3-methylbut-2-enoyl-CoA

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

558 compounds within 3 steps: 4 in 1, 109 in 2, 445 in 3

One step

CHEBI:1146900Reach from here →
1. glycine-N-acyltransferase (3-methylcrotonoylglycine)
Catalysed by GLYATmitochondrial matrix
isovaleryl-CoAReach from here →
1. 3-methylbutanoyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase
Catalysed by IVD, ACADSBmitochondrial matrix
3-methyl-(2E)-glutaconyl-CoAReach from here →
1. 3-Methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)
Catalysed by MCCC1, MCCC2mitochondrial matrixOne of 2 routes
3-hydroxyisovaleryl-CoAReach from here →
1. Fatty Acid Beta Oxidation (C5->C5Oh), Mitochondrial
Catalysed by AUHmitochondrial matrixOne of 2 routes

Two steps

(S)-carnitineReach from here →
1. glycine-N-acyltransferase (3-methylcrotonoylglycine)
2. Carnitine O-Palmitoyltransferase
Catalysed by GLYAT, CPT1A, CPT1C, CPT1Bmitochondrial matrix, cytosolOne of 244 routes
(7Z)-octadecenoyl-CoAReach from here →
1. glycine-N-acyltransferase (3-methylcrotonoylglycine)
2. carnitine O-palmitoyltransferase ((7Z)-octadecenoyl-CoA)
Catalysed by GLYAT, CPT1A, CPT1C, CPT1B

mitochondrial matrix, cytosol

One of 3 routes

CHEBI:15345Reach from here →

Catalysed by GLYAT, AACSmitochondrial matrix, cytosolOne of 2 routes

cholineReach from here →

Catalysed by GLYAT, CHATmitochondrial matrix, nucleus

CHEBI:15380Reach from here →

Catalysed by GLYAT, ALAS1, CPNE7mitochondrial matrixOne of 8 routes

CHEBI:15467Reach from here →

Catalysed by MCCC1, MCCC2, AUHmitochondrial matrix

CHEBI:15477Reach from here →

Catalysed by GLYAT, GLYATL2, GLYATL1mitochondrial matrixOne of 2 routes

2-methylcrotonoyl-CoAReach from here →

Catalysed by GLYAT, CPT1A, CPT1Bmitochondrial matrix, cytosolOne of 2 routes

isobutyryl-CoAReach from here →

Catalysed by GLYAT, HADHA, ACAA2, HADHBmitochondrial matrixOne of 3 routes

arachidonoyl-CoAReach from here →

Catalysed by GLYAT, SLC27A2, ACSL4, ACSL3 and 5 moremitochondrial matrix, cytosolOne of 11 routes

CHEBI:15519Reach from here →

Catalysed by GLYAT, ACAA1, SCP2, MYO5Bmitochondrial matrix, peroxisomeOne of 2 routes

palmitoyl-CoAReach from here →

Catalysed by GLYAT, SLC27A2, ACSL4, ACSL3 and 5 moremitochondrial matrix, cytosolOne of 11 routes

oleoyl-CoAReach from here →

Catalysed by GLYAT, CPT1A, CPT1C, CPT1Bmitochondrial matrix, cytosolOne of 11 routes

phenylacetyl-CoAReach from here →

Catalysed by GLYATmitochondrial matrix, cytosolOne of 3 routes

propionyl-CoAReach from here →

Catalysed by GLYAT, ACSS3, ACSS2, ACSS1mitochondrial matrix, cytosolOne of 43 routes

CHEBI:15650Reach from here →

Catalysed by GLYAT, ZDHHC11B, NAA10, ESCO2 and 29 moremitochondrial matrix, cytosolOne of 2 routes

