Compound

(2E)-docosenoyl-CoA

An acyl-CoA(4−) arising from deprotonation of the phosphate and diphosphate functions of trans-2-docosenoyl-CoA.

Definition from ChEBI (CHEBI:74692), read 2026-09-23. CC BY 4.0.

CHEBI:74692ChEBI

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Structure

2D depiction

No three-dimensional record for this entry.

Class: Organic compound, anion
Formula: C43H72N7O17P3S
Mass: 1084.07 g/mol
Charge: -4
InChIKey: KRTIFNFQCJTGMV-DYAVHEMFSA-J
SMILES: CCCCCCCCCCCCCCCCCCC/C=C/C(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)([O-])OP(=O)([O-])OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)([O-])[O-]
Look it up: ChEBI By InChIKey

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

5 entities

5 entities reached.

0 reported hops5 assembled from the scaffold

What the reference databases state

Statements

11 statements

11 statements · 2 reference databases · Subject: (2E)-docosenoyl-CoA · Sources: Human-GEM, Rhea

Order

(2E)-docosenoyl-CoA is converted to docosanoyl-CoACompoundRhea RHEA:39191Inferred only
(2E)-docosenoyl-CoA is converted to docosanoyl-CoACompoundHuman-GEM MAR02210Inferred only
docosanoyl-CoA is converted to (2E)-docosenoyl-CoACompoundHuman-GEM MAR03107Inferred only
docosanoyl-CoA is converted to (2E)-docosenoyl-CoACompoundRhea RHEA:39191Inferred only
docosanoyl-CoA is converted to (2E)-docosenoyl-CoACompoundRhea RHEA:78571Inferred only
docosanoyl-CoA is converted to (2E)-docosenoyl-CoACompoundHuman-GEM MAR03066Inferred only
(2E)-docosenoyl-CoA is a substrate of EHHADHProteinHuman-GEM MAR03067Inferred only
(2E)-docosenoyl-CoA is a substrate of HADHAProteinHuman-GEM MAR03108Inferred only
(2E)-docosenoyl-CoA is a substrate of HSD17B4ProteinHuman-GEM MAR03067Inferred only
(2E)-docosenoyl-CoA is a substrate of TECRProteinHuman-GEM MAR02210Inferred only
(2E)-docosenoyl-CoA is a substrate of TECRLProteinHuman-GEM MAR02210Inferred only

Reactions

11 reactions

MAM00776c(2E)-docosenoyl-CoA+water
Catalysed by HACD3 or HIGD2A or HACD1 or HACD4 or HACD2
Reaction pageLeft to rightBalancedEC 4.2.1.134cytosol
Human-GEM MAR02209CC BY 4.0Reference data
(2E)-docosenoyl-CoA+proton+NADPH(4-)docosanoyl-CoA+NADP(3-)
Catalysed by TECR or TECRL
Reaction pageLeft to rightBalancedEC 1.3.1.93cytosol
Human-GEM MAR02210CC BY 4.0Reference data
docosanoyl-CoA+FAD(2E)-docosenoyl-CoA+FADH2
Catalysed by ACOX3 or ACOX1
Reaction pageLeft to rightBalancedEC 1.3.3.6peroxisome
Human-GEM MAR03066CC BY 4.0Reference data
(2E)-docosenoyl-CoA+waterMAM00776x
Catalysed by EHHADH or HSD17B4
Reaction pageLeft to rightBalancedEC 4.2.1.17peroxisome
Human-GEM MAR03067CC BY 4.0Reference data
docosanoyl-CoA+FAD(2E)-docosenoyl-CoA+FADH2
Catalysed by ACADVL or ACADL or ACAD9 or ACAD11
Reaction pageLeft to rightBalancedEC 1.3.8.7, 1.3.8.8, 1.3.8.9, 1.3.99.-mitochondrial matrix
Human-GEM MAR03107CC BY 4.0Reference data
(2E)-docosenoyl-CoA+waterMAM00776m
Catalysed by HADHA
Reaction pageLeft to rightBalancedEC 4.2.1.17mitochondrial matrix
Human-GEM MAR03108CC BY 4.0Reference data
CHEBI:76375(2E)-docosenoyl-CoA+water
Catalysed by HACD1 or HACD2
Reaction pageLeft to rightBalanced
Rhea RHEA:39187CC BY 4.0Reference data
(2E)-docosenoyl-CoA+NADPH(4-)+hydrondocosanoyl-CoA+NADP(3-)
Reaction pageDirection not assertedBalanced
Rhea RHEA:39191CC BY 4.0Reference data
docosanoyl-CoA+oxidized [electron-transfer flavoprotein]+hydron(2E)-docosenoyl-CoA+reduced [electron-transfer flavoprotein]
Catalysed by ACADL or ACADVL or ACAD11
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:47228CC BY 4.0Reference data
docosanoyl-CoA+dioxygen(2E)-docosenoyl-CoA+hydrogen peroxide
Catalysed by ACOX1
Reaction pageLeft to rightBalanced
Rhea RHEA:78571CC BY 4.0Reference data
CHEBI:87564(2E)-docosenoyl-CoA+water
Reaction pageDirection not assertedBalanced
Rhea RHEA:78575CC BY 4.0Reference data

Other names

7 names

Resolves to: (2E)-docosenoyl-CoA

Also called: (E)-2-docosenoyl-CoA(4-)(E)-2-docosenoyl-CoA(4−)(E)-2-docosenoyl-coenzyme A(4-)(E)-2-docosenoyl-coenzyme A(4−)trans-2-docosenoyl-coenzyme A(4-)trans-2-docosenoyl-coenzyme A(4−)
Systematic name: 3'-phosphonatoadenosine 5'-{3-[(3R)-4-({3-[(2-{[(2E)-docos-2-enoyl]sulfanyl}ethyl)amino]-3-oxopropyl}amino)-3-hydroxy-2,2-dimethyl-4-oxobutyl] diphosphate}