamine drugs, and is able to bioactivate several known carcinogens..
Function from UniProtKB (P11245), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
19 statements
19 statements · 5 reference databases · Subject: NAT2 · Sources: Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
3 reactions
MAM01251c+CHEBI:1146900CHEBI:15351+aniline
Reaction pageReversibleBalancedEC 2.3.1.5cytosol
Human-GEM MAR09527CC BY 4.0Reference data
an arylamine+acetyl-CoAan N-acetylarylamine+coenzyme A(4-)
Reaction pageDirection not asserted
7 names
Resolves to: NAT2
Rhea RHEA:16613CC BY 4.0Reference data
an N-hydroxyarylamine+acetyl-CoAan N-acetoxyarylamine+coenzyme A(4-)
Catalysed by NAT2
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:20277CC BY 4.0Reference data