CHEBI:15727Reach from here →

Catalysed by GLYAT, NAA10mitochondrial matrix, cytosol

CHEBI:15746Reach from here →

Catalysed by GLYAT, SAT1, SAT2mitochondrial matrix, cytosolOne of 2 routes

11-cis-retinolReach from here →

Catalysed by GLYAT, DGAT1, LRAT, AWAT1 and 2 moremitochondrial matrix, cytosol

oxaloacetateReach from here →

Catalysed by GLYAT, ACLYmitochondrial matrix, cytosol

anilineReach from here →

Catalysed by GLYAT, NAT2, NAT1mitochondrial matrix, cytosol

CHEBI:17312Reach from here →

Catalysed by GLYATmitochondrial matrix, cytosolOne of 2 routes

L-cysteineReach from here →

Catalysed by GLYAT, NAGSmitochondrial matrix

(7Z,10Z,13Z)-hexadecatrienoyl-CoAReach from here →

Catalysed by GLYAT, HADHA, ACADVL, HADHBmitochondrial matrix

CHEBI:17927Reach from here →

Catalysed by GLYATmitochondrial matrix, cytosol

(5Z)-dodecenoyl-CoAReach from here →

Catalysed by GLYAT, HADHA, ACAA2, HADHBmitochondrial matrixOne of 2 routes

(11Z)-docosenoyl-CoA(4-)Reach from here →

Catalysed by GLYAT, SLC27A2, ACSL4, ACSL3 and 5 moremitochondrial matrix, cytosolOne of 5 routes

(7Z)-tetradecenoyl-CoAReach from here →

Catalysed by GLYAT, SLC27A2, ACSL4, ACSL3 and 5 moremitochondrial matrix, cytosolOne of 8 routes

(4Z,7Z,10Z,13Z)-hexadecatetraenoyl-CoAReach from here →

Catalysed by GLYAT, HADHA, ACADVL, HADHBmitochondrial matrixOne of 3 routes

(7Z,10Z)-hexadecadienoyl-CoAReach from here →

Catalysed by GLYAT, HADHA, ACADVL, HADHBmitochondrial matrix

(4Z,7Z)-decadienoyl-CoAReach from here →

Catalysed by GLYAT, ECHS1, ACAA2, HADHmitochondrial matrixOne of 2 routes

(5Z)-octenoyl-CoAReach from here →

Catalysed by GLYAT, ECHS1, ACAA2, HADHmitochondrial matrixOne of 2 routes

CHEBI:27540Reach from here →

Catalysed by GLYAT, ACSM4, ACSM1, ACSM2A and 3 moremitochondrial matrix, cytosolOne of 6 routes

elaidic acidReach from here →

Catalysed by GLYAT, SLC27A2, ACSL4, ACSL3 and 5 moremitochondrial matrix, cytosolOne of 5 routes

CHEBI:28701Reach from here →

Catalysed by GLYAT, ACAA1, SCP2, MYO5Bmitochondrial matrix, peroxisomeOne of 7 routes

3-hydroxyisovaleric acidReach from here →

Catalysed by AUHmitochondrial matrix

(3S)-3-hydroxy-3-methylglutaryl-CoAReach from here →

Catalysed by MCCC1, MCCC2, AUHmitochondrial matrix

taurineReach from here →

Catalysed by GLYAT, BAATmitochondrial matrix, cytosolOne of 2 routes

glycineReach from here →

Catalysed by GLYAT, GLYATL2, GLYATL1mitochondrial matrixOne of 10 routes

(R)-methylmalonyl-CoAReach from here →

Catalysed by GLYAT, ALDH6A1mitochondrial matrixOne of 2 routes

(S)-methylmalonyl-CoAReach from here →

Catalysed by GLYATmitochondrial matrix

3'-dephospho-CoAReach from here →

Catalysed by GLYAT, ACP2mitochondrial matrix, lysosomeOne of 2 routes

(2E)-dodecenoyl-CoAReach from here →

Catalysed by GLYATmitochondrial matrixOne of 3 routes

4,8,12-trimethyltridecanoyl-CoAReach from here →

Catalysed by GLYAT, ACAA1, MYO5Bmitochondrial matrix, peroxisomeOne of 2 routes

(6Z,9Z,12Z)-octadecatrienoyl-CoAReach from here →

Catalysed by GLYAT, SLC27A2, ACSL4, ACSL3 and 5 moremitochondrial matrix, cytosolOne of 7 routes

butanoyl-CoAReach from here →

Catalysed by GLYAT, ACSM4, ACSM1, ACSM2A and 3 moremitochondrial matrix, cytosolOne of 9 routes