Compound

1,2-diacyl-sn-glycero-3-phosphocholine(1+)

A complex mixture of phospholipids; glycolipids; and triglycerides; with substantial amounts of phosphatidylcholines; phosphatidylethanolamines; and phosphatidylinositols, which are sometimes loosely termed as 1,2-diacyl-3-phosphocholines. Lecithin is a component of the cell membrane and commercially extracted from soybeans and EGG yolk. The emulsifying and surfactant properties are useful in food additives and for forming organogels (gels).

Definition from MeSH (D054709), National Library of Medicine, read 2026-09-23. NLM revises MeSH; this copy may not reflect its current record.

CHEBI:16110ChEBI

Open in the graph

What it touches on the way

Mechanistic reach

40 entities

40 entities reached.

0 reported hops40 assembled from the scaffold

Show the remaining 28

What the reference databases state

Statements

97 statements

97 statements · 1 reference database · Subject: 1,2-diacyl-sn-glycero-3-phosphocholine(1+) · Sources: Human-GEM

Order

phosphatidylethanolamine is converted to 1,2-diacyl-sn-glycero-3-phosphocholine(1+)CompoundHuman-GEM MAR01603Inferred only
phosphatidylethanolamine is converted to 1,2-diacyl-sn-glycero-3-phosphocholine(1+)CompoundHuman-GEM MAR01606Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of AWAT1ProteinHuman-GEM MAR06639Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of AWAT2ProteinHuman-GEM MAR06635Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of AWAT2ProteinHuman-GEM MAR06639Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of BSCL2ProteinHuman-GEM MAR00031Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of DGAT1ProteinHuman-GEM MAR06635Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of DGAT1ProteinHuman-GEM MAR06639Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of DGAT2ProteinHuman-GEM MAR06639Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of DGAT2ProteinHuman-GEM MAR06635Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of FITM1ProteinHuman-GEM MAR00031Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of FITM2ProteinHuman-GEM MAR00031Inferred only

