Compound
CHEBI:28862
A purine 2'-deoxyribonucleoside 5'-diphosphate having guanine as the nucleobase.
Definition from ChEBI (CHEBI:28862), read 2026-09-23. CC BY 4.0.
What it touches on the way
Mechanistic reach
16 entities
16 entities reached.
0 reported hops16 assembled from the scaffold
- TXNProteinUNIPROT:P10599substrate ofInferred only112 paths56 endpoints
- PKMProteinUNIPROT:P14618substrate ofInferred only66 paths65 endpoints
- NME1ProteinUNIPROT:P15531substrate ofInferred only64 paths32 endpoints
- RRM2ProteinUNIPROT:P31350substrate ofInferred only56 paths28 endpoints
- NME2ProteinUNIPROT:P22392substrate ofInferred only52 paths26 endpoints
- SLC25A36ProteinUNIPROT:Q96CQ1transported byInferred only39 paths39 endpoints
- RRM1ProteinUNIPROT:P23921substrate ofInferred only36 paths18 endpoints
- RRM2BProteinUNIPROT:Q7LG56substrate ofInferred only34 paths17 endpoints
- TXN2ProteinUNIPROT:Q99757substrate ofInferred only34 paths17 endpoints
- CMPK1ProteinUNIPROT:P30085substrate ofInferred only20 paths4 endpoints
- NME7ProteinUNIPROT:Q9Y5B8substrate ofInferred only12 paths12 endpoints
- PKLRProteinUNIPROT:P30613substrate ofInferred only11 paths11 endpoints
What the reference databases state
Statements
43 statements
43 statements · 1 reference database · Subject: CHEBI:28862 · Sources: Human-GEM
- CHEBI:16497 is converted to CHEBI:28862CompoundHuman-GEM MAR04570Inferred only
- CHEBI:16497 is converted to CHEBI:28862CompoundHuman-GEM MAR04572Inferred only
- CHEBI:16497 is converted to CHEBI:28862CompoundHuman-GEM MAR08449Inferred only
- CHEBI:28862 is converted to CHEBI:16497CompoundHuman-GEM MAR04570Inferred only
- CHEBI:28862 is converted to CHEBI:16497CompoundHuman-GEM MAR07873Inferred only
- CHEBI:28862 is converted to CHEBI:16497CompoundHuman-GEM MAR07874Inferred only
- CHEBI:28862 is converted to CHEBI:16497CompoundHuman-GEM MAR07888Inferred only
- CHEBI:28862 is converted to CHEBI:16497CompoundHuman-GEM MAR08448Inferred only
- CHEBI:28862 is converted to CHEBI:16497CompoundHuman-GEM MAR08449Inferred only
- CHEBI:16497 is converted to CHEBI:28862CompoundHuman-GEM MAR07873Inferred only
- CHEBI:16497 is converted to CHEBI:28862CompoundHuman-GEM MAR07888Inferred only
- CHEBI:16497 is converted to CHEBI:28862CompoundHuman-GEM MAR08448Inferred only
Show the remaining 31
- CHEBI:16497 is converted to CHEBI:28862CompoundHuman-GEM MAR07874Inferred only
- dGMP is converted to CHEBI:28862CompoundHuman-GEM MAR05353Inferred only
- CHEBI:28862 is converted to dGMPCompoundHuman-GEM MAR05353Inferred only
- CHEBI:28862 is a substrate of CMPK1ProteinHuman-GEM MAR08449Inferred only
- CHEBI:28862 is a substrate of CMPK1ProteinHuman-GEM MAR08448Inferred only
- CHEBI:28862 is a substrate of CMPK1ProteinHuman-GEM MAR07873Inferred only
- CHEBI:28862 is a substrate of CMPK1ProteinHuman-GEM MAR08451Inferred only
- CHEBI:28862 is a substrate of CMPK1ProteinHuman-GEM MAR07874Inferred only
- CHEBI:28862 is a substrate of GUK1ProteinHuman-GEM MAR05353Inferred only
- CHEBI:28862 is a substrate of NME1ProteinHuman-GEM MAR07888Inferred only
- CHEBI:28862 is a substrate of NME1ProteinHuman-GEM MAR04570Inferred only
- CHEBI:28862 is a substrate of NME2ProteinHuman-GEM MAR04570Inferred only
- CHEBI:28862 is a substrate of NME2ProteinHuman-GEM MAR07888Inferred only
- CHEBI:28862 is a substrate of NME3ProteinHuman-GEM MAR04570Inferred only
- CHEBI:28862 is a substrate of NME4ProteinHuman-GEM MAR04570Inferred only
- CHEBI:28862 is a substrate of NME6ProteinHuman-GEM MAR04570Inferred only
- CHEBI:28862 is a substrate of NME7ProteinHuman-GEM MAR04570Inferred only
