Compound
D-glucopyranose 6-phosphate
A glucopyranose ring with a phosphate replacing the hydroxy in the hydroxymethyl group at position 6.
Definition from ChEBI (CHEBI:4170), read 2026-09-23. CC BY 4.0.
What it touches on the way
Mechanistic reach
10 entities
10 entities reached.
0 reported hops10 assembled from the scaffold
- G6PDProteinUNIPROT:P11413substrate ofInferred only68 paths34 endpoints
- PGM1ProteinUNIPROT:P36871substrate ofInferred only34 paths34 endpoints
- G6PC1ProteinUNIPROT:P35575substrate ofInferred only33 paths33 endpoints
- GPIProteinUNIPROT:P06744substrate ofInferred only30 paths30 endpoints
- G6PC3ProteinUNIPROT:Q9BUM1substrate ofInferred only11 paths11 endpoints
- PGM2ProteinUNIPROT:Q96G03substrate ofInferred only9 paths9 endpoints
- G6PC2ProteinUNIPROT:Q9NQR9substrate ofInferred only7 paths7 endpoints
- SLC37A4ProteinUNIPROT:O43826transported byInferred only4 paths2 endpoints
- ISYNA1ProteinUNIPROT:Q9NPH2substrate ofInferred only3 paths3 endpoints
- H6PDProteinUNIPROT:O95479substrate ofInferred only2 paths2 endpoints
What the reference databases state
Chemical structure
- D-glucopyranose 6-phosphate has the functional parent D-glucoseCompoundChEBI CHEBI:4170Inferred only
Statements
23 statements
23 statements · 1 reference database · Subject: D-glucopyranose 6-phosphate · Sources: Human-GEM
- 1D-myo-inositol 1-phosphate is converted to D-glucopyranose 6-phosphateCompoundHuman-GEM MAR04308Inferred only
- D-glucopyranose 6-phosphate is converted to 1D-myo-inositol 3-phosphateCompoundHuman-GEM MAR06572Inferred only
- 6-phospho-D-glucono-1,5-lactone is converted to D-glucopyranose 6-phosphateCompoundHuman-GEM MAR08653Inferred only
- D-glucopyranose 6-phosphate is converted to 6-phospho-D-glucono-1,5-lactoneCompoundHuman-GEM MAR04304Inferred only
- D-glucopyranose 6-phosphate is converted to 6-phospho-D-glucono-1,5-lactoneCompoundHuman-GEM MAR08653Inferred only
- D-glucopyranose 6-phosphate is converted to 6-phospho-D-glucono-1,5-lactoneCompoundHuman-GEM MAR08971Inferred only
- D-glucose is converted to D-glucopyranose 6-phosphateCompoundHuman-GEM MAR04394Inferred only
- D-glucose is converted to D-glucopyranose 6-phosphateCompoundHuman-GEM MAR07747Inferred only
- D-glucopyranose 6-phosphate is converted to D-glucoseCompoundHuman-GEM MAR04521Inferred only
- D-glucopyranose 6-phosphate is converted to keto-D-fructose 6-phosphateCompoundHuman-GEM MAR04381Inferred only
- keto-D-fructose 6-phosphate is converted to D-glucopyranose 6-phosphateCompoundHuman-GEM MAR04381Inferred only
- D-glucopyranose 6-phosphate is a substrate of G6PC1ProteinHuman-GEM MAR04521Inferred only
Show the remaining 11
- D-glucopyranose 6-phosphate is a substrate of G6PC2ProteinHuman-GEM MAR04521Inferred only
- D-glucopyranose 6-phosphate is a substrate of G6PC3ProteinHuman-GEM MAR04521Inferred only
- D-glucopyranose 6-phosphate is a substrate of G6PDProteinHuman-GEM MAR04304Inferred only
- D-glucopyranose 6-phosphate is a substrate of G6PDProteinHuman-GEM MAR08971Inferred only
- D-glucopyranose 6-phosphate is a substrate of GPIProteinHuman-GEM MAR04381Inferred only
- D-glucopyranose 6-phosphate is a substrate of H6PDProteinHuman-GEM MAR08653Inferred only
- D-glucopyranose 6-phosphate is a substrate of ISYNA1ProteinHuman-GEM MAR06572Inferred only
- D-glucopyranose 6-phosphate is a substrate of PGM1ProteinHuman-GEM MAR04396Inferred only
- D-glucopyranose 6-phosphate is a substrate of PGM2ProteinHuman-GEM MAR04396Inferred only
