eicosanoyl-CoA

1. Eicosanoyl-CoA hydrolase

Catalysed by BAAT, ACOT6, ACOT1cytosolOne of 10 routes

1. eicosanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyeicosanoyl-CoA + succinate + CO2

Catalysed by PHYH

1. eicosanoyl-CoA + 2-(9Z-octadecenoyl)-glycerol = 1-eicosanoyl-2-(9Z-octadecenoyl)-glycerol + CoA

Catalysed by MOGAT2, MOGAT1

1. Eicosanoyl-CoA hydrolase

Catalysed by BAAT, ACOT6, ACOT1cytosolOne of 4 routes

1. Beta Oxidation of Long Chain Fatty Acid

Catalysed by ACADM, ACADSmitochondrial matrixOne of 2 routes

1. acyl-CoA pool formation and breakdown

No catalyst recordedcytosol

1. eicosanoyl-CoA + sphinganine = N-eicosanoylsphinganine + CoA + H(+)

Catalysed by CERS1, CERS2, CERS4

1. very-long-chain 3-oxoacyl-CoA synthase (eicosanoyl-CoA)

Catalysed by ELOVL7, ELOVL1, ELOVL4, ELOVL6 and 3 morecytosolOne of 3 routes

1. eicosanoyl-CoA + sphing-4-enine = N-eicosanoyl-sphing-4-enine + CoA + H(+)

Catalysed by TLCD3B, CERS2

1. acyl-CoA oxidase (eicosanoyl-CoA)

Catalysed by ACOX3, ACOX1peroxisomeOne of 4 routes

1. eicosanoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-eicosanoyl-sn-glycero-3-phosphate + CoA

Catalysed by ABHD5

1. eicosanoyl-CoA + 2 NADPH + 2 H(+) = eicosan-1-ol + 2 NADP(+) + CoA

Catalysed by FAR1, FAR2

1. eicosanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-eicosanoyl-sn-glycero-3-phosphocholine + CoA

Catalysed by LPCAT1

1. eicosanoyl-CoA + (R)-carnitine = O-eicosanoyl-(R)-carnitine + CoA

Catalysed by CPT2

1. eicosanoyl-CoA + glycine = N-eicosanoylglycinate + CoA + H(+)

Catalysed by BAAT

1. Eicosanoyl-CoA hydrolase
2. Carnitine O-Palmitoyltransferase

Catalysed by BAAT, ACOT6, ACOT1, CPT1A and 2 morecytosolOne of 244 routes

1. acyl-CoA pool formation and breakdown
2. an acyl-CoA + H2O = an acyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)

Catalysed by NUDT19, FITM2, NUDT8cytosol