Compound
CHEBI:16174
A purine 2'-deoxyribonucleoside 5'-diphosphate having adenine as the nucleobase.
Definition from ChEBI (CHEBI:16174), read 2026-09-23. CC BY 4.0.
What it touches on the way
Mechanistic reach
25 entities
25 entities reached.
0 reported hops25 assembled from the scaffold
- NME1ProteinUNIPROT:P15531substrate ofInferred only140 paths28 endpoints
- NME2ProteinUNIPROT:P22392substrate ofInferred only115 paths23 endpoints
- TXNProteinUNIPROT:P10599substrate ofInferred only112 paths56 endpoints
- PKMProteinUNIPROT:P14618substrate ofInferred only66 paths65 endpoints
- RRM2ProteinUNIPROT:P31350substrate ofInferred only54 paths27 endpoints
- NME7ProteinUNIPROT:Q9Y5B8substrate ofInferred only36 paths12 endpoints
- RRM2BProteinUNIPROT:Q7LG56substrate ofInferred only34 paths17 endpoints
- TXN2ProteinUNIPROT:Q99757substrate ofInferred only34 paths17 endpoints
- NME3ProteinUNIPROT:Q13232substrate ofInferred only32 paths8 endpoints
- RRM1ProteinUNIPROT:P23921substrate ofInferred only30 paths15 endpoints
- NME4ProteinUNIPROT:O00746substrate ofInferred only24 paths6 endpoints
- NME6ProteinUNIPROT:O75414substrate ofInferred only24 paths6 endpoints
Show the remaining 13
- DTYMKProteinUNIPROT:P23919substrate ofInferred only18 paths9 endpoints
- AK5ProteinUNIPROT:Q9Y6K8substrate ofInferred only16 paths8 endpoints
- AK2ProteinUNIPROT:P54819substrate ofInferred only12 paths12 endpoints
- PKLRProteinUNIPROT:P30613substrate ofInferred only11 paths11 endpoints
- AK1ProteinUNIPROT:P00568substrate ofInferred only11 paths11 endpoints
- AK4ProteinUNIPROT:P27144substrate ofInferred only8 paths8 endpoints
- ACAD9ProteinUNIPROT:Q9H845substrate ofInferred only7 paths7 endpoints
- AK7ProteinUNIPROT:Q96M32substrate ofInferred only4 paths4 endpoints
- AK8ProteinUNIPROT:Q96MA6substrate ofInferred only4 paths4 endpoints
- AK9ProteinUNIPROT:Q5TCS8substrate ofInferred only3 paths3 endpoints
- AK6ProteinUNIPROT:Q9Y3D8substrate ofInferred only3 paths3 endpoints
- AK3ProteinUNIPROT:Q9UIJ7substrate ofInferred only2 paths2 endpoints
- CMPK1ProteinUNIPROT:P30085substrate ofInferred only1 path1 endpoint
What the reference databases state
Statements
69 statements
69 statements · 1 reference database · Subject: CHEBI:16174 · Sources: Human-GEM
- CHEBI:16174 is converted to CHEBI:16284CompoundHuman-GEM MAR07869Inferred only
- CHEBI:16174 is converted to CHEBI:16284CompoundHuman-GEM MAR07870Inferred only
- CHEBI:16174 is converted to CHEBI:16284CompoundHuman-GEM MAR08469Inferred only
- CHEBI:16174 is converted to CHEBI:16284CompoundHuman-GEM MAR04044Inferred only
- CHEBI:16284 is converted to CHEBI:16174CompoundHuman-GEM MAR08470Inferred only
- CHEBI:16284 is converted to CHEBI:16174CompoundHuman-GEM MAR04044Inferred only
- CHEBI:16284 is converted to CHEBI:16174CompoundHuman-GEM MAR04420Inferred only
- CHEBI:16284 is converted to CHEBI:16174CompoundHuman-GEM MAR07869Inferred only
- CHEBI:16284 is converted to CHEBI:16174CompoundHuman-GEM MAR07870Inferred only
- CHEBI:16284 is converted to CHEBI:16174CompoundHuman-GEM MAR07892Inferred only
- CHEBI:16284 is converted to CHEBI:16174CompoundHuman-GEM MAR08469Inferred only
- CHEBI:16174 is converted to CHEBI:16284CompoundHuman-GEM MAR08470Inferred only
Show the remaining 57
- CHEBI:16174 is converted to CHEBI:16284CompoundHuman-GEM MAR07892Inferred only
- CHEBI:16174 is a substrate of ACAD9ProteinHuman-GEM MAR04480Inferred only