- D-glucopyranose 6-phosphate is transported by SLC37A4ProteinHuman-GEM MAR06386Inferred only
- D-glucopyranose 6-phosphate is transported by SLC37A4ProteinHuman-GEM MAR04856Inferred only
Reactions
19 reactions
D-glucopyranose 6-phosphate+NADP(3-)6-phospho-D-glucono-1,5-lactone+proton+NADPH(4-)
Catalysed by G6PD
Reaction pageLeft to rightBalancedEC 1.1.1.49endoplasmic reticulum
Human-GEM MAR04304CC BY 4.0Reference data
1D-myo-inositol 1-phosphateD-glucopyranose 6-phosphate
Catalysed by ISYNA1
Reaction pageLeft to rightBalancedEC 5.5.1.4cytosol
Human-GEM MAR04308CC BY 4.0Reference data
keto-D-fructose 6-phosphateD-glucopyranose 6-phosphate
Catalysed by GPI
Reaction pageReversibleBalancedEC 5.3.1.9cytosol
Human-GEM MAR04381CC BY 4.0Reference data
ATP+D-glucoseADP+D-glucopyranose 6-phosphate+proton
Catalysed by GCK or HKDC1 or HK1 or HK2 or HK3
Reaction pageLeft to rightBalancedEC 2.7.1.1, 2.7.1.2, 2.7.1.147cytosol
Human-GEM MAR04394CC BY 4.0Reference data
MAM01967cD-glucopyranose 6-phosphate
Reaction pageReversibleBalancedEC 5.4.2.2, 5.4.2.5, 5.4.2.6cytosol
Human-GEM MAR04396CC BY 4.0Reference data
0.505626L-alanine+0.35926L-arginine+0.279425L-asparagine+0.352607L-aspartate+20.704451ATP+0.020401CHEBI:1307929+0.011658a cardiolipin+0.039036CHEBI:17677+0.046571L-cysteine+0.013183CHEBI:16284+0.009442dCTP+0.009898CHEBI:16497+0.013091dTTP+0.275194D-glucopyranose 6-phosphate+0.385872L-glutamate(1-)+0.325996L-glutamine+0.538891glycine+0.036117GTP+20.650823water+0.126406CHEBI:15971+0.286078L-isoleucine+0.545544L-leucine+0.592114CHEBI:18019+0.153018L-methionine+0.1544631,2-diacyl-sn-glycero-3-phosphocholine(1+)+0.055374phosphatidylethanolamine+0.002914MAM02715c+0.259466L-phenylalanine+0.0233151-phosphatidyl-1D-myo-inositol+0.412484CHEBI:17203+0.005829phosphatidyl-L-serine+0.392525L-seryl residue+0.017486a sphingomyelin+0.31269CHEBI:16857+0.013306L-tryptophan+0.159671CHEBI:17895+0.053446UTP+0.352607L-valine20.650823ADP+20.650823proton+20.650823phosphate(3-)+MAM03970c
Reaction pageBlockedBalance undeterminablecytosol, nucleus
Human-GEM MAR04413CC BY 4.0Reference data
D-glucose+CHEBI:16039D-glucopyranose 6-phosphate+proton+CHEBI:17808
Catalysed by HKDC1 or HK1 or HK2 or HK3
Reaction pageLeft to rightBalancedEC 2.7.1.1cytosol
Human-GEM MAR04486CC BY 4.0Reference data
CHEBI:16284+D-glucoseCHEBI:16174+D-glucopyranose 6-phosphate+proton
Catalysed by HKDC1 or HK1 or HK2 or HK3
Reaction pageLeft to rightBalancedEC 2.7.1.1cytosol
Human-GEM MAR04487CC BY 4.0Reference data
D-glucopyranose 6-phosphate+waterD-glucose+phosphate(3-)
Catalysed by G6PC1 or G6PC3 or G6PC2
Reaction pageLeft to rightBalancedEC 3.1.3.9endoplasmic reticulum
Human-GEM MAR04521CC BY 4.0Reference data
D-glucopyranose 6-phosphateD-glucopyranose 6-phosphate
Transported by SLC37A4
Reaction pageReversibleBalancedcytosol, endoplasmic reticulum
Human-GEM MAR04856CC BY 4.0Reference data
D-glucopyranose 6-phosphate+phosphate(3-)D-glucopyranose 6-phosphate+phosphate(3-)
Transported by SLC37A4
Reaction pageLeft to rightBalancedcytosol, endoplasmic reticulum
Human-GEM MAR06386CC BY 4.0Reference data
D-glucopyranose 6-phosphate1D-myo-inositol 3-phosphate
Catalysed by ISYNA1
Reaction pageLeft to rightBalancedEC 5.5.1.4cytosol
Human-GEM MAR06572CC BY 4.0Reference data
Other names
5 names
Resolves to: D-glucopyranose 6-phosphate
- Also called
- 6-O-phosphono-D-glucopyranoseD-Glucose 6-phosphateGlc6PRobison ester
- Systematic name
- D-glucopyranose 6-(dihydrogen phosphate)