Show the remaining 85

1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of LCATProteinHuman-GEM MAR00634Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of LCATProteinHuman-GEM MAR01475Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of LRATProteinHuman-GEM MAR06639Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of LRATProteinHuman-GEM MAR01501Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of LRATProteinHuman-GEM MAR06635Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G10ProteinHuman-GEM MAR00463Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G10ProteinHuman-GEM MAR00630Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G10ProteinHuman-GEM MAR05254Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G12AProteinHuman-GEM MAR00463Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G12AProteinHuman-GEM MAR00630Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G12AProteinHuman-GEM MAR05254Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G1BProteinHuman-GEM MAR05254Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G1BProteinHuman-GEM MAR00463Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G1BProteinHuman-GEM MAR00630Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G2AProteinHuman-GEM MAR05254Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G2AProteinHuman-GEM MAR00463Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G2AProteinHuman-GEM MAR00630Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G2DProteinHuman-GEM MAR05254Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G2DProteinHuman-GEM MAR00630Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G2DProteinHuman-GEM MAR00463Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G2EProteinHuman-GEM MAR00463Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G2EProteinHuman-GEM MAR00630Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G2EProteinHuman-GEM MAR05254Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G2FProteinHuman-GEM MAR00463Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G2FProteinHuman-GEM MAR00630Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G2FProteinHuman-GEM MAR05254Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G3ProteinHuman-GEM MAR05254Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G3ProteinHuman-GEM MAR00630Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G3ProteinHuman-GEM MAR00463Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G4AProteinHuman-GEM MAR00463Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G4AProteinHuman-GEM MAR00630Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G4AProteinHuman-GEM MAR05254Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G4BProteinHuman-GEM MAR05254Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G4BProteinHuman-GEM MAR00463Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G4BProteinHuman-GEM MAR00630Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G4CProteinHuman-GEM MAR00630Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G4CProteinHuman-GEM MAR05254Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G4CProteinHuman-GEM MAR00463Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G4DProteinHuman-GEM MAR05254Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G4DProteinHuman-GEM MAR00630Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G4DProteinHuman-GEM MAR00463Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G4EProteinHuman-GEM MAR05254Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G4EProteinHuman-GEM MAR00630Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G4EProteinHuman-GEM MAR00463Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G4FProteinHuman-GEM MAR00463Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G4FProteinHuman-GEM MAR05254Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G4FProteinHuman-GEM MAR00630Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G5ProteinHuman-GEM MAR00630Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G5ProteinHuman-GEM MAR00463Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G5ProteinHuman-GEM MAR05254Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G6ProteinHuman-GEM MAR05254Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G6ProteinHuman-GEM MAR00463Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLA2G6ProteinHuman-GEM MAR00630Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLAAT3ProteinHuman-GEM MAR00463Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLAAT3ProteinHuman-GEM MAR00630Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLAAT3ProteinHuman-GEM MAR05254Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLB1ProteinHuman-GEM MAR05254Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLB1ProteinHuman-GEM MAR00630Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLB1ProteinHuman-GEM MAR00463Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLD1ProteinHuman-GEM MAR08523Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLD1ProteinHuman-GEM MAR01586Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLD1ProteinHuman-GEM MAR00629Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLD1ProteinHuman-GEM MAR08525Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLD2ProteinHuman-GEM MAR00629Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLD2ProteinHuman-GEM MAR08525Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLD2ProteinHuman-GEM MAR08523Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLD6ProteinHuman-GEM MAR00629Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLIN1ProteinHuman-GEM MAR00031Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLIN2ProteinHuman-GEM MAR00031Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLIN3ProteinHuman-GEM MAR00031Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PLIN4ProteinHuman-GEM MAR00031Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of PTDSS1ProteinHuman-GEM MAR00623Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of RBP1ProteinHuman-GEM MAR06639Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of RBP1ProteinHuman-GEM MAR06635Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of RBP2ProteinHuman-GEM MAR06635Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of RBP2ProteinHuman-GEM MAR06639Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of SGMS1ProteinHuman-GEM MAR00736Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of SGMS1ProteinHuman-GEM MAR00735Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of SGMS2ProteinHuman-GEM MAR00735Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of SGMS2ProteinHuman-GEM MAR12079Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is a substrate of SGMS2ProteinHuman-GEM MAR00736Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is transported by ABCA1ProteinHuman-GEM MAR00476Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is transported by ABCB4ProteinHuman-GEM MAR00476Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is transported by ATP10AProteinHuman-GEM MAR01583Inferred only
1,2-diacyl-sn-glycero-3-phosphocholine(1+) is transported by PCTPProteinHuman-GEM MAR00461Inferred only