- CHEBI:16174 is a substrate of AK1ProteinHuman-GEM MAR04480Inferred only
- CHEBI:16174 is a substrate of AK2ProteinHuman-GEM MAR04480Inferred only
- CHEBI:16174 is a substrate of AK3ProteinHuman-GEM MAR04480Inferred only
- CHEBI:16174 is a substrate of AK4ProteinHuman-GEM MAR04480Inferred only
- CHEBI:16174 is a substrate of AK5ProteinHuman-GEM MAR04480Inferred only
- CHEBI:16174 is a substrate of AK5ProteinHuman-GEM MAR07802Inferred only
- CHEBI:16174 is a substrate of AK6ProteinHuman-GEM MAR04480Inferred only
- CHEBI:16174 is a substrate of AK7ProteinHuman-GEM MAR04480Inferred only
- CHEBI:16174 is a substrate of AK8ProteinHuman-GEM MAR04480Inferred only
- CHEBI:16174 is a substrate of AK9ProteinHuman-GEM MAR04480Inferred only
- CHEBI:16174 is a substrate of CMPK1ProteinHuman-GEM MAR07869Inferred only
- CHEBI:16174 is a substrate of CMPK1ProteinHuman-GEM MAR08470Inferred only
- CHEBI:16174 is a substrate of CMPK1ProteinHuman-GEM MAR08454Inferred only
- CHEBI:16174 is a substrate of CMPK1ProteinHuman-GEM MAR08455Inferred only
- CHEBI:16174 is a substrate of CMPK1ProteinHuman-GEM MAR08469Inferred only
- CHEBI:16174 is a substrate of CMPK1ProteinHuman-GEM MAR07870Inferred only
- CHEBI:16174 is a substrate of DTYMKProteinHuman-GEM MAR06612Inferred only
- CHEBI:16174 is a substrate of DTYMKProteinHuman-GEM MAR06613Inferred only
- CHEBI:16174 is a substrate of NME1ProteinHuman-GEM MAR04044Inferred only
- CHEBI:16174 is a substrate of NME1ProteinHuman-GEM MAR07892Inferred only
- CHEBI:16174 is a substrate of NME1ProteinHuman-GEM MAR06614Inferred only
- CHEBI:16174 is a substrate of NME1ProteinHuman-GEM MAR06616Inferred only
- CHEBI:16174 is a substrate of NME1ProteinHuman-GEM MAR06615Inferred only
- CHEBI:16174 is a substrate of NME2ProteinHuman-GEM MAR06614Inferred only
- CHEBI:16174 is a substrate of NME2ProteinHuman-GEM MAR06615Inferred only
- CHEBI:16174 is a substrate of NME2ProteinHuman-GEM MAR07892Inferred only
- CHEBI:16174 is a substrate of NME2ProteinHuman-GEM MAR04044Inferred only
- CHEBI:16174 is a substrate of NME2ProteinHuman-GEM MAR06616Inferred only
- CHEBI:16174 is a substrate of NME3ProteinHuman-GEM MAR06616Inferred only
- CHEBI:16174 is a substrate of NME3ProteinHuman-GEM MAR04044Inferred only
- CHEBI:16174 is a substrate of NME3ProteinHuman-GEM MAR06614Inferred only
- CHEBI:16174 is a substrate of NME3ProteinHuman-GEM MAR06615Inferred only
- CHEBI:16174 is a substrate of NME4ProteinHuman-GEM MAR06615Inferred only
- CHEBI:16174 is a substrate of NME4ProteinHuman-GEM MAR06614Inferred only
- CHEBI:16174 is a substrate of NME4ProteinHuman-GEM MAR06616Inferred only
- CHEBI:16174 is a substrate of NME4ProteinHuman-GEM MAR04044Inferred only
- CHEBI:16174 is a substrate of NME6ProteinHuman-GEM MAR04044Inferred only
- CHEBI:16174 is a substrate of NME6ProteinHuman-GEM MAR06614Inferred only
- CHEBI:16174 is a substrate of NME6ProteinHuman-GEM MAR06615Inferred only
- CHEBI:16174 is a substrate of NME6ProteinHuman-GEM MAR06616Inferred only
- CHEBI:16174 is a substrate of NME7ProteinHuman-GEM MAR06614Inferred only
- CHEBI:16174 is a substrate of NME7ProteinHuman-GEM MAR06615Inferred only
- CHEBI:16174 is a substrate of NME7ProteinHuman-GEM MAR06616Inferred only
- CHEBI:16174 is a substrate of PKLRProteinHuman-GEM MAR04421Inferred only
- CHEBI:16174 is a substrate of PKMProteinHuman-GEM MAR04421Inferred only