- CHEBI:28862 is a substrate of PKLRProteinHuman-GEM MAR04573Inferred only
- CHEBI:28862 is a substrate of PKMProteinHuman-GEM MAR04573Inferred only
- CHEBI:28862 is a substrate of RRM1ProteinHuman-GEM MAR02357Inferred only
- CHEBI:28862 is a substrate of RRM1ProteinHuman-GEM MAR05416Inferred only
- CHEBI:28862 is a substrate of RRM2ProteinHuman-GEM MAR02357Inferred only
- CHEBI:28862 is a substrate of RRM2ProteinHuman-GEM MAR05416Inferred only
- CHEBI:28862 is a substrate of RRM2BProteinHuman-GEM MAR05416Inferred only
- CHEBI:28862 is a substrate of RRM2BProteinHuman-GEM MAR02357Inferred only
- CHEBI:28862 is a substrate of TXNProteinHuman-GEM MAR05416Inferred only
- CHEBI:28862 is a substrate of TXNProteinHuman-GEM MAR02357Inferred only
- CHEBI:28862 is a substrate of TXN2ProteinHuman-GEM MAR02357Inferred only
- CHEBI:28862 is a substrate of TXN2ProteinHuman-GEM MAR05416Inferred only
- CHEBI:28862 is transported by SLC25A33ProteinHuman-GEM MAR20158Inferred only
- CHEBI:28862 is transported by SLC25A36ProteinHuman-GEM MAR20141Inferred only
Reactions
20 reactions
CHEBI:28862+water+thioredoxin disulfideGDP+thioredoxin dithiol
Catalysed by RRM1 & RRM2 & RRM2B & TXN2 or TXN & RRM1 & RRM2 & RRM2B
Reaction pageLeft to rightBalancedEC 1.17.4.1mitochondrial matrix
Human-GEM MAR02357CC BY 4.0Reference data
ADP+CHEBI:16497ATP+CHEBI:28862
Catalysed by NME3 or NME4 or NME7 or NME6 or NME1 or NME2
Reaction pageReversibleBalancedEC 2.7.4.6cytosol
Human-GEM MAR04570CC BY 4.0Reference data
ADP+CHEBI:16497ATP+CHEBI:28862
Catalysed by NME3 or NME4 or NME7 or NME6 or NME1 or NME2
Reaction pageLeft to rightBalancedEC 2.7.4.6mitochondrial matrix
Human-GEM MAR04572CC BY 4.0Reference data
CHEBI:28862+proton+phosphoenolpyruvic acidCHEBI:16497+pyruvate
Reaction pageLeft to rightBalancedEC 2.7.1.40cytosol
Human-GEM MAR04573CC BY 4.0Reference data
GDP+thioredoxin dithiolCHEBI:28862+water+thioredoxin disulfide
Catalysed by RRM1 & RRM2 & RRM2B & TXN2 or TXN & RRM1 & RRM2 & RRM2B
Reaction pageLeft to rightBalancedEC 1.17.4.1cytosol
Human-GEM MAR04615CC BY 4.0Reference data
Catalysed by GUK1
Reaction pageReversibleBalancedEC 2.7.4.8cytosol
Human-GEM MAR05353CC BY 4.0Reference data
CHEBI:28862+water+thioredoxin disulfideGDP+thioredoxin dithiol
Catalysed by RRM1 & RRM2 & RRM2B & TXN2 or TXN & RRM1 & RRM2 & RRM2B
Reaction pageLeft to rightBalancedEC 1.17.4.1mitochondrial matrix
Human-GEM MAR05416CC BY 4.0Reference data
2'-deoxyuridine+CHEBI:16497CHEBI:28862+dUMP+proton
Reaction pageLeft to rightBalancedEC 2.7.1.21cytosol
Human-GEM MAR06623CC BY 4.0Reference data
2'-deoxyuridine+CHEBI:16497CHEBI:28862+dUMP+proton
Catalysed by TK2
Reaction pageLeft to rightBalancedEC 2.7.1.21mitochondrial matrix
Human-GEM MAR06624CC BY 4.0Reference data
adenosine+CHEBI:16497AMP+CHEBI:28862+proton
Reaction pageLeft to rightBalancedcytosol
Human-GEM MAR07803CC BY 4.0Reference data
CHEBI:28862+UDPCHEBI:16497+UMP
Catalysed by CMPK1
Reaction pageReversibleBalancedEC 2.7.4.14cytosol
Human-GEM MAR07873CC BY 4.0Reference data
CHEBI:28862+UDPCHEBI:16497+UMP
Catalysed by CMPK1
Reaction pageReversibleBalancedEC 2.7.4.14nucleus
Human-GEM MAR07874CC BY 4.0Reference data
Where it reaches
7 systems, 13 regions, 39 tissues, 39 transporter routes — routes, not measurements: transporters known to carry CHEBI:28862 are expressed there, and no source reports it arriving.
Loading the model…
Other names
4 names
Resolves to: CHEBI:28862
- Also called
- 2'-deoxyguanosine 5'-diphosphatedeoxyguanosine diphosphatedGDP
- Systematic name
- 2'-deoxyguanosine 5'-(trihydrogen diphosphate)