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Proteins/UNIPROT:P21673
Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine = spermidine >> spermine > N(1)-acetylspermine. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Also involved in the regulation of polyamine transport out of cells. Also acts on 1,3-diaminopropane and 1,5-diaminopentane..
Function from UniProtKB (P21673), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
392 statements
392 statements · 7 reference databases · Subject: SAT1 · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, WikiPathways · Rows fetched: 300
8 reactions
CHEBI:1146900+proton+CHEBI:17312CHEBI:15351+CHEBI:15746
Reaction pageReversibleBalancedEC 2.3.1.57cytosol
Human-GEM MAR06929CC BY 4.0Reference data
CHEBI:1146900+proton+CHEBI:17312CHEBI:15351+CHEBI:15746
Catalysed by
6 names
Resolves to: SAT1
Reaction pageReversibleBalancedEC 2.3.1.57peroxisome
Human-GEM MAR06930CC BY 4.0Reference data
CHEBI:1146900+proton+CHEBI:17927CHEBI:15351+spermidine
Reaction pageReversibleBalancedEC 2.3.1.57cytosol
Human-GEM MAR06938CC BY 4.0Reference data
CHEBI:1146900+proton+CHEBI:17927CHEBI:15351+spermidine
Reaction pageReversibleBalancedEC 2.3.1.57peroxisome
Human-GEM MAR06939CC BY 4.0Reference data
CHEBI:15351+putrescineCHEBI:1146900+proton+N-acetylputrescine
Reaction pageLeft to rightBalancedEC 2.3.1.57cytosol
Human-GEM MAR08603CC BY 4.0Reference data
an alkane-alpha,omega-diamine+acetyl-CoAan N-acetylalkane-alpha,omega-diamine+coenzyme A(4-)+hydron
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:11116CC BY 4.0Reference data
spermidine+acetyl-CoAN(1)-acetylspermidine+coenzyme A(4-)+hydron
Catalysed by SAT1
Reaction pageLeft to rightBalanced
Rhea RHEA:28150CC BY 4.0Reference data
spermine+acetyl-CoAN(1)-acetylspermine+coenzyme A(4-)+hydron
Catalysed by SAT1
Reaction pageLeft to rightBalanced
Rhea RHEA:33099CC BY 4.0Reference data