N(1),N(12)-diacetylspermine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

159 compounds within 3 steps: 4 in 1, 6 in 2, 149 in 3

One step

CHEBI:17312Reach from here →
1. N1,N12-diacetylspermine to N1-acetylspermine conversion
No catalyst recordedcytosolOne of 2 routes
CHEBI:17927Reach from here →
1. N(1)-acetylpolyamine oxidase (N1,N12-diacetylspermine)
Catalysed by PAOX, SMOXcytosolOne of 2 routes
3-acetamidopropanalReach from here →
1. N(1)-acetylpolyamine oxidase (N1,N12-diacetylspermine)
Catalysed by PAOX, SMOXcytosolOne of 3 routes
N(1)-acetylspermidineReach from here →
1. N(1),N(12)-diacetylspermine + O2 + H2O = 3-acetamidopropanal + N(1)-acetylspermidine + H2O2
Catalysed by PAOX

Two steps

CHEBI:1146900Reach from here →
1. N1,N12-diacetylspermine to N1-acetylspermine conversion
2. N1,N12-diacetylspermine to N1-acetylspermine conversion
No catalyst recordedcytosolOne of 3 routes
CHEBI:15746Reach from here →
1. N1,N12-diacetylspermine to N1-acetylspermine conversion
2. diamine N-acetyltransferase (N1-acetylspermine)
Catalysed by SAT1, SAT2cytosolOne of 2 routes
L-arginineReach from here →

Three steps

N(1)-acetylpolyamine oxidase (N1,N12-diacetylspermine)

Transport by Y+Lat-2 into Extracellular Space

Catalysed by PAOX, SMOX, SLC3A2, SLC7A6cytosol, extracellular space

putrescineReach from here →

Catalysed by PAOX, SMOXcytosolOne of 3 routes

spermidineReach from here →

Catalysed by PAOX, SMOXcytosolOne of 4 routes

N(1)-acetylspermineReach from here →

Catalysed by PAOX, SMOXcytosol

PAOX

, SMOX

, SLC3A2

, SLC7A6

cytosol, extracellular space, inner side of the membrane, outer side of the membrane

One of 2 routes

L-homoarginineReach from here →

Catalysed by PAOX, SMOX, SLC3A2, SLC7A6 and 1 morecytosol, extracellular space, inner side of the membrane, outer side of the membraneOne of 2 routes

(7Z)-octadecenoyl-CoAReach from here →

Catalysed by CPT1A, CPT1C, CPT1BcytosolOne of 3 routes

CHEBI:15345Reach from here →

Catalysed by AACScytosolOne of 2 routes

cholineReach from here →

Catalysed by CHATcytosol, nucleus

CHEBI:15380Reach from here →

Catalysed by ALAS1, CPNE7cytosol, mitochondrial matrixOne of 8 routes

CHEBI:15477Reach from here →

Catalysed by GLYAT, GLYATL2, GLYATL1cytosol, mitochondrial matrixOne of 2 routes

2-methylcrotonoyl-CoAReach from here →

Catalysed by CPT1A, CPT1BcytosolOne of 2 routes

isobutyryl-CoAReach from here →

Catalysed by HADHA, ACAA2, HADHBcytosol, mitochondrial matrixOne of 3 routes

3-methylbut-2-enoyl-CoAReach from here →

Catalysed by GLYATcytosol, mitochondrial matrix

isovaleryl-CoAReach from here →

Catalysed by GLYAT, GLYATL2, GLYATL1cytosol, mitochondrial matrixOne of 3 routes

arachidonoyl-CoAReach from here →

Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 4 morecytosolOne of 11 routes

CHEBI:15519Reach from here →

Catalysed by ACAA1, SCP2, MYO5Bcytosol, peroxisomeOne of 2 routes

palmitoyl-CoAReach from here →

Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 4 morecytosolOne of 11 routes

oleoyl-CoAReach from here →

Catalysed by CPT1A, CPT1C, CPT1BcytosolOne of 11 routes

phenylacetyl-CoAReach from here →

No catalyst recordedcytosolOne of 3 routes

propionyl-CoAReach from here →

Catalysed by ACSS3, ACSS2, ACSS1cytosolOne of 43 routes

L-leucineReach from here →

Catalysed by PAOX, SMOX, SLC3A2, SLC7A6 and 1 morecytosol, extracellular spaceOne of 6 routes

CHEBI:15650Reach from here →

Catalysed by ZDHHC11B, NAA10, ESCO2, ESCO1 and 28 morecytosolOne of 2 routes

CHEBI:15699Reach from here →

Catalysed by PAOX, SMOX, SLC3A2, SLC7A6cytosol, extracellular spaceOne of 2 routes

trimethylenediamineReach from here →

Catalysed by PAOX, SMOX, DHPScytosolOne of 2 routes

CHEBI:15727Reach from here →

Catalysed by NAA10cytosol

CHEBI:15971Reach from here →

Catalysed by PAOX, SMOX, SLC3A2, SLC7A6 and 1 morecytosol, extracellular spaceOne of 6 routes

ureaReach from here →

Catalysed by PAOX, SMOX, SLC3A2, SLC7A6 and 1 morecytosol, extracellular spaceOne of 3 routes

L-cystineReach from here →

Catalysed by PAOX, SMOX, SLC3A2, SLC7A6 and 1 morecytosol, extracellular space, inner side of the membrane, outer side of the membrane

11-cis-retinolReach from here →

Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 1 morecytosol

L-citrullineReach from here →

Catalysed by PAOX, SMOX, SLC3A2, SLC7A6 and 3 morecytosol, extracellular spaceOne of 7 routes

L-valineReach from here →

Catalysed by PAOX, SMOX, SLC3A2, SLC7A6cytosol, extracellular spaceOne of 2 routes

oxaloacetateReach from here →

Catalysed by ACLYcytosol

nitric oxideReach from here →

Catalysed by PAOX, SMOX, SLC3A2, SLC7A6 and 3 morecytosol, extracellular spaceOne of 2 routes

protein polypeptide chainReach from here →

Catalysed by PAOX, SMOX, SLC3A2, SLC7A6cytosol, extracellular space

CHEBI:16857Reach from here →

Catalysed by PAOX, SMOX, SLC3A2, SLC7A6cytosol, extracellular spaceOne of 2 routes

L-isoleucineReach from here →

Catalysed by PAOX, SMOX, SLC3A2, SLC7A6cytosol, extracellular spaceOne of 2 routes

CHEBI:17203Reach from here →

Catalysed by PAOX, SMOX, SLC3A2, SLC7A6cytosol, extracellular spaceOne of 2 routes

anilineReach from here →

Catalysed by NAT2, NAT1cytosol

agmatineReach from here →

Catalysed by PAOX, SMOX, SLC3A2, SLC7A6cytosol, extracellular space, mitochondrial matrix

S-methyl-5'-thioadenosineReach from here →

Catalysed by PAOX, SMOX, SRM, SMScytosolOne of 4 routes

L-cysteineReach from here →

Catalysed by NAGScytosol, mitochondrial matrixOne of 6 routes

(7Z,10Z,13Z)-hexadecatrienoyl-CoAReach from here →

Catalysed by HADHA, ACADVL, HADHBcytosol, mitochondrial matrix