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Proteins/UNIPROT:Q6NUI2
Transfers an acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate producing a lysophosphatidic acid (LPA), an essential step for the triacylglycerol (TAG) and glycerophospholipids. In vitro also transfers an acyl-group from acyl-ACP to the LPA producing a phosphatidic acid (PA). Prefers arachidonoyl-CoA as the acyl donor. Required for primary processing step during piRNA biosynthesis. Molecular mechanisms by which it promotes piRNA biosynthesis are unclear and do not involve its acyltransferase activity..
Function from UniProtKB (Q6NUI2), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
134 statements
134 statements · 5 reference databases · Subject: GPAT2 · Sources: Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
65 reactions
dodecanoyl-CoA+CHEBI:159781-dodecanoyl-sn-glycerol 3-phosphate+CHEBI:1146900
Catalysed by GPAM or GPAT3 or GPAT4 or GPAT2
Reaction pageLeft to rightBalancedEC 2.3.1.15cytosol
Human-GEM MAR00486CC BY 4.0Reference data
CHEBI:15978+MAM03050cMAM00502c+CHEBI:1146900
Catalysed by GPAM
3 names
Resolves to: GPAT2
Reaction pageLeft to rightBalancedEC 2.3.1.15cytosol
Human-GEM MAR00487CC BY 4.0Reference data
tetradecanoyl-CoA+CHEBI:159781-tetradecanoyl-sn-glycerol 3-phosphate+CHEBI:1146900
Catalysed by GPAM or GPAT3 or GPAT4 or GPAT2
Reaction pageLeft to rightBalancedEC 2.3.1.15cytosol
Human-GEM MAR00488CC BY 4.0Reference data
MAM00129c+CHEBI:15978MAM00471c+CHEBI:1146900
Catalysed by GPAM or GPAT3 or GPAT4 or GPAT2
Reaction pageLeft to rightBalancedEC 2.3.1.15cytosol
Human-GEM MAR00489CC BY 4.0Reference data
(7Z)-tetradecenoyl-CoA+CHEBI:15978MAM00463c+CHEBI:1146900
Catalysed by GPAM or GPAT3 or GPAT4 or GPAT2
Reaction pageLeft to rightBalancedEC 2.3.1.15cytosol
Human-GEM MAR00490CC BY 4.0Reference data
(5Z)-tetradecenoyl-CoA+CHEBI:15978MAM00454c+CHEBI:1146900
Catalysed by GPAM or GPAT3 or GPAT4 or GPAT2
Reaction pageLeft to rightBalancedEC 2.3.1.15cytosol
Human-GEM MAR00491CC BY 4.0Reference data
MAM02689c+CHEBI:15978MAM00498c+CHEBI:1146900
Catalysed by GPAM or GPAT3 or GPAT4 or GPAT2
Reaction pageLeft to rightBalancedEC 2.3.1.15cytosol
Human-GEM MAR00492CC BY 4.0Reference data
palmitoyl-CoA+CHEBI:159781-hexadecanoyl-sn-glycero-3-phosphate+CHEBI:1146900
Catalysed by GPAM or GPAT3 or GPAT4 or GPAT2
Reaction pageLeft to rightBalancedEC 2.3.1.15cytosol
Human-GEM MAR00493CC BY 4.0Reference data
(9Z)-hexadecenoyl-CoA+CHEBI:15978MAM00497c+CHEBI:1146900
Catalysed by GPAM or GPAT3 or GPAT4 or GPAT2
Reaction pageLeft to rightBalancedEC 2.3.1.15cytosol
Human-GEM MAR00494CC BY 4.0Reference data
(7Z)-hexadecenoyl-CoA+CHEBI:15978MAM00461c+CHEBI:1146900
Catalysed by GPAM or GPAT3 or GPAT4 or GPAT2
Reaction pageLeft to rightBalancedEC 2.3.1.15cytosol
Human-GEM MAR00495CC BY 4.0Reference data
heptadecanoyl-CoA+CHEBI:15978MAM00481c+CHEBI:1146900
Catalysed by GPAM or GPAT3 or GPAT4 or GPAT2
Reaction pageLeft to rightBalancedEC 2.3.1.15cytosol
Human-GEM MAR00496CC BY 4.0Reference data
MAM00004c+CHEBI:15978MAM00438c+CHEBI:1146900
Catalysed by GPAM or GPAT3 or GPAT4 or GPAT2
Reaction pageLeft to rightBalancedEC 2.3.1.15cytosol
Human-GEM MAR00497CC BY 4.0Reference data