Reactions

48 reactions

0.19a 1,2-diacyl-sn-glycerol+0.0014MAM00511c+0.0024a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine+0.00061-O-acyl-sn-glycero-3-phosphocholine(1+)+0.005CHEBI:1307929+0.34a cholesterol ester+0.00081-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine+0.00921,2-diacyl-sn-glycero-3-phosphocholine(1+)+0.0034phosphatidylethanolamine+0.00161-phosphatidyl-1D-myo-inositol+0.0002phosphatidyl-L-serine+0.0004a sphingomyelin+0.44a triacylglycerol+0.005fatty acidMAM02392c
Catalysed by PLIN3 or FITM1 or PLIN2 or PLIN1 or PLIN4 or BSCL2 or FITM2
Reaction pageLeft to rightBalance undeterminablecytosol
Human-GEM MAR00031CC BY 4.0Reference data
1,2-diacyl-sn-glycero-3-phosphocholine(1+)1,2-diacyl-sn-glycero-3-phosphocholine(1+)
Transported by PCTP
Reaction pageReversibleBalance undeterminablecytosol, endoplasmic reticulum
Human-GEM MAR00461CC BY 4.0Reference data
water+1,2-diacyl-sn-glycero-3-phosphocholine(1+)1-O-acyl-sn-glycero-3-phosphocholine(1+)+proton+fatty acid
Catalysed by PLA2G10 or PLA2G3 or PLA2G4C or PLA2G4A or PLA2G2D or PLA2G12A or PLA2G5 or PLA2G2F or PLA2G4D or PLB1 or PLA2G4F or PLA2G1B and 6 more alternatives
Reaction pageLeft to rightBalance undeterminableEC 3.1.1.4endoplasmic reticulum
Human-GEM MAR00463CC BY 4.0Reference data
ATP+water+1,2-diacyl-sn-glycero-3-phosphocholine(1+)ADP+proton+1,2-diacyl-sn-glycero-3-phosphocholine(1+)+phosphate(3-)
Transported by ABCB4 or ABCA1
Reaction pageLeft to rightBalance undeterminablecytosol, extracellular space
Human-GEM MAR00476CC BY 4.0Reference data
2MAM01395e+1,2-diacyl-sn-glycero-3-phosphocholine(1+)+phosphatidylethanolamineMAM02740e
Reaction pageLeft to rightBalance undeterminableextracellular space
Human-GEM MAR00477CC BY 4.0Reference data
1,2-diacyl-sn-glycero-3-phosphocholine(1+)+L-seryl residuecholine+phosphatidyl-L-serine
Catalysed by PTDSS1
Reaction pageLeft to rightBalance undeterminableEC 2.7.8.29cytosol
Human-GEM MAR00623CC BY 4.0Reference data
a 1,2-diacyl-sn-glycerol+CHEBI:16436cytidine 5'-monophosphate+proton+1,2-diacyl-sn-glycero-3-phosphocholine(1+)
Catalysed by CHPT1 or CEPT1
Reaction pageLeft to rightBalance undeterminableEC 2.7.8.2cytosol
Human-GEM MAR00625CC BY 4.0Reference data
water+1,2-diacyl-sn-glycero-3-phosphocholine(1+)choline+proton+phosphatidic acid
Catalysed by PLD1 or PLD2 or PLD6
Reaction pageLeft to rightBalance undeterminableEC 3.1.4.4cytosol
Human-GEM MAR00629CC BY 4.0Reference data
water+1,2-diacyl-sn-glycero-3-phosphocholine(1+)1-O-acyl-sn-glycero-3-phosphocholine(1+)+proton+fatty acid
Catalysed by PLA2G10 or PLA2G3 or PLA2G4C or PLA2G4A or PLA2G2D or PLA2G12A or PLA2G5 or PLA2G2F or PLA2G4D or PLB1 or PLA2G4F or PLA2G1B and 6 more alternatives
Reaction pageLeft to rightBalance undeterminableEC 3.1.1.4cytosol
Human-GEM MAR00630CC BY 4.0Reference data
1-O-acyl-sn-glycero-3-phosphocholine(1+)+an acyl-CoACHEBI:1146900+1,2-diacyl-sn-glycero-3-phosphocholine(1+)
Catalysed by LPCAT2 or LPCAT3 or LPCAT1 or LPCAT4
Reaction pageLeft to rightBalance undeterminableEC 2.3.1.23cytosol
Human-GEM MAR00632CC BY 4.0Reference data
CHEBI:1307929+1,2-diacyl-sn-glycero-3-phosphocholine(1+)1-O-acyl-sn-glycero-3-phosphocholine(1+)+a cholesterol ester
Catalysed by LCAT
Reaction pageLeft to rightBalance undeterminableEC 2.3.1.43cytosol
Human-GEM MAR00634CC BY 4.0Reference data
1,2-diacyl-sn-glycero-3-phosphocholine(1+)
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR00655CC BY 4.0Reference data

Show the remaining 36

Where it reaches

2 systems, 2 regions, 4 tissues, 6 transporter routes — routes, not measurements: transporters known to carry 1,2-diacyl-sn-glycero-3-phosphocholine(1+) are expressed there, and no source reports it arriving.

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Digestive

Reproductive

Other names

11 names

Resolves to: 1,2-diacyl-sn-glycero-3-phosphocholine(1+)

Also called: (3-sn-phosphatidyl)choline1,2-Diacyl-sn-glycero-3-phosphocholine1,2-diacyl-sn-glycero-3-phosphocholinesCholine phosphatideL-alpha-phosphatidylcholineL-α-phosphatidylcholineLecithinlecithinsPCPhosphatidyl-N-trimethylethanolaminePhosphatidylcholine