a 1,2-diacyl-sn-glycerol

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

837 compounds within 3 steps: 18 in 1, 200 in 2, 619 in 3

One step

CHEBI:1146900Reach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 1 morecytosol
phosphatidylethanolamineReach from here →
1. CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase
Catalysed by SELENOI, CEPT1cytosol
1,2-diacyl-sn-glycero-3-phosphocholine(1+)Reach from here →
1. diacylglycerol cholinephosphotransferase (1,2-diacylglycerol-LD-PC pool)
Catalysed by CHPT1, CEPT1cytosol
phosphatidic acidReach from here →
1. Diacylglycerol Phosphate Kinase (Homo Sapiens)
Catalysed by DGKI, DGKZnucleusOne of 2 routes
a 2-acylglycerolReach from here →
1. a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty acid + H(+)
Catalysed by DAGLB, ABHD11, DAGLA
a monoacylglycerolReach from here →
1. 1,2-diacyl-sn-glycerol acylhydrolase
Catalysed by LIPF, LIPC, PNLIP, CEL and 11 moreextracellular spaceOne of 8 routes
a triacylglycerolReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 1 morecytosol
a fatty acidReach from here →
1. a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty acid + H(+)
Catalysed by DAGLB, ABHD11, DAGLA
an N-acylsphinganineReach from here →
1. an N-acylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = an N-acylsphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
Catalysed by SGMS1, SGMS2
an N-acyl-(4R)-4-hydroxysphinganineReach from here →
1. an N-acyl-(4R)-4-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = an N-acyl-(4R)-4-hydroxysphinganine-phosphocholine + a 1,2-diacyl-sn-glycerol
Catalysed by SGMS1, SGMS2
fatty acidReach from here →
1. 1,2-diacyl-sn-glycerol acylhydrolase
Catalysed by LPLextracellular spaceOne of 7 routes
an N-acylsphing-4-enineReach from here →
1. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
Catalysed by SGMS1, SGMS2
a 1,2-diacyl-sn-glycero-3-phosphocholineReach from here →
1. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
Catalysed by SGMS1, SGMS2One of 6 routes
a 1,2-diacyl-sn-glycero-3-phosphateReach from here →
1. a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H(+)
Catalysed by DGKI, DGKA, DGKG, DGKE and 7 more
a 1,2-diacyl-sn-glycero-3-phosphoethanolamineReach from here →
1. CDP-ethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)
Catalysed by SELENOI, CEPT1
a triacyl-sn-glycerolReach from here →
1. an acyl-CoA + a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + CoA
Catalysed by DGAT1, MOGAT2, AWAT2, MOGAT3 and 2 more
N-hexadecanoyl-(4R)-hydroxysphinganineReach from here →
1. N-hexadecanoyl-(4R)-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-(4R)-hydroxysphinganine-phosphocholine + a 1,2-diacyl-sn-glycerol
Catalysed by SGMS1, SGMS2
N-hexadecanoylsphinganineReach from here →
1. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
Catalysed by SGMS1, SGMS2

Two steps

(S)-carnitineReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. Carnitine O-Palmitoyltransferase
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 4 morecytosolOne of 244 routes
CHEBI:12947Reach from here →
1. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
2. UDP-alpha-D-galactose:N-acylsphingosine D-galactosyltransferase
Catalysed by SGMS1, SGMS2, UGT8cytosolOne of 5 routes