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Proteins/UNIPROT:Q3I5F7
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Catalyzes the hydrolysis of phytanoyl-CoA and pristanoyl-CoA, two methyl-branched fatty acids derived from phytol, that enter the body via the diet..
Function from UniProtKB (Q3I5F7), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
32 statements
32 statements · 4 reference databases · Subject: ACOT6 · Sources: Hetionet, Human-GEM, Rhea, WikiPathways
47 reactions
water+nonadecanoyl-CoACHEBI:1146900+proton+MAM02613c
Catalysed by ACOT1 or BAAT or ACOT6
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00280CC BY 4.0Reference data
eicosanoyl-CoA+waterCHEBI:1146900+eicosanoate+proton
Catalysed by
2 names
Resolves to: ACOT6
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00284CC BY 4.0Reference data
(13Z)-eicosenoyl-CoA+waterMAM00017c+CHEBI:1146900+proton
Catalysed by ACOT1 or BAAT or ACOT6
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00290CC BY 4.0Reference data
(11Z)-eicosenoyl-CoA+water(11Z)-eicosenoate+CHEBI:1146900+proton
Catalysed by ACOT1 or BAAT or ACOT6
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00294CC BY 4.0Reference data
MAM01236c+waterMAM01235c+CHEBI:1146900+proton
Catalysed by ACOT1 or BAAT or ACOT6
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00298CC BY 4.0Reference data
MAM00123c+waterMAM01207c+CHEBI:1146900+proton
Catalysed by ACOT1 or BAAT or ACOT6
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00302CC BY 4.0Reference data
MAM00101c+waterCHEBI:1146900+proton+(5Z,8Z,11Z)-eicosatrienoate
Catalysed by ACOT1 or BAAT or ACOT6
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00306CC BY 4.0Reference data
water+MAM02052cCHEBI:1146900+proton+MAM02053c
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00310CC BY 4.0Reference data
docosanoyl-CoA+waterdocosanoate+CHEBI:1146900+proton
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00314CC BY 4.0Reference data
(13Z)-docosenoyl-CoA+waterMAM01583c+CHEBI:1146900+proton
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00320CC BY 4.0Reference data
water+tricosanoyl-CoACHEBI:1146900+proton+tricosanoate
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00328CC BY 4.0Reference data
(15Z)-tetracosenoyl-CoA+waterCHEBI:1146900+proton+(15Z)-tetracosenoate
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00338CC BY 4.0Reference data