- CHEBI:16174 is a substrate of RRM1ProteinHuman-GEM MAR02352Inferred only
- CHEBI:16174 is a substrate of RRM1ProteinHuman-GEM MAR05415Inferred only
- CHEBI:16174 is a substrate of RRM2ProteinHuman-GEM MAR02352Inferred only
- CHEBI:16174 is a substrate of RRM2ProteinHuman-GEM MAR05415Inferred only
- CHEBI:16174 is a substrate of RRM2BProteinHuman-GEM MAR05415Inferred only
- CHEBI:16174 is a substrate of RRM2BProteinHuman-GEM MAR02352Inferred only
- CHEBI:16174 is a substrate of TXNProteinHuman-GEM MAR02352Inferred only
- CHEBI:16174 is a substrate of TXNProteinHuman-GEM MAR05415Inferred only
- CHEBI:16174 is a substrate of TXN2ProteinHuman-GEM MAR02352Inferred only
- CHEBI:16174 is a substrate of TXN2ProteinHuman-GEM MAR05415Inferred only
Reactions
25 reactions
CHEBI:16174+water+thioredoxin disulfideADP+thioredoxin dithiol
Catalysed by RRM1 & RRM2 & RRM2B & TXN2 or TXN & RRM1 & RRM2 & RRM2B
Reaction pageLeft to rightBalancedEC 1.17.4.1mitochondrial matrix
Human-GEM MAR02352CC BY 4.0Reference data
ADP+CHEBI:16284ATP+CHEBI:16174
Catalysed by NME3 or NME4 or NME6 or NME1 or NME2
Reaction pageReversibleBalancedEC 2.7.4.6cytosol
Human-GEM MAR04044CC BY 4.0Reference data
ADP+CHEBI:16284ATP+CHEBI:16174
Catalysed by NME3 or NME4 or NME7 or NME6 or NME1 or NME2
Reaction pageLeft to rightBalancedEC 2.7.4.6mitochondrial matrix
Human-GEM MAR04420CC BY 4.0Reference data
CHEBI:16174+proton+phosphoenolpyruvic acidCHEBI:16284+pyruvate
Reaction pageLeft to rightBalancedEC 2.7.1.40cytosol
Human-GEM MAR04421CC BY 4.0Reference data
ADP+CHEBI:16174ATP+MAM01639c
Catalysed by AK2 or AK6 or AK1 or AK7 or AK3 or AK5 or AK9 or AK4 or AK8 or ACAD9
Reaction pageReversibleBalancedEC 2.7.4.11, 2.7.4.3cytosol
Human-GEM MAR04480CC BY 4.0Reference data
CHEBI:16284+D-glucoseCHEBI:16174+D-glucopyranose 6-phosphate+proton
Catalysed by HKDC1 or HK1 or HK2 or HK3
Reaction pageLeft to rightBalancedEC 2.7.1.1cytosol
Human-GEM MAR04487CC BY 4.0Reference data
CHEBI:16284+beta-D-fructoseCHEBI:16174+keto-D-fructose 6-phosphate+proton
Catalysed by HKDC1 or HK1 or HK2 or HK3
Reaction pageLeft to rightBalancedEC 2.7.1.1cytosol
Human-GEM MAR04489CC BY 4.0Reference data
CHEBI:16284+D-mannoseCHEBI:16174+proton+MAM02455c
Catalysed by HKDC1 or HK1 or HK2 or HK3
Reaction pageLeft to rightBalancedEC 2.7.1.1cytosol
Human-GEM MAR04493CC BY 4.0Reference data
CHEBI:16284+glucosamineCHEBI:16174+alpha-D-glucosamine 6-phosphate+proton
Catalysed by HKDC1 or HK1 or HK2
Reaction pageLeft to rightBalancedEC 2.7.1.1cytosol
Human-GEM MAR04496CC BY 4.0Reference data
ADP+thioredoxin dithiolCHEBI:16174+water+thioredoxin disulfide
Catalysed by RRM1 & RRM2 & RRM2B & TXN2 or TXN & RRM1 & RRM2 & RRM2B
Reaction pageLeft to rightBalancedEC 1.17.4.1cytosol
Human-GEM MAR04612CC BY 4.0Reference data
CHEBI:16174+water+thioredoxin disulfideADP+thioredoxin dithiol
Catalysed by RRM1 & RRM2 & RRM2B & TXN2 or TXN & RRM1 & RRM2 & RRM2B
Reaction pageLeft to rightBalancedEC 1.17.4.1mitochondrial matrix
Human-GEM MAR05415CC BY 4.0Reference data
CHEBI:16174+dTDPCHEBI:16284+dTMP
Catalysed by DTYMK
Reaction pageReversibleBalancedEC 2.7.4.9mitochondrial matrix
Human-GEM MAR06612CC BY 4.0Reference data
Other names
5 names
Resolves to: CHEBI:16174
- Also called
- 2'-Deoxyadenosine 5'-diphosphate2'-DEOXYADENOSINE-5'-DIPHOSPHATEdADPdeoxyadenosine diphosphate
- Systematic name
- 2'-deoxyadenosine 5'-(trihydrogen diphosphate)