Compound

CHEBI:15519

A steroidal acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of cholic acid.

Definition from ChEBI (CHEBI:15519), read 2026-09-23. CC BY 4.0.

CHEBI:15519ChEBI

Open in the graph

What it touches on the way

Mechanistic reach

6 entities

6 entities reached.

0 reported hops6 assembled from the scaffold

What the reference databases state

Statements

11 statements

11 statements · 1 reference database · Subject: CHEBI:15519 · Sources: Human-GEM

Order

CHEBI:15519 is a substrate of ACOT8ProteinHuman-GEM MAR01663Inferred only
CHEBI:15519 is a substrate of ACOT8ProteinHuman-GEM MAR01660Inferred only
CHEBI:15519 is a substrate of BAATProteinHuman-GEM MAR01670Inferred only
CHEBI:15519 is a substrate of BAATProteinHuman-GEM MAR01667Inferred only
CHEBI:15519 is a substrate of BAATProteinHuman-GEM MAR01668Inferred only
CHEBI:15519 is a substrate of BAATProteinHuman-GEM MAR00083Inferred only
CHEBI:15519 is transported by ABCD1ProteinHuman-GEM MAR01659Inferred only
CHEBI:15519 is transported by BCAP31ProteinHuman-GEM MAR01659Inferred only
CHEBI:15519 is transported by IDH3GProteinHuman-GEM MAR01659Inferred only
CHEBI:15519 is transported by PDZD4ProteinHuman-GEM MAR01659Inferred only
CHEBI:15519 is transported by SRPK3ProteinHuman-GEM MAR01659Inferred only

Reactions

10 reactions

CHEBI:15519+glycineCHEBI:1146900+glycocholate
Catalysed by BAAT
Reaction pageLeft to rightBalancedEC 2.3.1.65GO:0005777
Human-GEM MAR00083CC BY 4.0Reference data
3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA+CHEBI:1146900CHEBI:15519+propionyl-CoA
Catalysed by ACAA1 or SCP2 or MYO5B
Reaction pageLeft to rightBalancedEC 2.3.1.176, 2.3.1.16GO:0005777
Human-GEM MAR01652CC BY 4.0Reference data
ATP+CHEBI:15519+waterADP+CHEBI:15519+proton+phosphate(3-)
Transported by IDH3G or PDZD4 or ABCD1 or SRPK3 or BCAP31
Reaction pageLeft to rightBalancedGO:0005829, GO:0005777
Human-GEM MAR01659CC BY 4.0Reference data
CHEBI:15519+watercholate+CHEBI:1146900+proton
Catalysed by ACOT8
Reaction pageLeft to rightBalancedEC 3.1.2.27GO:0005829
Human-GEM MAR01660CC BY 4.0Reference data
CHEBI:15519+watercholate+CHEBI:1146900+proton
Catalysed by ACOT8
Reaction pageLeft to rightBalancedEC 3.1.2.27GO:0005777
Human-GEM MAR01663CC BY 4.0Reference data
CHEBI:15519+taurineCHEBI:1146900+taurocholate
Catalysed by BAAT
Reaction pageLeft to rightBalancedEC 2.3.1.65GO:0005777
Human-GEM MAR01667CC BY 4.0Reference data
CHEBI:15519+taurineCHEBI:1146900+taurocholate
Catalysed by BAAT
Reaction pageLeft to rightBalancedEC 2.3.1.65GO:0005829
Human-GEM MAR01668CC BY 4.0Reference data
CHEBI:15519+glycineCHEBI:1146900+glycocholate
Catalysed by BAAT
Reaction pageLeft to rightBalancedEC 2.3.1.65GO:0005829
Human-GEM MAR01670CC BY 4.0Reference data
ATP+cholate+CHEBI:1146900AMP+CHEBI:15519+diphosphate(3-)
Catalysed by SLC27A5 or SLC27A2
Reaction pageLeft to rightBalancedEC 6.2.1.7GO:0005783
Human-GEM MAR01848CC BY 4.0Reference data
CHEBI:15519CHEBI:15519
Reaction pageReversibleBalancedGO:0005783, GO:0005829
Human-GEM MAR02275CC BY 4.0Reference data

Other names

14 names

Resolves to: CHEBI:15519

Also called: 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholan-24-one-CoA3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oyl-CoA3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oyl-coenzyme A3alpha,7alpha,12alpha-Trihydroxy-5beta-cholanoyl-CoA3α,7α,12α-trihydroxy-5β-cholan-24-oyl-CoA3α,7α,12α-trihydroxy-5β-cholan-24-oyl-coenzyme ACholoyl-CoAcholoyl-coenzyme Acholyl-CoAcholyl-coenzyme AS-(3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oyl)-CoAS-(3α,7α,12α-trihydroxy-5β-cholan-24-oyl)-CoA
Systematic name: 3'-phosphoadenosine 5'-{3-[(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-{[3-oxo-3-({2-[(3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oyl)sulfanyl]ethyl}amino)propyl]amino}butyl] dihydrogen diphosphate}3'-phosphoadenosine 5'-{3-[(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-{[3-oxo-3-({2-[(3α,7α,12α-trihydroxy-5β-cholan-24-oyl)sulfanyl]ethyl}amino)propyl]amino}butyl] dihydrogen diphosphate}